scholarly journals Antiretroviral Treatment Interruption and Loss to Follow-Up in Two HIV Cohorts in Australia and Asia: Implications for ‘Test and Treat’ Prevention Strategy

2013 ◽  
Vol 27 (12) ◽  
pp. 681-691 ◽  
Author(s):  
Rebecca Guy ◽  
Handan Wand ◽  
Hamish McManus ◽  
Saphonn Vonthanak ◽  
Ian Woolley ◽  
...  
Keyword(s):  
Antiretroviral Treatment ◽  
Treatment Interruption ◽  
Prevention Strategy ◽  
Loss To Follow Up ◽  
Test And Treat

scholarly journals Predictors of virological failure among people living with HIV receiving first line antiretroviral treatment in Myanmar: retrospective cohort analysis

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Anita Mesic ◽  
Alexander Spina ◽  
Htay Thet Mar ◽  
Phone Thit ◽  
Tom Decroo ◽  
...  
Keyword(s):  
Viral Load ◽  
Virological Failure ◽  
Antiretroviral Treatment ◽  
People Living With Hiv ◽  
First Line ◽  
Hiv Viral Load ◽  
Loss To Follow Up ◽  
History Of ◽  
Living With Hiv

Abstract Background Progress toward the global target for 95% virological suppression among those on antiretroviral treatment (ART) is still suboptimal. We describe the viral load (VL) cascade, the incidence of virological failure and associated risk factors among people living with HIV receiving first-line ART in an HIV cohort in Myanmar treated by the Médecins Sans Frontières in collaboration with the Ministry of Health and Sports Myanmar. Methods We conducted a retrospective cohort study, including adult patients with at least one HIV viral load test result and having received of at least 6 months’ standard first-line ART. The incidence rate of virological failure (HIV viral load ≥ 1000 copies/mL) was calculated. Multivariable Cox’s regression was performed to identify risk factors for virological failure. Results We included 25,260 patients with a median age of 33.1 years (interquartile range, IQR 28.0–39.1) and a median observation time of 5.4 years (IQR 3.7–7.9). Virological failure was documented in 3,579 (14.2%) participants, resulting in an overall incidence rate for failure of 2.5 per 100 person-years of follow-up. Among those who had a follow-up viral load result, 1,258 (57.1%) had confirmed virological failure, of which 836 (66.5%) were switched to second-line treatment. An increased hazard for failure was associated with age ≤ 19 years (adjusted hazard ratio, aHR 1.51; 95% confidence intervals, CI 1.20–1.89; p < 0.001), baseline tuberculosis (aHR 1.39; 95% CI 1.14–1.49; p < 0.001), a history of low-level viremia (aHR 1.60; 95% CI 1.42–1.81; p < 0.001), or a history of loss-to-follow-up (aHR 1.24; 95% CI 1.41–1.52; p = 0.041) and being on the same regimen (aHR 1.37; 95% CI 1.07–1.76; p < 0.001). Cumulative appointment delay was not significantly associated with failure after controlling for covariates. Conclusions VL monitoring is an important tool to improve programme outcomes, however limited coverage of VL testing and acting on test results hampers its full potential. In our cohort children and adolescents, PLHIV with history of loss-to-follow-up or those with low-viremia are at the highest risk of virological failure and might require more frequent virological monitoring than is currently recommended.

scholarly journals Medication Possession Ratio: Predicting and Decreasing Loss to Follow-Up in Antiretroviral Treatment Programs in Côte dʼIvoire

2011 ◽  
Vol 57 ◽  
pp. S34-S39 ◽  
Author(s):  
Eugène Messou ◽  
Martial Kouakou ◽  
Delphine Gabillard ◽  
Patrice Gouessé ◽  
Mamadou Koné ◽  
...  
Keyword(s):  
Antiretroviral Treatment ◽  
Medication Possession Ratio ◽  
Treatment Programs ◽  
Loss To Follow Up

scholarly journals Male, Mobile, and Moneyed: Loss to Follow-Up vs. Transfer of Care in an Urban African Antiretroviral Treatment Clinic

PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e78900 ◽  
Author(s):  
Kara G. Marson ◽  
Kenneth Tapia ◽  
Pamela Kohler ◽  
Christine J. McGrath ◽  
Grace C. John-Stewart ◽  
...  
Keyword(s):  
Antiretroviral Treatment ◽  
Transfer Of Care ◽  
Loss To Follow Up ◽  
Treatment Clinic

scholarly journals Predictors of Loss to Follow-up in Patients on Antiretroviral Treatment in Centre Hospitalier Essos, Cameroon

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Agbor Agbornkwai Nyenty ◽  
Gael Bita Andre Izacar ◽  
Brian Ajong ◽  
Stanislas Ateh ◽  
Stephane MabounaAmatangana ◽  
...  
Keyword(s):  
Antiretroviral Treatment ◽  
Loss To Follow Up ◽  
Centre Hospitalier

scholarly journals Predictors of loss to follow-up in antiretroviral treatment for adult patients in the Oromia region, Ethiopia

2016 ◽  
pp. 83 ◽  
Author(s):  
Abebe Megerso ◽  
Sileshi Garoma ◽  
Tolesa Eticha ◽  
Tilaye Workineh ◽  
Shallo Daba ◽  
...  
Keyword(s):  
Antiretroviral Treatment ◽  
Adult Patients ◽  
Loss To Follow Up

Early loss to follow-up and mortality of HIV-infected patients diagnosed after the era of antiretroviral treatment scale up: a call for re-invigorating the response in Iran

2013 ◽  
Vol 24 (12) ◽  
pp. 926-930 ◽  
Author(s):  
Banafsheh Moradmand Badie ◽  
Ghaemeh Nabaei ◽  
Mehrnaz Rasoolinejad ◽  
Ali Mirzazadeh ◽  
Willi McFarland
Keyword(s):  
Antiretroviral Treatment ◽  
Scale Up ◽  
Loss To Follow Up ◽  
Early Loss
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