Successful Eradication of a Monoclonal Strain ofKlebsiella pneumoniaeduring aK. pneumoniaeCarbapenemase-ProducingK. pneumoniaeOutbreak in a Surgical Intensive Care Unit in Miami, Florida

2010 ◽  
Vol 31 (10) ◽  
pp. 1074-1077 ◽  
Author(s):  
L. Silvia Munoz-Price ◽  
Carolina De La Cuesta ◽  
Stephen Adams ◽  
Mary Wyckoff ◽  
Timothy Cleary ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Klebsiella Pneumoniae ◽  
Surgical Intensive Care Unit ◽  
Surgical Intensive Care ◽  
Horizontal Spread ◽  
And Control

We describe the investigation and control of aKlebsiella pneumoniaecarbapenemase-producingK. pneumoniaeoutbreak in a 20-bed surgical intensive care unit during the period from January 1, 2009 through January 1, 2010. Nine patients were either colonized or infected with a monoclonal strain ofK. pneumoniae.The implementation of a bundle of interventions on July 2009 successfully controlled the further horizontal spread of this organism.

Effectiveness of Surveillance of Central Catheter-Related Bloodstream Infection in an ICU in Korea

2001 ◽  
Vol 22 (7) ◽  
pp. 433-436 ◽  
Author(s):  
Sunmi Yoo ◽  
Mina Ha ◽  
Daeok Choi ◽  
Hyunjoo Pai
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Infection Control ◽  
Intervention Group ◽  
Surgical Intensive Care Unit ◽  
Control Group ◽  
Intervention Period ◽  
Active Infection ◽  
Surgical Intensive Care ◽  
And Control

AbstractObjective:To determine whether surveillance and infection control interventions decrease the incidence of catheter-related (CR) bloodstream infections (BSIs) in Korea.Setting:A medical-surgical intensive care unit (ICU) of a university hospital in Korea.Design:The CR infection rate of the intervention period was compared to that of historical controls for a 4-month period.Patients:All patients with a central venous catheter in the intensive care unit (ICU) from October 1998 to January 1999.Methods:Active infection control programs were initiated during the intervention period. Data collected included patient characteristics, risk factors of CR infection, and the microbiology laboratory results. Laboratory-proven CR infection rates were compared between the intervention group and control group.Results:304 catheters were inserted into 248 patients. The intervention group and the control group showed similar characteristics, but more patients in the intervention group received steroid therapy, and subclavian insertion was more common in the intervention group. CR BSI occurred in 1.3 per 1,000 catheter-days in the intervention group and 4.2 in the control group (binomial test, P=.14). CR infections were associated with the duration of ICU admission by multivariate logistic regression.Conclusions:The data suggested that an active infection surveillance and control program could reduce the rate of CR BSI in an ICU.

scholarly journals Risk Factors for Carbapenem Resistant Klebsiella pneumoniae Hospital Infection in the Intensive Care Unit

2018 ◽  
Vol 19 (3) ◽  
pp. 255-261
Author(s):  
Zorana M. Djordjevic ◽  
Marko M. Folic ◽  
Nevena Gajovic ◽  
Slobodan M. Jankovic
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Logistic Regression ◽  
Intensive Care ◽  
Klebsiella Pneumoniae ◽  
Surgical Intensive Care Unit ◽  
Multivariate Logistic Regression ◽  
Surgical Intensive Care ◽  
Carbapenem Resistant

Abstract Carbapenem-resistant Klebsiella pneumoniae (CR-Kp) has become a major threat to patients in hospitals, increasing mortality, length of stay and costs. The aim of this study was to discover risk factors for the development of hospital infections (HIs) caused by CR-Kp. A prospective cohort study was conducted in the Medical-Surgical Intensive Care Unit of the Clinical Centre in Kragujevac, Kragujevac, Serbia, from January 1, 2011, to December 31, 2015. The “cases” were patients with HIs caused by CR-Kp, while the “controls” were patients infected with carbapenem-sensitive Klebsiella pneumoniae (CS-Kp). The significance of multiple putative risk factors for HIs caused by CR-Kp was tested using multivariate logistic regression. Although univariate analyses pointed to many risk factors, with a significant influence on the occurrence of hospital CR-Kp infections, the multivariate logistic regression identified five independent risk factors: use of mechanical ventilation (OR=6.090; 95% CI=1.030-36.020; p=0.046); length of antibiotic therapy before HIs (days) (OR=1.080; 95% CI=1.003-1.387; p=0.045); previous use of carbapenems (OR=7.005; 95% CI=1.054-46.572; p=0.044); previous use of ciprofloxacin (OR=20.628; 95% CI=2.292-185.687; p=0.007) and previous use of metronidazole (OR=40.320; 95% CI=2.347-692.795; p=0.011) HIs caused by CR-Kp are strongly associated with the use of mechanical ventilation and the duration of the previous use of certain antibiotics (carbapenems, ciprofloxacin and metronidazole).

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