scholarly journals Foamy Virus in the Tree Shrew Tupaia Belangeri Is Highly Related to Simian Foamy Virus in Macaca Mulatta

2013 ◽  
Vol 29 (8) ◽  
pp. 1177-1178 ◽  
Author(s):  
Fen Huang ◽  
Wenhai Yu ◽  
Zhanlong He
Keyword(s):  
Macaca Mulatta ◽  
Tree Shrew ◽  
Foamy Virus ◽  
Simian Foamy Virus ◽  
Tupaia Belangeri

scholarly journals Novel Simian Foamy Virus infection of wild Indian rhesus macaque (Macaca mulatta)

Retrovirology ◽  
2011 ◽  
Vol 8 (S1) ◽  
Author(s):  
Jayashree S Nandi ◽  
Anil K Chhangani ◽  
Surendra M Mohnot
Keyword(s):  
Virus Infection ◽  
Rhesus Macaque ◽  
Macaca Mulatta ◽  
Foamy Virus ◽  
Simian Foamy Virus ◽  
Indian Rhesus Macaque

Transduction of Primate Cells with Feline Foamy Virus Envelope Pseudotyped Prototype Foamy Virus Vectors.

Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 5276-5276
Author(s):  
RuiJun Su ◽  
Rency L. Rosales ◽  
Martin Lochelt ◽  
Neil C. Josephson
Keyword(s):  
Stem Cells ◽  
Macaca Mulatta ◽  
High Titer ◽  
Foamy Virus ◽  
Embryonic Stem ◽  
Peptide Sequence ◽  
Leader Peptide ◽  
Serum Samples ◽  
Simian Foamy Virus ◽  
Prototype Foamy Virus

Abstract Because of their genetic and biological similarity to humans, non-human primates are the best pre-clinical models for testing the efficacy and safety of gene therapy systems. However, the presence of endogenous simian foamy virus infection in nearly all non-human primates kept in captivity complicates foamy virus (FV) vector stem cell transduction studies in these animals. A major concern is that repopulating cells exposed to FV vector stocks will elicit an immune response in non-human primate hosts. Though human serum does not inactivate prototype foamy virus (PFV) vectors, a one hour incubation of PFV vector stock in the presence of serum samples from Papio Cynophalus (baboon), Macaca Mulatta (rhesus macaque), or Macaca Fasicularis (long-tailed macaque) results in a 75–100% drop in titer. To overcome this serum mediated inactivation we sought to pseudotype PFV vectors in the feline foamy virus (FFV) envelope. The wild-type envelope from the FUV strain of FFV does not pseudotype our PFV vectors. Therefore we generated chimeras with regions of both the FFV and PFV envelope. By substituting portions of the FFV envelope leader peptide sequence and membrane spanning domain with corresponding PFV envelope regions we generated chimeric envelopes capable of high titer (105–106 FFU/ml) PFV vector production. Serum samples from Macaca Mulatta produced less inactivation of the FFV pseudotyped than the PFV pseudotyped vectors. Furthermore, both the PFV and FFV pseudotyped vectors demonstrated efficient transduction of baboon mesenchymal stem cells (27–43%) and baboon embryonic stem cells (37–40%). However, the FFV pseudotyped vectors transduced both human and baboon CD34+ cells less efficiently than the PFV pseudotyped vectors. We plan to test PFV vectors pseudotyped by other FV envelopes for inactivation by primate serum, and for their ability to transduce primate hematopoietic cells.

Simian Foamy Virus Prevalence in Macaca mulatta and Zookeepers

2012 ◽  
Vol 28 (6) ◽  
pp. 591-593 ◽  
Author(s):  
Fen Huang ◽  
Huixuan Wang ◽  
Shenrong Jing ◽  
Weikun Zeng
Keyword(s):  
Macaca Mulatta ◽  
Foamy Virus ◽  
Simian Foamy Virus ◽  
Virus Prevalence

scholarly journals Antigenic compartmentation of the primate and tree shrew cerebellum: a common topography of zebrin II in Macaca mulatta and Tupaia belangeri

2004 ◽  
Vol 204 (4) ◽  
pp. 257-269 ◽  
Author(s):  
Roy V. Sillitoe ◽  
Cordula R. Malz ◽  
Kathleen Rockland ◽  
Richard Hawkes
Keyword(s):  
Macaca Mulatta ◽  
Tree Shrew ◽  
Tupaia Belangeri ◽  
Zebrin Ii

The organization of frontoparietal cortex in the tree shrew (Tupaia belangeri): II. Connectional evidence for a frontal-posterior parietal network

2007 ◽  
Vol 501 (1) ◽  
pp. 121-149 ◽  
Author(s):  
Michael S. Remple ◽  
Jamie L. Reed ◽  
Iwona Stepniewska ◽  
David C. Lyon ◽  
Jon H. Kaas
Keyword(s):  
Tree Shrew ◽  
Tupaia Belangeri ◽  
Frontoparietal Cortex ◽  
Posterior Parietal

scholarly journals Contemporary Distribution, Estimated Age, and Prehistoric Migrations of Old World Monkey Retroviruses

Epidemiologia ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 46-67
Author(s):  
Antoinette C. van der Kuyl
Keyword(s):  
Close Contact ◽  
World Monkey ◽  
Foamy Virus ◽  
Endogenous Retrovirus ◽  
Papio Cynocephalus ◽  
Endogenous Virus ◽  
Simian Foamy Virus ◽  
Old World ◽  
T Lymphotropic Virus ◽  
Type D

Old World monkeys (OWM), simians inhabiting Africa and Asia, are currently affected by at least four infectious retroviruses, namely, simian foamy virus (SFV), simian immunodeficiency virus (SIV), simian T-lymphotropic virus (STLV), and simian type D retrovirus (SRV). OWM also show chromosomal evidence of having been infected in the past with four more retroviral species, baboon endogenous virus (BaEV), Papio cynocephalus endogenous virus (PcEV), simian endogenous retrovirus (SERV), and Rhesus endogenous retrovirus-K (RhERV-K/SERV-K1). For some of the viruses, transmission to other primates still occurs, resulting, for instance, in the HIV pandemic. Retroviruses are intimately connected with their host as they are normally spread by close contact. In this review, an attempt to reconstruct the distribution and history of OWM retroviruses will be made. A literature overview of the species infected by any of the eight retroviruses as well as an age estimation of the pathogens will be given. In addition, primate genomes from databases have been re-analyzed for the presence of endogenous retrovirus integrations. Results suggest that some of the oldest retroviruses, SERV and PcEV, have travelled with their hosts to Asia during the Miocene, when a higher global temperature allowed simian expansions. In contrast, younger viruses, such as SIV and SRV, probably due to the lack of a primate continuum between the continents in later times, have been restricted to Africa and Asia, respectively.

scholarly journals Simian Foamy Virus Transmission from Apes to Humans, Rural Cameroon

2007 ◽  
Vol 13 (9) ◽  
pp. 1314-1320 ◽  
Author(s):  
Sara Calattini ◽  
Edouard B.A. Betsem ◽  
Alain Froment ◽  
Philippe Mauclère ◽  
Patricia Tortevoye ◽  
...  
Keyword(s):  
Foamy Virus ◽  
Virus Transmission ◽  
Simian Foamy Virus ◽  
Rural Cameroon

MHC class I genes of the tree shrew Tupaia belangeri

2002 ◽  
Vol 53 (10-11) ◽  
pp. 984-988 ◽  
Author(s):  
Perris Flügge, Eberhard Fuchs, Ebe
Keyword(s):  
Mhc Class I ◽  
Tree Shrew ◽  
Class I ◽  
Tupaia Belangeri
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