CRF01_AE/B/C, a Novel Drug-Resistant HIV-1 Recombinant in Men Who Have Sex with Men in Beijing, China

2015 ◽  
Vol 31 (7) ◽  
pp. 745-748 ◽  
Author(s):  
Jing Yan ◽  
Ruolei Xin ◽  
Zheng Li ◽  
Yi Feng ◽  
Hongyan Lu ◽  
...  
Keyword(s):  
Drug Resistant ◽  
Sex With Men ◽  
Novel Drug ◽  
Beijing China ◽  
Hiv 1

The Dynamic Face of HIV-1 Subtypes Among Men who have Sex with Men in Beijing, China

2011 ◽  
Vol 9 (2) ◽  
pp. 136-139 ◽  
Author(s):  
Wanhai Wang ◽  
Jianqing Xu ◽  
Shulin Jiang ◽  
Kai Yang ◽  
Zhefeng Meng ◽  
...  
Keyword(s):  
Sex With Men ◽  
Beijing China ◽  
Hiv 1

Characterization of a Novel HIV-1 Second-Generation Recombinant Form in Men Who Have Sex with Men in Beijing, China

2017 ◽  
Vol 33 (11) ◽  
pp. 1175-1179 ◽  
Author(s):  
Chen Wang ◽  
Yan Wang ◽  
Desheng Kong ◽  
Ruolei Xin ◽  
Weisi Xu ◽  
...  
Keyword(s):  
Second Generation ◽  
Recombinant Form ◽  
Sex With Men ◽  
Beijing China ◽  
Hiv 1

scholarly journals Genomic Characterization of Two Novel HIV-1 Second-Generation Recombinant Forms Among Men Who Have Sex with Men in Beijing, China

2015 ◽  
Vol 31 (3) ◽  
pp. 342-346 ◽  
Author(s):  
Zheng Li ◽  
Huamian Wei ◽  
Yi Feng ◽  
Jia Li ◽  
Marcia L. Kalish ◽  
...  
Keyword(s):  
Second Generation ◽  
Genomic Characterization ◽  
Sex With Men ◽  
Beijing China ◽  
Hiv 1

Characterization of HIV-1 subtypes and viral antiretroviral drug resistance in men who have sex with men in Beijing, China

AIDS ◽  
2007 ◽  
Vol 21 (Suppl 8) ◽  
pp. S59-S65 ◽  
Author(s):  
Xiaoyan Zhang ◽  
Shenwei Li ◽  
Xinping Li ◽  
Xinxu Li ◽  
Jianqing Xu ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Drug Resistance ◽  
Antiretroviral Drug ◽  
Sex With Men ◽  
Beijing China ◽  
Hiv 1

scholarly journals Prevalence of GB virus type C viraemia in MSM with or without HIV-1 infection in Beijing, China

2012 ◽  
Vol 140 (12) ◽  
pp. 2199-2209 ◽  
Author(s):  
Z. LIU ◽  
L. LI ◽  
Z. CHEN ◽  
M. XU ◽  
T. ZHANG ◽  
...  
Keyword(s):  
Virus Type ◽  
Acute Stage ◽  
Genotype 3 ◽  
Chronic Stage ◽  
Viral Loads ◽  
Cell Counts ◽  
Sex With Men ◽  
Virus C ◽  
Beijing China ◽  
Hiv 1

SUMMARYGB virus C (GBV-C) is frequently identified in patients co-infected with human immunodeficiency virus type 1 (HIV-1) due to the similar transmission routes. However, it remains unclear how these two viruses interact with each other and how one virus affects the replication of the other in the human body. In this study, we performed a case-control study to determine whether GBV-C viraemia could prevent the acquisition of HIV-1 infection, and a cohort study to determine the prevalence, genotypic characteristics and incidence of GBV-C infection in men who have sex with men (MSM) populations in Beijing, China. The prevalence of GBV-C infection in HIV-1-negative subjects was similar to that in HIV-1-positive subjects. Before HIV-1 acquisition, the prevalence of GBV-C was 17·7%, which increased to 27·2% at the acute stage and to 34% at the chronic stage. Genotype 3 was the major genotype of GBV-C in both groups. A significantly positive correlation was observed between the CD4+ T-cell counts and GBV-C viral loads at the acute stage of HIV infection. At the chronic stage (12 months later), this correlation was no longer significant, although it was still positive. Overall, this study demonstrated that pre-existing GBV-C viraemia could not prevent the acquisition of HIV-1 infection and transmission of HIV-1 significantly increased the prevalence of GBV-C viraemia.

scholarly journals Transmission Cluster of Multiclass Highly Drug-Resistant HIV-1 Among 9 Men Who Have Sex With Men in Seattle/King County, WA, 2005-2007

2008 ◽  
Vol 49 (2) ◽  
pp. 205-211 ◽  
Author(s):  
Susan E Buskin ◽  
Giovanina M Ellis ◽  
Gregory G Pepper ◽  
Lisa M Frenkel ◽  
Steven A Pergam ◽  
...  
Keyword(s):  
King County ◽  
Drug Resistant ◽  
Sex With Men ◽  
Hiv 1

scholarly journals Characterisation of HIV-1 transmission clusters and drug-resistant mutations in Denmark, 2004 to 2016

2018 ◽  
Vol 23 (44) ◽  
Author(s):  
Andreas Petersen ◽  
Susan A Cowan ◽  
Jens Nielsen ◽  
Thea K Fischer ◽  
Jannik Fonager
Keyword(s):  
Drug Resistance ◽  
Drug Resistant ◽  
Resistance Mutations ◽  
Transmission Networks ◽  
Late Presenters ◽  
Drug Resistance Mutations ◽  
Hiv Epidemic ◽  
Immunodeficiency Virus ◽  
Sex With Men ◽  
Hiv 1

This study describes the prevalence of human immunodeficiency virus (HIV) drug resistance mutations among 1,815 patients in Denmark from 2004 to 2016 and characterises transmission clusters. POL sequences were analysed for subtype, drug resistance mutations and phylogenetic relationship. The prevalence of surveillance drug resistance mutations (SDRM) was 6.7%, while the prevalence of drug resistance mutations (DRM) with a clinical impact was 12.3%. We identified 197 transmission clusters with 706 patients. Patients 40 years or older were less likely to be members of a transmission cluster and patients in transmission clusters were less likely to be infected abroad. The proportion of late presenters (LP) was lower in active compared with inactive clusters. Large active clusters consisted of more men who have sex with men (MSM), had members more frequently infected in Denmark and contained a significantly lower proportion of LP and significantly fewer patients with DRM than small active clusters. Subtyping demonstrated that the Danish HIV epidemic is gradually becoming more composed of non-B subtypes/circulating recombinant forms. This study shows that active HIV-1 transmission has become increasingly MSM-dominated and that the recent increase in SDRM and DRM prevalence is not associated with more sustained transmission within identified transmission networks or clusters.

Identification of a Novel HIV-1 Second-Generation Recombinant Form (CRF01_AE/07_BC) in Men Who Have Sex with Men in Beijing, China

2019 ◽  
Vol 35 (5) ◽  
pp. 500-504 ◽  
Author(s):  
Mingqiang Hao ◽  
Juan Wang ◽  
Shufang He ◽  
Yinxiao Hao ◽  
Jingrong Ye ◽  
...  
Keyword(s):  
Second Generation ◽  
Recombinant Form ◽  
Sex With Men ◽  
Beijing China ◽  
Hiv 1

scholarly journals Genomic Characterization of Two Novel HIV-1 Unique (CRF01_AE/B) Recombinant Forms Among Men Who Have Sex with Men in Beijing, China

2015 ◽  
Vol 31 (9) ◽  
pp. 921-925 ◽  
Author(s):  
Zheng Li ◽  
Jia Li ◽  
Yi Feng ◽  
Marcia L. Kalish ◽  
Hongyan Lu ◽  
...  
Keyword(s):  
Genomic Characterization ◽  
Sex With Men ◽  
Beijing China ◽  
Hiv 1

A Unique Second-Generation Recombinant Form of HIV-1 Identified Among Men Who Have Sex with Men Population in Beijing, China

2017 ◽  
Vol 33 (10) ◽  
pp. 1070-1076 ◽  
Author(s):  
Xue Li ◽  
Mingqiang Hao ◽  
Yinxiao Hao ◽  
Jingrong Ye ◽  
Ruolei Xin ◽  
...  
Keyword(s):  
Second Generation ◽  
Recombinant Form ◽  
Sex With Men ◽  
Beijing China ◽  
Hiv 1
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