Proximal Renal Tubular Dysfunction Related to Antiretroviral Therapy Among HIV-Infected Patients in an HIV Clinic in Mexico

2015 ◽  
Vol 29 (4) ◽  
pp. 181-185 ◽  
Author(s):  
Karen Andrade-Fuentes ◽  
José A. Mata-Marín ◽  
José I. López-De León ◽  
Bulmaro Manjarrez-Téllez ◽  
Jorge L. Sandoval Ramírez ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Tubular Dysfunction ◽  
Renal Tubular Dysfunction ◽  
Proximal Renal Tubular Dysfunction ◽  
Renal Tubular

Proximal Renal Tubular Dysfunction in Severe Burns

1984 ◽  
Vol 4 (1) ◽  
pp. 44-47 ◽  
Author(s):  
John Lindquist ◽  
Charles Drueck ◽  
Norman M. Simon ◽  
Bruce Elson ◽  
Dan Hurwich ◽  
...  
Keyword(s):  
Tubular Dysfunction ◽  
Renal Tubular Dysfunction ◽  
Severe Burns ◽  
Proximal Renal Tubular Dysfunction ◽  
Renal Tubular

Acquired Proximal Renal Tubular Dysfunction in β-Thalassemia Patients Treated With Deferasirox

2010 ◽  
Vol 32 (7) ◽  
pp. 564-567 ◽  
Author(s):  
Joanne Yacobovich ◽  
Pinhas Stark ◽  
Shlomit Barzilai-Birenbaum ◽  
Irit Krause ◽  
Idit Pazgal ◽  
...  
Keyword(s):  
Tubular Dysfunction ◽  
Renal Tubular Dysfunction ◽  
Proximal Renal Tubular Dysfunction ◽  
Renal Tubular

scholarly journals Reversal of Proximal Renal Tubular Dysfunction after Nucleotide Analogue Withdrawal in Chronic Hepatitis B

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Abhasnee Sobhonslidsuk ◽  
Pawin Numthavaj ◽  
Jirachaya Wanichanuwat ◽  
Areepan Sophonsritsuk ◽  
Supanna Petraksa ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Fractional Excretion ◽  
Tubular Dysfunction ◽  
Renal Tubular Dysfunction ◽  
Nucleotide Analogue ◽  
Proximal Renal Tubular Dysfunction ◽  
Renal Tubular ◽  
One Year

Aims. Proximal renal tubular dysfunction (PRTD) is an infrequent complication after nucleotide analogue therapy. We evaluated the outcomes of PRTD and nephrotoxicity after nucleotide analogue withdrawal in chronic hepatitis B (CHB). Methods. A longitudinal follow-up study was performed in patients with PRTD after nucleotide analogue discontinuation. Serum and urine were collected at baseline and every 3 months for one year. The fractional excretion of phosphate (PO4), uric acid (UA), and potassium and tubular maximal reabsorption rate of PO4 to glomerular filtration rate (TmPO4/GFR) were calculated. Renal losses were defined based on the criteria of substance losses. Subclinical PRTD and overt PRTD were diagnosed when 2 and ≥3 criteria were identified. Results. Eight subclinical and eight overt PRTD patients were enrolled. After nucleotide analogue withdrawal, there were overall improvements in GFR, serum PO4, and UA. Renal loss of PO4, UA, protein, and β2-microglobulin reduced over time. At one year, complete reversal of PRTD was seen in 13 patients (81.2%). Improvements in PRTD were seen in all but one patient. Conclusion. One year after nucleotide analogue withdrawal, PRTD was resolved in most patients. Changes in TmPO4/GFR, urinary protein, and β2-microglobulin indicate that urinary biomarkers may represent an early sign of PRTD recovery.

scholarly journals Reversible Proximal Renal Tubular Dysfunction after One-Time Ifosfamide Exposure

2010 ◽  
Vol 42 (4) ◽  
pp. 244 ◽  
Author(s):  
Young Il Kim ◽  
Ju Young Yoon ◽  
Jun Eul Hwang ◽  
Hyun Jeong Shim ◽  
Woo Kyun Bae ◽  
...  
Keyword(s):  
Tubular Dysfunction ◽  
Renal Tubular Dysfunction ◽  
Proximal Renal Tubular Dysfunction ◽  
Renal Tubular
Sign in / Sign up

Export Citation Format

Share Document