scholarly journals Augmenting Intralesional Collagenase Treatment with Testosterone Therapy Provides Greater Self-Assessed Improvement in Penile Curvature due to Peyronie's Disease

2020 ◽  
Vol 1 (1) ◽  
pp. 70-75
Author(s):  
Nadezhda Shlykova ◽  
Abraham Morgentaler
Keyword(s):  
Peyronie’S Disease ◽  
Penile Curvature ◽  
Testosterone Therapy ◽  
Collagenase Treatment ◽  
Peyronie's Disease

Initial experience in the treatment of Peyronie’s disease using testicular vaginal tunica graft

2021 ◽  
pp. 205141582110166
Author(s):  
Rico Luis ◽  
Villasante Nicolás ◽  
Blas Leandro ◽  
Bonnano Nicolás ◽  
Ameri Carlos
Keyword(s):  
Sexual Function ◽  
Tunica Albuginea ◽  
Peyronie’S Disease ◽  
Sexual Life ◽  
Rank Test ◽  
Penile Curvature ◽  
Initial Experience ◽  
Level Of Evidence ◽  
Paired Samples ◽  
Peyronie's Disease

Background: Peyronie’s disease (PD) is a progressive disorder of the connective tissue of the tunica albuginea of the penis that produces an abnormal curvature, painful erections and different degrees of erectile dysfunction (ED). The aim of this study is to evaluate our initial experience in the surgical treatment of PD using an autologous graft of testicular vaginal tunica. Materials and methods: A retrospective study of 23 patients was carried out between 2015 and 2019. The successful surgical stretching rate was defined as a functional 20 degrees of curvature or less. Postoperative sexual function and complications rate were evaluated as secondary objectives. We used the abbreviated IIEF-5 questionnaire and evaluated the sexual function before and after the surgical procedure. Wilcoxon signed-rank test for paired samples (U test) was used, considering a value of p<0.05 to be statistically significant. Results: Only one patient presented a recurrence of the penile curvature, resulting in a 95.6% success rate of functional stretching. We observed a 1.6 and 0.9 difference between pre- and postoperative total score and satisfaction ( p = 0.002 and p = 0.003 respectively) Conclusion: In this series, the use of testicular vaginal tunic was found to be safe and effective with a significant change in the quality of sexual life, especially reflected in the overall satisfaction after the procedure and a low rate of complications. Level of evidence: Not applicable for this multicentre audit.

Relationship Between the Severity of Penile Curvature and the Presence of Comorbidities in Men With Peyronie's Disease

2004 ◽  
Vol 171 (2) ◽  
pp. 775-779 ◽  
Author(s):  
MUSTAFA F. USTA ◽  
TRINITY J. BIVALACQUA ◽  
GEORGE W. JABREN ◽  
LEANN MYERS ◽  
JOSE SANABRIA ◽  
...  
Keyword(s):  
Peyronie’S Disease ◽  
Penile Curvature ◽  
Peyronie's Disease

scholarly journals Tunical plication in the management of penile curvature due La Peyronie’s disease. Our experience on 47 cases

BMC Surgery ◽  
2012 ◽  
Vol 12 (Suppl 1) ◽  
pp. S25 ◽  
Author(s):  
Fabrizio Iacono ◽  
Domenico Prezioso ◽  
Antonio Ruffo ◽  
Ester Illiano ◽  
Giuseppe Romeo ◽  
...  
Keyword(s):  
Peyronie’S Disease ◽  
Penile Curvature ◽  
La Peyronie’S Disease ◽  
Peyronie's Disease

A clinico-aetiological and ultrasonographic study of Peyronie's disease

Sexual Health ◽  
2006 ◽  
Vol 3 (2) ◽  
pp. 113 ◽  
Author(s):  
Bhushan Kumar ◽  
Tarun Narang ◽  
Somesh Gupta ◽  
Madhu Gulati
Keyword(s):  
Clinical Presentation ◽  
Clinical Symptoms ◽  
Tunica Albuginea ◽  
Connective Tissue Disorder ◽  
Peyronie’S Disease ◽  
Penile Curvature ◽  
Age Group ◽  
History Of ◽  
Peyronie's Disease ◽  
Symptoms And Signs

Background: Peyronie’s disease is a localised connective tissue disorder that involves the tunica albuginea of the penis. Although long recognised as an important clinical entity of the male genitalia, the aetiology of this disease has remained poorly understood. Methods: The epidemiology and clinical presentation of Peyronie’s disease during a 10-year period was evaluated. Results: Forty-two men with Peyronie’s disease from Chandigarh, India were reviewed retrospectively. The prevalence of Peyronie’s patients was 1.97/1000 patients. Their ages ranged from 23 to 70 years. Most of them presented during the early phase of the disease. The most common presenting complaint was penile curvature in 34 (80.95%) followed by pain on erection in 28 (66.66%). History of penile trauma was revealed by four (9.52%) patients. Among the risk factors, hypercholesterolemia (60%), hypertension (33.3%) and asymptomatic hyperuricemia (28.34%) were the most common. Twenty-two patients with Peyronie’s disease were studied by ultrasonography. Ultrasonogram was more accurate than clinical assessment in delineating the extent of lesions. In one-third of the patients, sonography demonstrated the plaques to be more extensive than had been detected by clinical examination. Conclusions: The clinical symptoms and signs in our study were, in general, similar to those found in the previous studies. Higher incidence of hypertension and diabetes in patients with Peyronie’s disease may also be to an extent due to patients being in an older age group.

Heterologous Dermal Graft (Alloderm) after Plaque Excision in Peyronie'S Disease. First Experience

1998 ◽  
Vol 65 (1_suppl) ◽  
pp. 28-30
Author(s):  
M. Paradiso ◽  
O. Sedigh ◽  
A. Formiconi ◽  
A. Volpe ◽  
U. Ferrando ◽  
...  
Keyword(s):  
Clinical Study ◽  
Surgical Techniques ◽  
Peyronie’S Disease ◽  
Penile Curvature ◽  
Synthetic Material ◽  
Dermal Matrix ◽  
Dermal Graft ◽  
Biopsy Specimens ◽  
Peyronie's Disease

Several reconstructive surgical techniques have been developed for correction of penile curvature in Peyronie's disease. In some cases plaque excision and grafting with various autologous tissues or synthetic material are performed. Autologous dermal graft is the most commonly used. Today a cadaveric dermal allograft as fully decellularized dermal matrix is available (AlloDerm). This clinical study evaluated the capacity of AlloDerm allograft dermal matrix to function as a permanent dermal transplant and potentially enhance the quality of grafts applied to penile albuginea defect after plaque excision in five patients with Peyronie's disease. Biopsy specimens were obtained from 2 patients at 4 months to test revascularization and adherence of the graft.

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