Short Communication: Effects of Age on Virologic Suppression and CD4 Cell Response in HIV-Positive Patients Initiating Combination Antiretroviral Therapy

2012 ◽  
Vol 28 (12) ◽  
pp. 1579-1583 ◽  
Author(s):  
Leah Szadkowski ◽  
Alice Tseng ◽  
Sharon L. Walmsley ◽  
Irving Salit ◽  
Janet M. Raboud
Keyword(s):  
Antiretroviral Therapy ◽  
Cell Response ◽  
Short Communication ◽  
Hiv Positive ◽  
Virologic Suppression ◽  
Combination Antiretroviral Therapy ◽  
Communication Effects ◽  
Cd4 Cell

scholarly journals Do Sex and Race/Ethnicity Influence CD4 Cell Response in Patients Who Achieve Virologic Suppression during Antiretroviral Therapy?

2003 ◽  
Vol 37 (3) ◽  
pp. 433-437 ◽  
Author(s):  
T. P. Giordano ◽  
J. A. Wright ◽  
M. Q. Hasan ◽  
A. C. White ◽  
E. A. Graviss ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Cell Response ◽  
Virologic Suppression ◽  
Race Ethnicity ◽  
Cd4 Cell

Failure to achieve a CD4+ cell count response on combination antiretroviral therapy despite consistent viral load suppression

AIDS ◽  
2014 ◽  
Vol 28 (6) ◽  
pp. 919-924 ◽  
Author(s):  
Jemma L. O’Connor ◽  
Colette J. Smith ◽  
Fiona C. Lampe ◽  
Teresa Hill ◽  
Mark Gompels ◽  
...  
Keyword(s):  
Viral Load ◽  
Antiretroviral Therapy ◽  
Cell Count ◽  
Combination Antiretroviral Therapy ◽  
Viral Load Suppression ◽  
Cd4 Cell Count ◽  
Count Response ◽  
Cd4 Cell

scholarly journals Recent Immigrants Show improved Clinical Outcomes at a Tertiary Care HIV Clinic

2012 ◽  
Vol 23 (1) ◽  
pp. 9-14 ◽  
Author(s):  
Janet Raboud ◽  
Sandra Blitz ◽  
Tony Antoniou ◽  
Mona Loutfy ◽  
Sharon Walmsley
Keyword(s):  
Antiretroviral Therapy ◽  
Proportional Hazards ◽  
Tertiary Care ◽  
Clinic Visit ◽  
Virologic Suppression ◽  
Combination Antiretroviral Therapy ◽  
Recent Immigrants ◽  
Time To Death ◽  
Hiv Test ◽  
Female Immigrants

BACKGROUND: In recent years, the proportion of patients attending tertiary care HIV clinics who are recent immigrants to Canada has increased dramatically.METHODS: Among patients first seen at the Toronto Hospital Immunodeficiency Clinic (Toronto, Ontario) between January 1, 2000 and August 31, 2009, the time to death from the first positive HIV test was compared between individuals who had immigrated to Canada within 10 years of their first visit and individuals who were either Canadian-born or who had immigrated more than 10 years before their first clinic visit. In addition, for the antiretroviral-naive patients in these two groups who initiated combination antiretroviral therapy, the time to and the duration of virologic suppression were compared.RESULTS: In a multivariable proportional hazards (PH) model, recent immigrant status was associated with decreased mortality (HR 0.11, P=0.03) after adjusting for age, CD4 count and the risk factor for men having sex with men. In multivariable PH models, recent female immigrants achieved virologic suppression more quickly (HR 1.51, P=0.02), while male immigrants (HR 1.14, P=0.44) and female nonimmigrants (HR 0.90, P=0.61) had similar times to virologic suppression as male nonimmigrants, respectively, after adjusting for the year of and viral load at combination antiretroviral therapy initiation. When pregnant women were removed from the analysis, there were no significant differences in the rates of virologic rebound according to sex or immigration status.DISCUSSION: Despite the perceived barriers of newcomers to Canada, mortality was lower among recent immigrants and virologic suppression was achieved more quickly in recent female immigrants.

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