Effects of Scalp Acupuncture Versus Upper and Lower Limb Acupuncture on Signal Activation of Blood Oxygen Level Dependent (BOLD) fMRI of the Brain and Somatosensory Cortex

2009 ◽  
Vol 15 (11) ◽  
pp. 1193-1200 ◽  
Author(s):  
Seong-Uk Park ◽  
Ae-Sook Shin ◽  
Geon-Ho Jahng ◽  
Sang-Kwan Moon ◽  
Jung-Mi Park
Keyword(s):  
Somatosensory Cortex ◽  
Lower Limb ◽  
Blood Oxygen Level Dependent ◽  
Scalp Acupuncture ◽  
Blood Oxygen ◽  
Oxygen Level ◽  
Blood Oxygen Level ◽  
Bold Fmri ◽  
The Brain ◽  
Signal Activation

Low-frequency blood oxygen level-dependent fluctuations in the brain white matter: more than just noise

2017 ◽  
Vol 62 (9) ◽  
pp. 656-657 ◽  
Author(s):  
Gong-Jun Ji ◽  
Wei Liao ◽  
Fang-Fang Chen ◽  
Lei Zhang ◽  
Kai Wang
Keyword(s):  
White Matter ◽  
Low Frequency ◽  
Blood Oxygen Level Dependent ◽  
Blood Oxygen ◽  
Oxygen Level ◽  
Blood Oxygen Level ◽  
Brain White Matter ◽  
The Brain

Differential Localization of Pain-Related Neural Responses During Acupuncture Stimulation Using Blood Oxygen Level Dependent (BOLD) fMRI in a Canine Model

2012 ◽  
Vol 40 (05) ◽  
pp. 919-936 ◽  
Author(s):  
Suk-Ki Chang ◽  
Geon-Ho Jahng ◽  
Sung-Ho Lee ◽  
Il-Whan Choi ◽  
Chi-Bong Choi ◽  
...  
Keyword(s):  
Local Anesthesia ◽  
Canine Model ◽  
Blood Oxygen Level Dependent ◽  
Brain Regions ◽  
Blood Oxygen ◽  
Oxygen Level ◽  
Blood Oxygen Level ◽  
Bold Fmri ◽  
Acupuncture Stimulation ◽  
Reticular Activating System

The objective of this study was to differentiate the neuronal responses, which was related or unrelated, to pain associated with acupuncture stimulation, and to localize the brain regions with response to stimulation that is unrelated to pain by using Blood Oxygen Level Dependent (BOLD) functional MRI (fMRI). BOLD fMRI was performed in six normal healthy beagle dogs, during placebo and verum acupuncture stimulations, at the right side of BL60 (KunLun) acupoint before and after local anesthesia of the acupoint. The order of the four sessions was placebo; verum acupuncture stimulation; before local anesthesia; and followed by the same stimulation after local anesthesia. One-sample t-test analysis was performed to localize the activated or deactivated areas, during both pre-anesthesia and post-anesthesia. In order to compare the pre-anesthesia to post-anesthetic responses, and placebo to verum acupuncture stimulation, within-subject analysis was performed. The post-anesthetic verum acupuncture stimulation resulted in increased activations in the left somatic afferent area I and II, right visual and auditory association area, and the descending reticular activating system of the brainstem. In addition, differential areas during post-anesthesia compared to that of the pre-anesthesia were in the left olfactory peduncle and descending reticular activating system of the brainstem. These results indicate that the areas of specific neural pathway are considered to be unrelated to the pain response during acupuncture stimulation.

scholarly journals Systematic Review: Anesthetic Protocols and Management as Confounders in Rodent Blood Oxygen Level Dependent Functional Magnetic Resonance Imaging (BOLD fMRI)—Part B: Effects of Anesthetic Agents, Doses and Timing

Animals ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 199
Author(s):  
Aline R. Steiner ◽  
Frédérik Rousseau-Blass ◽  
Aileen Schroeter ◽  
Sonja Hartnack ◽  
Regula Bettschart-Wolfensberger
Keyword(s):  
Magnetic Resonance Imaging ◽  
Systematic Review ◽  
Magnetic Resonance ◽  
Blood Oxygen Level Dependent ◽  
Blood Oxygen ◽  
Oxygen Level ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Blood Oxygen Level ◽  
Bold Fmri

In rodent models the use of functional magnetic resonance imaging (fMRI) under anesthesia is common. The anesthetic protocol might influence fMRI readouts either directly or via changes in physiological parameters. As long as those factors cannot be objectively quantified, the scientific validity of fMRI in rodents is impaired. In the present systematic review, literature analyzing in rats and mice the influence of anesthesia regimes and concurrent physiological functions on blood oxygen level dependent (BOLD) fMRI results was investigated. Studies from four databases that were searched were selected following pre-defined criteria. Two separate articles publish the results; the herewith presented article includes the analyses of 83 studies. Most studies found differences in BOLD fMRI readouts with different anesthesia drugs and dose rates, time points of imaging or when awake status was compared to anesthetized animals. To obtain scientifically valid, reproducible results from rodent fMRI studies, stable levels of anesthesia with agents suitable for the model under investigation as well as known and objectively quantifiable effects on readouts are, thus, mandatory. Further studies should establish dose ranges for standardized anesthetic protocols and determine time windows for imaging during which influence of anesthesia on readout is objectively quantifiable.

Blood oxygen-level dependent functional assessment of cerebrovascular reactivity: Feasibility for intraoperative 3 Tesla MRI

2016 ◽  
Vol 77 (2) ◽  
pp. 806-813 ◽  
Author(s):  
Jorn Fierstra ◽  
Jan-Karl Burkhardt ◽  
Christiaan Hendrik Bas van Niftrik ◽  
Marco Piccirelli ◽  
Athina Pangalu ◽  
...  
Keyword(s):  
Functional Assessment ◽  
Blood Oxygen Level Dependent ◽  
Cerebrovascular Reactivity ◽  
3 Tesla ◽  
Blood Oxygen ◽  
Oxygen Level ◽  
Blood Oxygen Level ◽  
3 Tesla Mri
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