scholarly journals Causes of Death in HIV‐1–Infected Patients Treated with Antiretroviral Therapy, 1996–2006: Collaborative Analysis of 13 HIV Cohort Studies

2010 ◽  
Vol 50 (10) ◽  
pp. 1387-1396 ◽  
Keyword(s):  
Antiretroviral Therapy ◽  
Cohort Studies ◽  
Causes Of Death ◽  
Collaborative Analysis ◽  
Hiv 1

scholarly journals Association of Suboptimal Antiretroviral Therapy Adherence With Inflammation in Virologically Suppressed Individuals Enrolled in the SMART Study

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Jose R Castillo-Mancilla ◽  
Andrew N Phillips ◽  
James D Neaton ◽  
Jacqueline Neuhaus ◽  
Simon Collins ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Confidence Interval ◽  
Cohort Studies ◽  
Plasma Concentrations ◽  
Virologic Suppression ◽  
Art Adherence ◽  
Antiretroviral Therapy Adherence ◽  
Smart Study ◽  
Hiv 1 ◽  
D Dimer

Abstract Suboptimal (ie, <100%) antiretroviral therapy (ART) adherence has been associated with heightened inflammation in cohort studies, even among people with virologic suppression. We aimed to evaluate this association among participants in the Strategies for Management of Antiretroviral Therapy (SMART) study who had virologic suppression (HIV-1 VL < 200 copies/mL) at enrollment. Based on self-reported adherence (7-day recall), plasma concentrations of interleukin 6 and D-dimer were 9% (95% confidence interval [CI], 1%–18%; P = .02) and 11% (95% CI, 1%–22%; P = .03) higher in participants who reported suboptimal vs 100% adherence, respectively. These findings confirm previous observations and support the hypothesis that suboptimal ART adherence, even in the context of virologic suppression, may have significant biological consequences. ClinicalTrials.gov number NCT00027352

Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: a collaborative analysis of prospective studies

The Lancet ◽  
2002 ◽  
Vol 360 (9327) ◽  
pp. 119-129 ◽  
Author(s):  
Matthias Egger ◽  
Margaret May ◽  
Geneviève Chêne ◽  
Andrew N Phillips ◽  
Bruno Ledergerber ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Prospective Studies ◽  
Highly Active Antiretroviral Therapy ◽  
Highly Active ◽  
Collaborative Analysis ◽  
Hiv 1

scholarly journals Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies

2017 ◽  
Vol 4 (8) ◽  
pp. e349-e356 ◽  
Author(s):  
Adam Trickey ◽  
Margaret T May ◽  
Jorg-Janne Vehreschild ◽  
Niels Obel ◽  
M John Gill ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Cohort Studies ◽  
Hiv Positive ◽  
Collaborative Analysis
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