Synergistic Neutralization of a Chimeric SIV/HIV Type 1 Virus with Combinations of Human Anti-HIV Type 1 Envelope Monoclonal Antibodies or Hyperimmune Globulins

1997 ◽  
Vol 13 (8) ◽  
pp. 647-656 ◽  
Author(s):  
AN LI ◽  
TIMOTHY W. BABA ◽  
JOSEPH SODROSKI ◽  
SUSAN ZOLLA-PAZNER ◽  
MIROSLAW K. GORNY ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Hiv Type 1 ◽  
Anti Hiv

scholarly journals Seroprevalence of Hepatitis C, Hepatitis B, Cytomegalovirus, and Human Immunodeficiency Viruses in Multitransfused Thalassemic Children in Upper Egypt

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Ramadan A. Mahmoud ◽  
Abdel-Azeem M. El-Mazary ◽  
Ashraf Khodeary
Keyword(s):  
Hepatitis C ◽  
Blood Transfusion ◽  
Hepatitis B ◽  
Thalassemia Major ◽  
Upper Egypt ◽  
Egyptian Children ◽  
Hiv Type 1 ◽  
Anti Hiv

Background. Frequent blood transfusions in thalassemia major children expose them to the risk of transfusion-transmitted infections (TTIs). The aim of this study was to estimate the prevalence of hepatitis C virus (HCV), hepatitis B virus (HBV), human immunodeficiency virus (HIV), and cytomegalovirus (CMV) in thalassemic children attending the Pediatrics Departments of both Sohag and Minia Universities of Upper Egypt, during the period from May 2014 to May 2015.Methods. Serum samples were screened for hepatitis B surface antigen (HBsAg), anti-HCV, anti-CMV, and anti-HIV type 1 and type 2 using the Vitek Immunodiagnostic Assay System.Results. The frequencies of anti-HCV, HBsAg, anti-CMV, and anti-HIV type 1 and type 2 were found to be 37.11%, 4.12%, 4.12%, 0.00%, and 0.00%, respectively. Seropositivity for anti-HCV, HBsAg, and anti-CMV increased with increasing age of the patients, duration of the disease, serum ferritin level (ng/mL), and liver enzymes (U/L), while it was not significantly associated with gender, frequency of blood transfusion, or the status of splenectomy operation (P>0.05).Conclusion. The frequency of TTIs, especially HCV, is considerably high among Egyptian children with thalassemia major. It is therefore important to implement measures to improve blood transfusion screening, such as polymerase chain reaction, in order to reduce TTIs from blood donor units.

The Design, Production, and Validation of an Anti-HIV Type 1 Ribozyme

2003 ◽  
pp. 51-64
Author(s):  
Lun-Quan Sun ◽  
Wayne Gerlach ◽  
Geoff Symonds
Keyword(s):  
Design Production ◽  
Hiv Type 1 ◽  
Anti Hiv

Molecular Characterization of Variable Heavy and Light Chain Regions of Five HIV Type 1-Specific Human Monoclonal Antibodies*

1994 ◽  
Vol 10 (12) ◽  
pp. 1639-1649 ◽  
Author(s):  
ERIC M.M. van der DONK ◽  
MARTIN SCHUTTEN ◽  
ALBERT D.M.E. OSTERHAUS ◽  
ROGER W.J. van der HEIJDEN
Keyword(s):  
Monoclonal Antibodies ◽  
Molecular Characterization ◽  
Light Chain ◽  
Human Monoclonal Antibodies ◽  
Variable Heavy ◽  
Hiv Type 1

Chloroquine Exerts an Additive in Vitro Anti-HIV Type 1 Effect When Associated with Didanosine and Hydroxyurea

1999 ◽  
Vol 15 (14) ◽  
pp. 1241-1247 ◽  
Author(s):  
Johan R. Boelaert ◽  
Kirk Sperber ◽  
Jacques Piette
Keyword(s):  
Hiv Type 1 ◽  
Anti Hiv

A Potent Anti-HIV Immunotoxin Blocks Spreading Infection by Primary HIV Type 1 Isolates in Multiple Cell Types

2004 ◽  
Vol 20 (2) ◽  
pp. 145-150 ◽  
Author(s):  
Kira K. Lueders ◽  
Stephen C. De Rosa ◽  
Antonio Valentin ◽  
George N. Pavlakis ◽  
Mario Roederer ◽  
...  
Keyword(s):  
Cell Types ◽  
Multiple Cell ◽  
Hiv Type 1 ◽  
Anti Hiv

Anti-HIV Type 1 Activity of 3′-Fluoro-3′-Deoxythymidine for Several Different Multidrug-Resistant Mutants

2001 ◽  
Vol 17 (5) ◽  
pp. 401-407 ◽  
Author(s):  
Eun-Young Kim ◽  
Lotta Vrang ◽  
Bo Öberg ◽  
Thomas C. Merigan
Keyword(s):  
Multidrug Resistant ◽  
Hiv Type 1 ◽  
Resistant Mutants ◽  
Anti Hiv
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