scholarly journals Worlds Beyond: A Strategy for the Detection and Characterization of Exoplanets Executive Summary of a Report of the ExoPlanet Task Force Astronomy and Astrophysics Advisory Committee Washington, DC June 23, 2008

Astrobiology ◽  
2008 ◽  
Vol 8 (5) ◽  
pp. 875-881 ◽  
Author(s):  
Jonathan I. Lunine ◽  
Debra Fischer ◽  
H.B. Hammel ◽  
Thomas Henning ◽  
Lynne Hillenbrand ◽  
...  
2012 ◽  
Vol 18 (8) ◽  
pp. 1074-1080 ◽  
Author(s):  
D Ontaneda ◽  
N LaRocca ◽  
T Coetzee ◽  
RA Rudick

This article describes proceedings from a meeting of the National Multiple Sclerosis Society (NMSS) Task Force on Clinical Disability Measures (the TF). The TF was appointed by the NMSS Research Programs Advisory Committee with the goal of pooling and analyzing existing datasets to explore the utility of novel disability outcome measures based on the Multiple Sclerosis Functional Composite (MSFC) approach. The TF seeks to determine the suitability of the MSFC approach as a primary clinical outcome measure for registration trials in MS. The TF met in Washington, DC, Dec. 14 and 15, 2011, and provided unanimous support for a collaborative approach involving representatives from academic medicine, the pharmaceutical industry, regulatory agencies, the NMSS and the Critical Path Institute. There was also unanimous agreement that analysis of existing datasets would be useful in making progress toward the objective. The TF placed high value on determining the clinical meaning of individual component measures for the MSFC, and in establishing optimal analysis methods for MSFC so that scores would be more interpretable than the originally recommended z-score method. The background for a collaborative project aimed at developing an improved disability outcome measure is described in this paper.


Author(s):  
Brittany Wilbourn ◽  
Brittani Saafir-Callaway ◽  
Kamwing Jair ◽  
Joel O Wertheim ◽  
Oliver Laeyendecker ◽  
...  

2011 ◽  
pp. 1016-1046
Author(s):  
Douglas Holmes

This chapter was prepared originally for the 2002 Task Force of the OECD Project on the Impact of E-Government and was updated in 2004 for inclusion in the book, Practicing E-Government: A Global Perspective. The chapter addresses the risk of low public awareness and declining political interest as barriers to e-government, and considers ways governments can develop better marketing techniques to “sell” online services and the e-government concept to both groups. The term “marketing” is used loosely to mean both the presentation and promotion of actual online services to encourage people to use them, and the presentation and promotion of the theory and concept of e-government to ensure political understanding of its benefits to society. The chapter has two parts plus an initial Executive Summary that summarizes the points raised in both sections. Part A discusses demand-side issues: the lack of awareness and confusion among users and potential users of electronic services and how these issues can be addressed with various marketing techniques. While the greatest factor contributing to low take-up of electronic services continues to be poor Internet access and a lack of computer skills, the purpose of this report is not to address social exclusion issues. It is recognized that the digital divide is gradually being bridged and therefore the chapter primarily considers the person who has access to a computer but, for a variety of reasons, does not use it to access government services. Part B looks at the supply side and ways to market the concept of e-government to decision-makers — politicians and senior level bureaucrats — who are responsible for supporting and funding the development of online services and for removing remaining regulatory and legal barriers. The chapter does not address culture change within the public sector and the need to shift the mindset of government employees from traditional department-centric thinking into more customer-centric and user-friendly approaches. Overcoming employee resistance to new working methods requires more management skills than marketing skills. But marketing techniques can be used to address the risk of a backlash against e-government as declining political interest in the Internet generally and in e-government specifically coincides with the need to develop more complex and expensive electronic services and information systems. The author would like to thank Stefan Czerniawski, David Hickman, Chris Roberts, and Rod Quiney for their contributions.


2002 ◽  
Vol 96 (1) ◽  
pp. 219-220
Author(s):  
Karen M. Kedrowski

The essays in this short volume address three themes: the characterization of political campaign television advertising, the need to measure its effects, and the role and implications of issue advertising. This is an ambitious agenda, but the book makes some important contributions to the literature on campaigns and on political ads specifically.


Neurosurgery ◽  
2019 ◽  
Vol 85 (3) ◽  
pp. 299-301 ◽  
Author(s):  
Catherine A Mazzola ◽  
Nadege Assassi ◽  
Lissa C Baird ◽  
David F Bauer ◽  
Alexandra D Beier ◽  
...  

Abstract BACKGROUND The incidence of spina bifida (SB) in the developing world is higher than in the United States because of malnutrition and folic acid deficiency during pregnancy. Advances in technology have made prenatal repair of myelomeningocele (MM) possible. OBJECTIVE The objective of the guidelines are, (1) To create clinical recommendations for best practices, based on a systematic review and analysis of available literature, (2) to obtain multi-disciplinary endorsement of these guidelines from relevant organizations, and (3) to disseminate the educational content to physicians to improve the care of infants with MM. METHODS The Guidelines Task Force developed search terms and strategies used to search PubMed and Embase for literature published between 1966 and September 2016. Strict inclusion/exclusion criteria were used to screen abstracts and to develop a list of relevant articles for full-text review. RESULTS Guidelines authors aimed to systematically review the literature and make evidence based recommendations about the timing of closure after birth, hydrocephalus, the impact of prenatal closure, and the effect of prenatal closure on ambulation ability and tethered spinal cord. Evidence concerning persistent ventriculomegaly and cognitive impairment was also evaluated. Hundreds of abstracts were identified and reviewed for each of the 5 topics. A total of 14 studies met stringent inclusion criteria. CONCLUSION Based on a comprehensive systematic review, a total of 5 clinical practice recommendations were developed, with 1 Level I, 2 Level II and 2 Level III recommendations. The full guideline can be found at https://www.cns.org/guidelines/guidelines-spina-bifida-chapter-1.


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