Effect of Different Antiretroviral Drug Regimens on Body Fat Distribution of HIV-Infected South African Women

2013 ◽  
Vol 29 (3) ◽  
pp. 557-563 ◽  
Author(s):  
Julia H. Goedecke ◽  
Lisa K. Micklesfield ◽  
Naomi S. Levitt ◽  
Estelle V. Lambert ◽  
Sacha West ◽  
...  
Keyword(s):  
South African ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
African Women ◽  
Antiretroviral Drug ◽  
Drug Regimens ◽  
South African Women

BODY FAT DISTRIBUTION AND CARDIO-METABOLIC RISK FACTORS IN MIXED-ANCESTRY SOUTH AFRICAN WOMEN AND MEN

2018 ◽  
Vol 36 (Supplement 1) ◽  
pp. e145-e146
Author(s):  
A.P. Kengne ◽  
F.E. Davidson ◽  
T.E. Matsha ◽  
R.T. Erasmus ◽  
J.E. Goedecke
Keyword(s):  
Risk Factors ◽  
South African ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Metabolic Risk Factors ◽  
African Women ◽  
Metabolic Risk ◽  
Mixed Ancestry ◽  
South African Women

scholarly journals HDL Subclass Distribution Shifts with Increasing Central Adiposity

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Nicholas J. Woudberg ◽  
Sandrine Lecour ◽  
Julia H. Goedecke
Keyword(s):  
South African ◽  
Body Fat ◽  
Fat Mass ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
African Women ◽  
Black South African ◽  
Percentage Decrease ◽  
South African Women

Although cross-sectional studies have shown that obesity is associated with lower concentrations of large high-density lipoprotein (HDL) subclasses, it is unknown if changes in HDL subclasses are related to changes in body fat and its distribution over time. We therefore assessed changes in HDL subclass distribution over a 5.5-year free-living follow-up period in 24 black South African women. At baseline and follow-up, body composition and body fat distribution were measured using anthropometry, dual X-ray absorptiometry, and computerized tomography. HDL subclass distribution was quantified using Lipoprint®. Over the 5.5-year follow-up period, body fat (+17.3 ± 4.5 kg,p<0.05) and trunk fat mass (+7.4 ± 1.9%, % fat mass, FM,p<0.05) increased, while leg fat mass (−2.53 ± 0.56%, % FM,p<0.001) and the distribution of large (−6.43 ± 2.12%,p<0.05) HDL subclasses decreased. A percentage decrease in large HDL subclasses was associated with a percentage increase in central fat mass (visceral adipose tissue (VAT) area,p<0.05) and a percentage decrease in peripheral fat mass (leg fat mass). These preliminary findings suggest that a relative redistribution of body fat from the periphery to the abdominal region were associated with a decrease HDL subclass size in black South African women and provide a novel link between body fat distribution and lipidology in this population.

ISH NIA PS 03-08 THE ROLE OF BODY FAT AND FAT DISTRIBUTION IN HYPERTENSION RISK IN URBAN BLACK SOUTH AFRICAN WOMEN

2016 ◽  
Vol 34 (Supplement 1) ◽  
pp. e283
Author(s):  
Cindy George ◽  
Julia Goedecke ◽  
Nigel Crowther ◽  
Nicole Jaff ◽  
Andre Kengne ◽  
...  
Keyword(s):  
South African ◽  
Body Fat ◽  
Fat Distribution ◽  
African Women ◽  
Black South African ◽  
Hypertension Risk ◽  
South African Women

scholarly journals The Role of Body Fat and Fat Distribution in Hypertension Risk in Urban Black South African Women

PLoS ONE ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. e0154894 ◽  
Author(s):  
Cindy George ◽  
Julia H. Goedecke ◽  
Nigel J. Crowther ◽  
Nicole G. Jaff ◽  
Andre P. Kengne ◽  
...  
Keyword(s):  
South African ◽  
Body Fat ◽  
Fat Distribution ◽  
African Women ◽  
Black South African ◽  
Hypertension Risk ◽  
South African Women

[PP.03.08] THE ROLE OF BODY FAT AND FAT DISTRIBUTION IN HYPERTENSION RISK IN URBAN BLACK SOUTH AFRICAN WOMEN

2016 ◽  
Vol 34 ◽  
pp. e128
Author(s):  
C. George ◽  
J.H. Goedecke ◽  
N.J. Crowther ◽  
N.G. Jaff ◽  
A.P. Kengne ◽  
...  
Keyword(s):  
South African ◽  
Body Fat ◽  
Fat Distribution ◽  
African Women ◽  
Black South African ◽  
Hypertension Risk ◽  
South African Women

Degree of obesity influences the relationship of PAI-1 with body fat distribution and metabolic variables in African women

2016 ◽  
Vol 146 ◽  
pp. 95-102 ◽  
Author(s):  
Sunelle A. Barnard ◽  
Marlien Pieters ◽  
Cornelie Nienaber-Rousseau ◽  
Herculina S. Kruger
Keyword(s):  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
African Women ◽  
Metabolic Variables ◽  
Relationship Of ◽  
The Relationship ◽  
Pai 1

scholarly journals Circulating and Adipose Tissue Fatty Acid Composition in Black South African Women with Obesity: A Cross-Sectional Study

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1619
Author(s):  
Pamela A. Nono Nankam ◽  
Paul J. van Jaarsveld ◽  
Elin Chorell ◽  
Melony C. Fortuin-de Smidt ◽  
Kevin Adams ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Fatty Acid ◽  
South African ◽  
Body Fat ◽  
Unsaturated Fatty Acids ◽  
African Women ◽  
Black South African ◽  
Fa Composition ◽  
South African Women

Background and Aims: During positive energy balance, excess lipid storage in subcutaneous adipose tissue (SAT) is associated with increased lipolysis. Elevated circulating fatty acid (FA) concentrations from both SAT lipolysis and dietary fat intake may result in visceral adipose tissue (VAT) accumulation, impairment of glucose metabolism, altogether increasing obesity-associated metabolic risks. We aimed to test the hypothesis that FA composition of red blood cell total phospholipids (RBC-TPL) and SAT is associated with body fat centralisation (VAT/SAT ratio) and insulin sensitivity (SI) in black South African women with obesity. Methods: Participants’ (n = 41) body fat composition and distribution, SI, and RBC-TPL, abdominal and gluteal SAT (gSAT) FA composition (gas-liquid chromatography) were measured. Results: RBC-TPL contained higher proportions of saturated fatty acids (SFAs) than SAT (p < 0.001), which were associated with lower SI (p < 0.05). Mono-unsaturated fatty acids (MUFAs) and stearoyl-CoA desaturase-1 (SCD1)-16 were lower, while poly-unsaturated fatty acids (PUFAs), and delta-5 and delta-6 desaturase indices were higher in RBC-TPL than SAT (p < 0.001). Interestingly, FA profiles differed between SAT depots with higher SFAs and lower MUFAs, SCD1-16 and SCD1-18 indices in abdominal compared to gluteal SAT (p < 0.01). In both SAT depots, higher SFAs and lower PUFAs (n-3 and n-6) correlated with lower VAT/SAT ratio; and lower PUFAs (n-3 and n-6) and higher total MUFA correlated with higher SI. Conclusion: Our findings confirm the relationships between the FA composition of RBC-TPL and SAT and metabolic risk in black women with obesity, which are dependent on both the FA class, and the tissue type/blood compartment in which they are distributed.

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