Documenting Intermenstrual Bleeding in a Vaginal Microbicide Study: Case Reports and Lessons Learned

2006 ◽  
Vol 22 (3) ◽  
pp. 294-296 ◽  
Author(s):  
Smita Joshi ◽  
Soma Dutta ◽  
Beverly Bell ◽  
Albert Profy ◽  
JoAnn Kuruc ◽  
...  
Keyword(s):  
Case Reports ◽  
Lessons Learned ◽  
Vaginal Microbicide ◽  
Study Case

scholarly journals (A292) Disaster Assessment and Gathering Medical Intelligence Following a Major Public Health or Complex Humanitarian Emergency

2011 ◽  
Vol 26 (S1) ◽  
pp. s81-s81 ◽  
Author(s):  
M. Reilly
Keyword(s):  
Public Health ◽  
Hurricane Katrina ◽  
Case Reports ◽  
Chain Condition ◽  
Lessons Learned ◽  
Limited Information ◽  
Humanitarian Emergency ◽  
Rescue Workers ◽  
Disaster Assessment ◽  
Agricultural Trends

IntroductionImmediately following a major public health emergency or complex humanitarian emergency such as the South East Asian Tsunami in 2004, the Haitian Earthquake in 2010 or Hurricane Katrina in 2005, there is a critical need to rapidly and as accurately as possible gather information not limited to morbidity and mortality, but necessary to assess the stability and existence of a public health or medical infrastructure, logistic supply chain, condition of food, water and shelter for victims and rescue workers, and particularly the security and stability of the region following the incident. With this information, only then can an effective humanitarian response be planned and executed that meets the actual versus perceived needs of an affected population.MethodsSpecific disaster risk assessment and medical intelligence techniques will be presented that are currently used by a variety of relief organizations. Specific topics of discussion include: Disaster epidemiology; Indicators of health in populations; Systems of surveillance; Impact of weather and climate; Displaced populations and refugee health; Tactical and combat medical intelligence; Zoonotic diseases; Agricultural trends and food security; Public health and health system infrastructure assessment; and Personal and physical security concerns.ConclusionsUtilizing case reports, best-practices and lessons learned from numerous international humanitarian responses, this session will guide participants though the performance of a rapid disaster assessment and the gathering of critical medical intelligence to determine the kinds and types of resources needed in an affected area. And the process of utilizing limited information to plan humanitarian relief efforts.

scholarly journals Case Reports: Multifaceted Experiences Treating Youth with Severe Obesity

2019 ◽  
Vol 16 (6) ◽  
pp. 927 ◽  
Author(s):  
Karen Schaller ◽  
Linda Stephenson-Somers ◽  
Adolfo Ariza ◽  
Maheen Quadri ◽  
Helen Binns
Keyword(s):  
Severe Obesity ◽  
Child Protective Services ◽  
Case Reports ◽  
Tertiary Care ◽  
Lessons Learned ◽  
Medical Team ◽  
Health Providers ◽  
Protective Services ◽  
Integral Role

The management of youth with severe obesity is strongly impacted by social determinants of health and family dynamics. We present case studies of three patients seen in our tertiary care obesity treatment clinic as examples of the challenges faced by these patients and their families, as well as by the medical team. We discuss how these cases illustrate potential barriers to care, the role of child protective services, and we reflect upon lessons learned through the care of these patients. These cases highlight the need for comprehensive care in the management of youth with severe obesity, which can include: visits to multiple medical specialists, and mental and behavioral health providers; school accommodations; linkage to community resources; and, potentially, child protective services involvement. Through the care of these youth, our medical team gained more experience with using anti-obesity medications and meal replacements. The care of these youth also heightened our appreciation for the integral role of mental health services and community-based resources in the management of youth with severe obesity.

scholarly journals Remdesivir for Early COVID-19 Treatment of High-Risk Individuals Prior to or at Early Disease Onset—Lessons Learned

Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 963
Author(s):  
Lars Dölken ◽  
August Stich ◽  
Christoph D. Spinner
Keyword(s):  
Clinical Trials ◽  
Clinical Efficacy ◽  
Case Reports ◽  
Antiviral Treatment ◽  
Treatment Options ◽  
Disease Onset ◽  
Antiviral Agent ◽  
Individual Case ◽  
Lessons Learned ◽  
Disease Stage

After more than one year of the COVID-19 pandemic, antiviral treatment options against SARS-CoV-2 are still severely limited. High hopes that had initially been placed on antiviral drugs like remdesivir have so far not been fulfilled. While individual case reports provide striking evidence for the clinical efficacy of remdesivir in the right clinical settings, major trials failed to demonstrate this. Here, we highlight and discuss the key findings of these studies and underlying reasons for their failure. We elaborate on how such shortcomings should be prevented in future clinical trials and pandemics. We suggest in conclusion that any novel antiviral agent that enters human trials should first be tested in a post-exposure setting to provide rapid and solid evidence for its clinical efficacy before initiating further time-consuming and costly clinical trials for more advanced disease. In the COVID-19 pandemic this might have established remdesivir early on as an efficient antiviral agent at a more suitable disease stage which would have saved many lives, in particular in large outbreaks within residential care homes.

Fetus in Fetu: Lessons Learned from a Large Multicenter Cohort Study

2019 ◽  
Vol 30 (04) ◽  
pp. 343-349
Author(s):  
Heba M. A. Taher ◽  
Mostafa Abdellatif ◽  
Ahmed Mohamed Kadry Wishahy ◽  
Saber Waheeb ◽  
Yasser Saadeldin ◽  
...  
Keyword(s):  
Pediatric Surgery ◽  
Single Case ◽  
Case Reports ◽  
Lessons Learned ◽  
Pathology Report ◽  
Multicenter Cohort Study ◽  
Complete Excision ◽  
Diagnostic Modality ◽  
Fetus In Fetu ◽  
Increased Risk

Abstract Introduction Fetus in fetu (FIF) is an extremely rare condition of abnormal twinning during embryogenesis. Most publications are single case reports. We describe the combined experience of four large tertiary referral centers with FIF which were not previously reported or published, and thereby draw conclusions to establish criteria for the workup, diagnosis, and management including intraoperative risk. Materials and Methods A survey was forwarded to a national pediatric surgery group which includes members from all pediatric surgery centers in the country enquiring about unpublished cases of FIF encountered over a 20-year interval. The cohort was analyzed for age of presentation, type of presentation, diagnostic workup, surgical management, and outcome. Results From 1998 to 2018, a total of 10 FIF cases were included in the study. Mean age of presentation was 4 months. Computed tomography and ultrasound were the main preoperative diagnostic modality in our cohort. Resection of the mass was curative in nine cases. Two cases in which the FIF was in direct topographic proximity to the biliary tree suffered severe intraoperative or lethal postoperative complications. Conclusion Complete excision of FIF is the treatment of choice and generally results in excellent long-term quality of life. Mortality is rare and may be associated with biliary involvement and retroperitoneal right upper quadrant location of the FIF tends to be associated with increased risk in excision, and there is also a possible association with the presence of immature elements in the pathology report.

scholarly journals Establishing Cancer Treatment Programs in Resource-Limited Settings: Lessons Learned From Guatemala, Rwanda, and Vietnam

2018 ◽  
pp. 1-14
Author(s):  
Claire M. Wagner ◽  
Federico Antillón ◽  
François Uwinkindi ◽  
Tran Van Thuan ◽  
Sandra Luna-Fineman ◽  
...  
Keyword(s):  
Clinical Education ◽  
Cancer Care ◽  
Care Delivery ◽  
Case Reports ◽  
Lessons Learned ◽  
Treatment Programs ◽  
Program Leaders ◽  
Policy Goals ◽  
Resource Limited ◽  
Health Care Delivery Systems

Purpose The global burden of cancer is slated to reach 21.4 million new cases in 2030 alone, and the majority of those cases occur in under-resourced settings. Formidable changes to health care delivery systems must occur to meet this demand. Although significant policy advances have been made and documented at the international level, less is known about the efforts to create national systems to combat cancer in such settings. Methods With case reports and data from authors who are clinicians and policymakers in three financially constrained countries in different regions of the world—Guatemala, Rwanda, and Vietnam, we examined cancer care programs to identify principles that lead to robust care delivery platforms as well as challenges faced in each setting. Results The findings demonstrate that successful programs derive from equitably constructed and durable interventions focused on advancement of local clinical capacity and the prioritization of geographic and financial accessibility. In addition, a committed local response to the increasing cancer burden facilitates engagement of partners who become vital catalysts for launching treatment cascades. Also, clinical education in each setting was buttressed by international expertise, which aided both professional development and retention of staff. Conclusion All three countries demonstrate that excellent cancer care can and should be provided to all, including those who are impoverished or marginalized, without acceptance of a double standard. In this article, we call on governments and program leaders to report on successes and challenges in their own settings to allow for informed progression toward the 2025 global policy goals.

scholarly journals Aortoenteric fistula after endovascular mycotic aortic aneurysm exclusion: lessons learned during the COVID-19 era

2021 ◽  
Vol 14 (2) ◽  
pp. e238875
Author(s):  
Ahmed Hassan ◽  
Aazeb Khan ◽  
Bella Huasen ◽  
Mohamed Banihani
Keyword(s):  
Aortic Aneurysm ◽  
Case Reports ◽  
Postoperative Recovery ◽  
Lessons Learned ◽  
Aortoenteric Fistula ◽  
Surgical Removal ◽  
Ct Angiogram ◽  
Aneurysm Repair ◽  
Aortic Aneurysm Repair

We report a case of aortoenteric fistula 2 years following endovascular aortic aneurysm repair (EVAR) for mycotic aneurysm presenting as upper gastrointestinal bleeding. Initial CT angiogram did not reveal the bleeding or connection to bowel, but endoscopy was suspicious of endograft in the duodenum. Management required a multidisciplinary approach. To stabilise the patient and to control bleeding, a ‘bridging’ endograft extension was performed. This was followed by open surgical removal of the EVAR endograft and lower limb in situ revascularisation. During postoperative recovery, the patient developed atypical, staged multisystemic symptoms (cardiac, pulmonary and neurological). With increasing awareness of the COVID-19 pandemic, the patient was found SARS-CoV-2-positive, which explained the progression of his symptoms. This was also reflected on other case reports in literature later.

scholarly journals Applying Engagement Frameworks to Case Scenarios: A Retrospective Analysis

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 789-789
Author(s):  
Erin McGaffigan
Keyword(s):  
Interest Group ◽  
Research Study ◽  
Lessons Learned ◽  
Future Research ◽  
User Engagement ◽  
Ethical Considerations ◽  
Patient Centered ◽  
Factors Influencing ◽  
Creative Solutions ◽  
Study Case

Abstract The LeadingAge LTSS Center @UMass Boston has worked with the Patient-Centered Outcomes Research Institute (PCORI), service recipients, researchers, and providers since 2017 to understand the obstacles and creative solutions for meaningful and effective engagement in research. The LTSS Center’s work has been informed by multiple engagement frameworks, including Dr. McGaffigan’s 2011 PAE Attention Framework, the result of a multi-state, multi-site research study examining the factors to user engagement in Cash & Counseling programs. In this presentation, we will apply the PAE Attention Framework (2011), the PCORI Engagement Rubric (2014), and the NHS INVOLVE Framework (2015) to three research study case scenarios to understand the strategies used, outcomes realized, and factors influencing engagement success. Lessons learned from each and their application to future research will be discussed, including ethical considerations. Part of a symposium sponsored by the Patient/Person Engagement in Research Interest Group.

scholarly journals «Heredes de Plauto stampadore deno avere infrascritte robe e dinari»

2020 ◽  
Author(s):  
Elena Gatti
Keyword(s):  
Case Reports ◽  
Cost Of Living ◽  
15Th Century ◽  
Study Case ◽  
The Cost ◽  
Book Prices

Two archival sources of the late 15th century allow to outline some considerations and comparisons between the cost of living and book prices in Bologna. The first reports books stored in Bologna by the printer/bookseller Francesco Platone de’ Benedetti during his lifetime; the second, the most important for this study-case, reports the prices and sales of those books made by his heirs.

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