Identification of a Novel HIV-1 Unique Recombinant Form Comprising CRF01_AE, Subtype B’, and CRF65_cpx Among Men Who Have Sex with Men in Jilin, China

2018 ◽  
Vol 34 (8) ◽  
pp. 714-718 ◽  
Author(s):  
Yuan-Long Lin ◽  
Bo Song ◽  
Bing Shao ◽  
Si-Yu Liu ◽  
Qing-Qing Huo ◽  
...  
Keyword(s):  
Recombinant Form ◽  
Subtype B ◽  
Unique Recombinant Form ◽  
Sex With Men ◽  
Hiv 1

Identification of a Novel HIV-1 Unique Recombinant Form Between B, CRF01_AE and CRF07_BC in Men Who Have Sex with Men in Guangxi, China

2018 ◽  
Vol 34 (3) ◽  
pp. 319-323 ◽  
Author(s):  
Desheng Kong ◽  
Yan Wang ◽  
Chen Wang ◽  
Shujia Liang ◽  
Yi Feng ◽  
...  
Keyword(s):  
Recombinant Form ◽  
Unique Recombinant Form ◽  
Sex With Men ◽  
Hiv 1

scholarly journals Characterization of a novel HIV-1 unique recombinant form between CRF07_BC and CRF55_01B in men who have sex with men in Guangzhou, China

PLoS ONE ◽  
2017 ◽  
Vol 12 (4) ◽  
pp. e0175770 ◽  
Author(s):  
Yue Wu ◽  
Xuqi Ren ◽  
Dan Yin ◽  
Haiying Wang ◽  
Zhengwei Wan ◽  
...  
Keyword(s):  
Recombinant Form ◽  
Unique Recombinant Form ◽  
Sex With Men ◽  
Hiv 1

scholarly journals Genome Sequence of a Complex HIV-1 Unique Recombinant Form Involving CRF01_AE, Subtype B, and Subtype B' Identified in Malaysia

2014 ◽  
Vol 2 (2) ◽  
Author(s):  
W. Z. Chow ◽  
S. Nizam ◽  
L. Y. Ong ◽  
K. T. Ng ◽  
K. G. Chan ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Recombinant Form ◽  
Subtype B ◽  
Unique Recombinant Form ◽  
Hiv 1

Genetic characterization of a novel unique recombinant form of HIV-1 originating from subtype A1 and C in Guangdong Province, China

2018 ◽  
Vol 164 (1) ◽  
pp. 285-290 ◽  
Author(s):  
Haohui Deng ◽  
Shuzhen Liang ◽  
Huiyuan Liu ◽  
Min Xu ◽  
Li Zhuo ◽  
...  
Keyword(s):  
Genetic Characterization ◽  
Guangdong Province ◽  
Recombinant Form ◽  
Unique Recombinant Form ◽  
Hiv 1

scholarly journals New Subtype B Containing HIV-1 Circulating Recombinant of sub-Saharan Africa Origin in Nigerian Men Who Have Sex With Men

2019 ◽  
Vol 81 (5) ◽  
pp. 578-584 ◽  
Author(s):  
Erik Billings ◽  
Gustavo H. Kijak ◽  
Eric Sanders-Buell ◽  
Nicaise Ndembi ◽  
Anne Marie OʼSullivan ◽  
...  
Keyword(s):  
Sub Saharan Africa ◽  
Subtype B ◽  
Nigerian Men ◽  
Sub Saharan ◽  
Sex With Men ◽  
Hiv 1

scholarly journals Molecular epidemiology of HIV-1 infection in immigrant population in northern Italy

2020 ◽  
Vol 148 ◽  
Author(s):  
Caterina Sagnelli ◽  
Caterina Uberti-Foppa ◽  
Sabrina Bagaglio ◽  
Eleonora Cella ◽  
Vittoria Scolamacchia ◽  
...  
Keyword(s):  
Phylogenetic Tree ◽  
Molecular Epidemiology ◽  
Northern Italy ◽  
Subtype B ◽  
Immunodeficiency Virus ◽  
Male Patients ◽  
Sub Saharan ◽  
Sex With Men ◽  
Cd4 Cell ◽  
Hiv 1

Abstract Human immunodeficiency virus-1 (HIV-1) is characterised by a vast genetic diversity classified into distinct phylogenetic strains and recombinant forms. We describe the HIV-1 molecular epidemiology and evolution of 129 consecutive HIV-1 positive migrants living in Milan (northern Italy). Polymerase gene sequences of 116 HIV-1 subtype-B positive patients were aligned with HIV-1 reference sequences (https://www.ncbi.nlm.nih.gov/) by using MAFFT alignment and edited by using Bioedit software. A maximum likelihood (ML) phylogenetic tree was performed by MEGA7 and was visualised by using FigTree v1.4.3. Of 129 migrants, 35 were born in Europe (28 in Eastern Europe), 70 in the Americas (67 in South America), 15 in Africa and nine in Asia; 76.4% were men who have sex with men (MSM). The serotype HIV-1-B prevailed (89.9%), followed by -C, -F1, -D and -A. Compared with 116 HIV-B patients, the 13 with HIV-non-B showed lower Nadir of CD4+ cell/mmc (P = 0.043), more frequently had sub Saharan origin (38.5 vs. 1.72%, P = 0.0001) and less frequently were MSM (40 vs. 74.5%, P = 0.02). The ML phylogenetic tree of the 116 HIV-1 subtype-B positive patients showed 13 statistically supported nodes (bootstrap > 70%). Most of the sequences included in these nodes have been isolated from male patients from the Americas and the most common risk factor was MSM. The low number of HIV-1 non-B subtype patients did not allow to perform this analysis. These results suggest a shift of HIV-1 prevention projects' focus and a continuous monitoring of HIV-1 molecular epidemiology among entry populations. Prevention efforts based on HIV molecular epidemiology may improve public health surveillance setting.

scholarly journals Evolutionary History of HIV-1 Subtype B and CRF01_AE Transmission Clusters among Men Who Have Sex with Men (MSM) in Kuala Lumpur, Malaysia

PLoS ONE ◽  
2013 ◽  
Vol 8 (6) ◽  
pp. e67286 ◽  
Author(s):  
Kim Tien Ng ◽  
Lai Yee Ong ◽  
Sin How Lim ◽  
Yutaka Takebe ◽  
Adeeba Kamarulzaman ◽  
...  
Keyword(s):  
Evolutionary History ◽  
Kuala Lumpur ◽  
Subtype B ◽  
History Of ◽  
Sex With Men ◽  
Hiv 1

scholarly journals A Recent Outbreak of Human Immunodeficiency Virus Type 1 Infection in Southern China Was Initiated by Two Highly Homogeneous, Geographically Separated Strains, Circulating Recombinant Form AE and a Novel BC Recombinant

2000 ◽  
Vol 74 (23) ◽  
pp. 11286-11295 ◽  
Author(s):  
Sucheep Piyasirisilp ◽  
Francine E. McCutchan ◽  
Jean K. Carr ◽  
Eric Sanders-Buell ◽  
Wei Liu ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Southern China ◽  
Recombinant Form ◽  
Subtype C ◽  
Subtype B ◽  
Immunodeficiency Virus ◽  
Hiv 1

ABSTRACT New outbreaks of human immunodeficiency virus type 1 (HIV-1) among injecting drug users (IDUs) are spreading in China along heroin trafficking routes. Recently, two separate HIV-1 epidemics among IDUs were reported in Guangxi, Southern China, where partial sequencing of the env gene showed subtype C and circulating recombinant form (CRF) AE. We evaluated five virtually full-length HIV-1 genome sequences from IDUs in Guangxi to determine the genetic diversity and the presence of intersubtype recombinants. Sequence analysis showed two geographically separated, highly homogeneous HIV-1 strains. B/C intersubtype recombinants were found in three IDUs from Baise City, in a mountainous region near the Yunnan-Guangxi border. These were mostly subtype C, with portions of the capsid and reverse transcriptase (RT) genes from subtype B. The subtype B portion of the capsid was located in the N-terminal domain, which has been shown to influence virus core maturation, virus infectivity, and binding to cyclophilin A, whereas the subtype B portion of RT was located in the palm subdomain, which is the active site of the enzyme. These BC recombinants differed from a BC recombinant found in Xinjiang Province in northwestern China. CRF AE strains were found in IDUs from Nanning, the capital of Guangxi, and in IDUs from Pingxiang City near the China-Vietnam border. The AE and BC recombinants were both remarkable for their low interpatient diversity, less than 1% for the full genome. Rapid spread of HIV-1 among IDUs may foster the emergence of highly homogeneous strains, including novel recombinants in regions with multiple subtypes.

scholarly journals Identification and Characterization of a Novel HIV-1 Circulating Recombinant Form (CRF59_01B) Identified among Men-Who-Have-Sex-with-Men in China

PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e99693 ◽  
Author(s):  
Weiqing Zhang ◽  
Xiaoxu Han ◽  
Minghui An ◽  
Bin Zhao ◽  
Qinghai Hu ◽  
...  
Keyword(s):  
Recombinant Form ◽  
Sex With Men ◽  
Identification And Characterization ◽  
Hiv 1
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