Association between Patient Age and Influenza A Subtype during Influenza Outbreaks

2010 ◽  
Vol 31 (05) ◽  
pp. 535-537 ◽  
Author(s):  
Bonita E. Lee ◽  
Shamir N. Mukhi ◽  
Steven J. Drews

The distribution of influenza A subtypes was studied in specimens recovered from patients in long-term care facility (LTCF) outbreaks and in non-LTCF outbreaks in Alberta, Canada, for 3 years before the influenza pandemic of 2009. We found that H3 but not HI was associated with infection in older adults. Therefore, H3 was more commonly found than HI in outbreaks in LTCFs.

2009 ◽  
Vol 15 (12) ◽  
pp. 1973-1976 ◽  
Author(s):  
Nila J. Dharan ◽  
Monica Patton ◽  
Alicia M. Siston ◽  
Julie Morita ◽  
Enrique Ramirez ◽  
...  

Author(s):  
José-Manuel Ramos-Rincón ◽  
Máximo Bernabeu-Whittel ◽  
Isabel Fiteni-Mera ◽  
Almudena López-Sampalo ◽  
Carmen López-Ríos ◽  
...  

Abstract Background COVID-19 severely impacted older adults and long-term care facility (LTCF) residents. Our primary aim was to describe differences in clinical and epidemiological variables, in-hospital management, and outcomes between LTCF residents and community-dwelling older adults hospitalized with COVID-19. The secondary aim was to identify risk factors for mortality due to COVID-19 in hospitalized LTCF residents. Methods This is a cross-sectional analysis within a retrospective cohort of hospitalized patients≥75 years with confirmed COVID-19 admitted to 160 Spanish hospitals. Differences between groups and factors associated with mortality among LTCF residents were assessed through comparisons and logistic regression analysis. Results Of 6,189 patients≥75 years, 1,185 (19.1%) were LTCF residents and 4,548 (73.5%) were community-dwelling. LTCF residents were older (median: 87.4 vs. 82.1 years), mostly female (61.6% vs. 43.2%), had more severe functional dependence (47.0% vs 7.8%), more comorbidities (Charlson Comorbidity Index: 6 vs 5), had dementia more often (59.1% vs. 14.4%), and had shorter duration of symptoms (median: 3 vs 6 days) than community-dwelling patients (all, p<.001). Mortality risk factors in LTCF residents were severe functional dependence (aOR:1.79;95%CI:1.13-2.83;p=.012), dyspnea (1.66;1.16-2.39;p=.004), SatO2<94% (1.73;1.27-2.37;p=.001), temperature≥37.8ºC (1.62;1.11-2.38; p=.013); qSOFA index≥2 (1.62;1.11-2.38;p=.013), bilateral infiltrates (1.98;1.24-2.98;p<.001), and high C-reactive protein (1.005;1.003-1.007;p<.001). In-hospital mortality was initially higher among LTCF residents (43.3% vs 39.7%), but lower after adjusting for sex, age, functional dependence, and comorbidities (aOR:0.74,95%CI:0.62-0.87;p<.001). Conclusion Basal functional status and COVID-19 severity are risk factors of mortality in LTCF residents. The lower adjusted mortality rate in LTCF residents may be explained by earlier identification, treatment, and hospitalization for COVID-19.


2010 ◽  
Vol 31 (12) ◽  
pp. 1300-1302 ◽  
Author(s):  
David C. Alexander ◽  
Anne-Luise Winter ◽  
AliReza Eshaghi ◽  
Kathleen Dooling ◽  
Crystal Frenette ◽  
...  

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