Characterization of Envelope Surface Glycoprotein from HIV-2 Primary Isolates with Different Coreceptor Usage Profile

2018 ◽  
Vol 34 (2) ◽  
pp. 218-221
Author(s):  
Paula Cerejo ◽  
Quirina Santos-Costa ◽  
Marta Calado ◽  
Maria Espírito-Santo ◽  
Ricardo Parreira ◽  
...  
Keyword(s):  
Surface Glycoprotein ◽  
Coreceptor Usage ◽  
Envelope Surface

Enhancement of EIAV Replication and Disease by Immunization with a Baculovirus-Expressed Recombinant Envelope Surface Glycoprotein

Virology ◽  
1994 ◽  
Vol 199 (1) ◽  
pp. 247-251 ◽  
Author(s):  
S.Z.-S. Wang ◽  
K.E. Rushlow ◽  
C.J. Issel ◽  
R.F. Cook ◽  
S.J. Cook ◽  
...  
Keyword(s):  
Surface Glycoprotein ◽  
Envelope Surface

Characterization of VSG gene expression site promoters and promoter-associated DNA rearrangement events

1991 ◽  
Vol 11 (5) ◽  
pp. 2467-2480 ◽  
Author(s):  
K Gottesdiener ◽  
H M Chung ◽  
S D Brown ◽  
M G Lee ◽  
L H Van der Ploeg
Keyword(s):  
Transcriptional Control ◽  
Transcription Unit ◽  
Surface Glycoprotein ◽  
Dna Rearrangement ◽  
Cell Surface Glycoprotein ◽  
Polycistronic Transcription ◽  
Variant Cell ◽  
Expression Site ◽  
Simple Sequence

The expressed variant cell surface glycoprotein (VSG) gene of Trypanosoma brucei is located at the 3' end of a large, telomeric, polycistronic transcription unit or expression site. We show that the region 45 kb upstream of the VSG gene, in the expression site on a 1.5-Mb chromosome, contains at least two promoters that are arranged in tandem, directing the transcription of the expression site. DNA rearrangement events occur specifically, at inactivation of the expression site, and these events delete the most upstream transcribed region and replace it with a large array of simple-sequence DNA, leaving the downstream promoter intact. Because of the placement of simple-sequence DNA, the remaining downstream promoter now becomes structurally identical to previously described VSG promoters. The downstream promoter is repetitive in the genome, since it is present at several different expression sites. Restriction fragment length polymorphism mapping allows grouping of the expression sites into two families, those with and those without an upstream transcription unit, and the DNA rearrangement events convert the expression sites from one type to the other. Deletion of the upstream transcription unit also leads to the loss of several steady-state RNAs. The findings may indicate a role for promoter-associated DNA rearrangement events, and/or interactions between tandemly arranged promoters, in expression site transcriptional control.

Expression and Characterization of a cDNA Clone Encoding an Immunodominant Surface Glycoprotein of Pneumocystis carinii

1992 ◽  
Vol 166 (5) ◽  
pp. 1113-1123 ◽  
Author(s):  
P. J. Haidaris ◽  
T. W. Wright ◽  
F. Gigliotti ◽  
C. G. Haidaris
Keyword(s):  
Cdna Clone ◽  
Pneumocystis Carinii ◽  
Surface Glycoprotein

Characterization of a major fibroblast cell surface glycoprotein

Biochemistry ◽  
1977 ◽  
Vol 16 (25) ◽  
pp. 5552-5559 ◽  
Author(s):  
Kenneth M. Yamada ◽  
David H. Schlesinger ◽  
Dorothy W. Kennedy ◽  
Ira Pastan
Keyword(s):  
Cell Surface ◽  
Fibroblast Cell ◽  
Surface Glycoprotein ◽  
Cell Surface Glycoprotein
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