Improvement of Obstructive Sleep Apnea–Hypopnea Syndrome in Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy: Prospective Study

2020 ◽  
Vol 15 (3) ◽  
pp. 131-139
Author(s):  
Mohamed Abdalla Salman ◽  
Basem Othman ◽  
Ahmed Abdallah Salman ◽  
Ahmed Abdallah ◽  
Hesham Elkassar ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleeve Gastrectomy ◽  
Sleep Apnea ◽  
Prospective Study ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome

scholarly journals The Effect of Laparoscopic Sleeve Gastrectomy on Obstructive Sleep Apnea Syndrome

2018 ◽  
Author(s):  
Tuğrul Çakır ◽  
Hülya Eyigör ◽  
Arif Aslaner ◽  
Nurullah Bülbüller ◽  
Mehmet Tahir Oruç ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleeve Gastrectomy ◽  
Sleep Apnea ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Morbidly Obese ◽  
Safe Procedure ◽  
Obese Patients ◽  
Obstructive Sleep ◽  
Severely Obese ◽  
The Mean

Background: The repeated episode of obstructive hypopnea and apnea during sleep is defined as obstructive sleep apnea (OSA) and it is a common condition in obese patients. Studies performing bariatric surgery have demonstrated a significant improvement in OSA by weight reduction. In this prospective study we aimed to explore the efficacy and safety of Laparoscopic Sleeve Gastrectomy (LSG) on OSAS among severely obese patients. Material and Methods: A total of 32 morbidly obese patients who underwent LSG for morbid obesity were included in this study. Body weight, height, body mass index (BMI) and standard overnight polysomnography (PSG) were measured at before and after LSG at the 6th month.  Results: 32 patients (27 female, 5 male) who have postoperative PSG's were included in this study. The mean age was 43.22±9.87 years old. The mean preoperative and postoperative BMIs were 50.36±8.14kg/m² and 37.27±7.93kg/m², respectively. The mean Epworth sleepiness scale determined as 5.84±4.65 preoperatively and 2.19±3.55 postoperatively. The preoperative and postoperative sleep efficiency test of the patients was determined as 83.34±9.68 and 88.94±6.90 respectively. AHI average at the preoperative PSG was 31.47±26.34, while 9.35±10:34 at postoperative 6 months and found as statistically significant. Conclusion: Our data showed that LSG is an efficient and safe procedure on severely obese patients and showed a predictive remission of clinical and sleep parameters of patients with OSA by analyzing PSG data during the first 6 months.

Relationship between Obstructive Sleep Apnea and Liver Abnormalities in Morbidly Obese Patients: A Prospective Study

2007 ◽  
Vol 17 (4) ◽  
pp. 478-485 ◽  
Author(s):  
Pauline Jouët ◽  
Jean-Marc Sabaté ◽  
Dominique Maillard ◽  
Simon Msika ◽  
Charlotte Mechler ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Prospective Study ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Obstructive Sleep ◽  
A Prospective Study

scholarly journals Association of Metabolic Syndrome With Prevalence of Obstructive Sleep Apnea and Remission After Sleeve Gastrectomy

2021 ◽  
Vol 12 ◽  
Author(s):  
Yufei Chen ◽  
Lijia Chen ◽  
Lingxia Ye ◽  
Jiabin Jin ◽  
Yingkai Sun ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Obstructive Sleep Apnea ◽  
Sleeve Gastrectomy ◽  
Sleep Apnea ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Apnea Hypopnea Index ◽  
Obese Patients ◽  
Metabolic States ◽  
Obstructive Sleep ◽  
Metabolically Healthy

Obesity is an important risk factor for metabolic syndrome and obstructive sleep apnea (OSA). Bariatric surgery has been shown to effectively reduce weight and obesity-related comorbidities. However, the prevalence and severity of OSA in obese patients with different baseline metabolic states and the improvements of OSA after bariatric surgery remain unknown. The main aims of this study were to ascertain the prevalence of OSA in young Chinese obese patients with different metabolic states and to evaluate their respective OSA remission after laparoscopic sleeve gastrectomy. We first performed a cross-sectional study involving 123 metabolically healthy obese patients and 200 metabolically unhealthy obese patients (who had the same age and BMI ranges) to estimate the prevalence of OSA at baseline. Then we performed a retrospective study, which was registered at ClinicalTrials.gov (ref. NCT02653430) of 67 patients who underwent laparoscopic sleeve gastrectomy to evaluate the remission of OSA. Metabolically healthy and unhealthy obese patients had similar apnea-hypopnea index levels (16.6 ± 22.0 vs. 16.7 ± 18.7 events/h, P = 0.512) and prevalence of OSA (66.7% vs. 69.0%, P = 0.662). Male sex, age, waist circumference and lower liver-to-spleen ratio were independent risk factors for OSA. After laparoscopic sleeve gastrectomy, no difference was found in the decrease in body mass index (BMI) change (10.8 ± 4.8 vs. 10.8 ± 3.0 kg/m2, P = 0.996) or the decrease in the apnea-hypopnea index (18.9 ± 24.6 vs. 17.0 ± 24.0 events/h, P = 0.800). The remission of moderate-to-severe OSA was observed in the MHO (36.3%; 54.5–18.2%, P = 0.125) and MUO (32.2%; 66.1–33.9%, P = 0.001) patients. These results suggest that, in patients with obesity, metabolic syndrome does not add extra risk for the prevalence or severity of OSA. Both metabolically healthy and unhealthy obese patients could benefit equally from laparoscopic sleeve gastrectomy in terms of weight loss and obstructive sleep apnea remission.

Improvement in Obstructive Sleep Apnea (OSA) in Super Morbidly Obese Patients After Bariatric Surgery

2020 ◽  
Vol 103 (8) ◽  
pp. 725-728
Keyword(s):  
Bariatric Surgery ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Lifestyle Modification ◽  
Apnea Hypopnea Index ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Obstructive Sleep ◽  
Objective Evidence

Background: Lifestyle modification is the mainstay therapy for obese patients with obstructive sleep apnea (OSA). However, most of these patients are unable to lose the necessary weight, and bariatric surgery (BS) has been proven to be an effective modality in selected cases. Objective: To provide objective evidence that BS can improve OSA severity. Materials and Methods: A prospective study was conducted in super morbidly obese patients (body mass index [BMI] greater than 40 kg/m² or BMI greater than 35 kg/m² with uncontrolled comorbidities) scheduled for BS. Polysomnography (PSG) was performed for preoperative assessment and OSA was treated accordingly. After successful surgery, patients were invited to perform follow-up PSG at 3, 6, and 12 months. Results: Twenty-four patients with a mean age of 35.0±14.0 years were enrolled. After a mean follow-up period of 7.8±3.4 months, the mean BMI, Epworth sleepiness scale (ESS), and apnea-hypopnea index (AHI) significantly decreased from 51.6±8.7 to 38.2±6.8 kg/m² (p<0.001), from 8.7±5.9 to 4.7±3.5 (p=0.003), and from 87.6±38.9 to 28.5±21.5 events/hour (p<0.001), respectively. Conclusion: BS was shown to dramatically improve clinical and sleep parameters in super morbidly obese patients. Keywords: Morbid obesity, Bariatric surgery, Obstructive sleep apnea (OSA)

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