Moderate Prevalence of Transmitted Drug Resistance and Interiorization of HIV Type 1 Subtype C in the Inland North State of Tocantins, Brazil

2011 ◽  
Vol 27 (10) ◽  
pp. 1081-1087 ◽  
Author(s):  
Bruna Coelho Carvalho ◽  
Ludimila Paula Vaz Cardoso ◽  
Sirlene Damasceno ◽  
Mariane Martins de Araújo Stefani
Keyword(s):  
Drug Resistance ◽  
Transmitted Drug Resistance ◽  
Subtype C ◽  
Hiv Type 1

Molecular Phylogenetics of Transmitted Drug Resistance in Newly Diagnosed HIV Type 1 Individuals in Denmark, a Nation-Wide Study

2011 ◽  
Vol 27 (12) ◽  
pp. 1283-1290 ◽  
Author(s):  
Anne Margrethe Audelin ◽  
Jan Gerstoft ◽  
Niels Obel ◽  
Lars Mathiesen ◽  
Alex Laursen ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Molecular Phylogenetics ◽  
Transmitted Drug Resistance ◽  
Newly Diagnosed ◽  
Hiv Type 1

Drug Resistance in Plasma and Breast Milk after Single-Dose Nevirapine in Subtype C HIV Type 1: Population and Clonal Sequence Analysis

2007 ◽  
Vol 23 (8) ◽  
pp. 1055-1061 ◽  
Author(s):  
Seble Kassaye ◽  
Esther Lee ◽  
Rami Kantor ◽  
Elizabeth Johnston ◽  
Mark Winters ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Single Dose ◽  
Sequence Analysis ◽  
Breast Milk ◽  
Subtype C ◽  
Single Dose Nevirapine ◽  
Hiv Type 1 ◽  
Clonal Sequence

Sustained Profile of Transmitted Drug Resistance Mutations for More Than 10 Years in an HIV Type 1-Infected Patient

2011 ◽  
Vol 27 (1) ◽  
pp. 41-45 ◽  
Author(s):  
Lorena Martínez-Prats ◽  
Joanna Luczkowiak ◽  
Francisca Gutiérrez ◽  
Sagrario Zurita ◽  
Silvana Fiorante ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Infected Patient ◽  
Transmitted Drug Resistance ◽  
Resistance Mutations ◽  
Drug Resistance Mutations ◽  
Hiv Type 1

scholarly journals HIV Type 1 Subtype C Drug Resistance among Pediatric and Adult South African Patients Failing Antiretroviral Therapy

2008 ◽  
Vol 24 (11) ◽  
pp. 1449-1454 ◽  
Author(s):  
Visva Pillay ◽  
Candice Pillay ◽  
Rami Kantor ◽  
Francois Venter ◽  
Leon Levin ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
South African ◽  
Subtype C ◽  
Hiv Type 1 ◽  
African Patients

scholarly journals Short Communication: Transmitted Drug Resistance and Molecular Epidemiology in Antiretroviral Naive HIV Type 1-Infected Patients in Rhode Island

2011 ◽  
Vol 27 (3) ◽  
pp. 275-281 ◽  
Author(s):  
Philip A. Chan ◽  
Karen Tashima ◽  
Charles P. Cartwright ◽  
Fizza S. Gillani ◽  
Orli Mintz ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Molecular Epidemiology ◽  
Rhode Island ◽  
Short Communication ◽  
Transmitted Drug Resistance ◽  
Hiv Type 1

scholarly journals Drug Resistance Mutations in Drug-Naive HIV Type 1 Subtype C-Infected Individuals from Rural Malawi

2011 ◽  
Vol 27 (4) ◽  
pp. 439-444 ◽  
Author(s):  
Vijay Bansode ◽  
Zuzanna J. Drebert ◽  
Simon A.A. Travers ◽  
Emmanuel Banda ◽  
Anna Molesworth ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Resistance Mutations ◽  
Subtype C ◽  
Drug Resistance Mutations ◽  
Drug Naïve ◽  
Hiv Type 1

scholarly journals Prevalence of HIV Drug Resistance Mutations in HIV Type 1 Isolates in Antiretroviral Therapy Naïve Population from Northern India

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
S. Sinha ◽  
H. Ahmad ◽  
R. C. Shekhar ◽  
N. Kumar ◽  
L. Dar ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
Resistance Mutations ◽  
Subtype C ◽  
Hiv Drug Resistance ◽  
Northern India ◽  
Subtype B ◽  
Hiv Type 1 ◽  
Hiv 1

Objective. The increased use of antiretroviral therapy (ART) has reduced the morbidity and mortality associated with HIV, adversely leading to the emergence of HIV drug resistance (HIVDR). In this study we aim to evaluate the prevalence of HIVDR mutations in ART-naive HIV-1 infected patients from northern India.Design. Analysis was performed using Viroseq genotyping system based on sequencing of entire protease and two-thirds of the Reverse Transcriptase (RT) region ofpolgene.Results. Seventy three chronic HIV-1 infected ART naïve patients eligible for first line ART were enrolled from April 2006 to August 2008. In 68 patients DNA was successfully amplified and sequencing was done. 97% of HIV-1 strains belonged to subtype C, and one each to subtype A1 and subtype B. The overall prevalence of primary DRMs was 2.9% [2/68, 95% confidence interval (CI), 0.3%–10.2%]. One patient had a major RT mutation M184V, known to confer resistance to lamivudine, and another had a major protease inhibitor (PI) mutation D30N that imparts resistance to nelfinavir.Conclusion. Our study shows that primary HIVDR mutations have a prevalence of 2.9% among ART-naive chronic HIV-1 infected individuals.

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