scholarly journals Cytokine Profiles Induced by the Novel Swine‐Origin Influenza A/H1N1 Virus: Implications for Treatment Strategies

2010 ◽  
Vol 201 (3) ◽  
pp. 346-353 ◽  
Author(s):  
Patrick C. Y. Woo ◽  
Edward T. K. Tung ◽  
Kwok‐Hung Chan ◽  
Candy C. Y. Lau ◽  
Susanna K. P. Lau ◽  
...  
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
Treatment Strategies ◽  
The Novel ◽  
Cytokine Profiles ◽  
Influenza A H1n1

scholarly journals The mutation network for the hemagglutinin gene from the novel influenza A (H1N1) virus

2009 ◽  
Vol 54 (13) ◽  
pp. 2168-2170 ◽  
Author(s):  
YunGang He ◽  
GuoHui Ding ◽  
Chao Bian ◽  
Zhong Huang ◽  
Ke Lan ◽  
...  
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
The Novel ◽  
Influenza A H1n1 ◽  
Hemagglutinin Gene ◽  
Novel Influenza A

scholarly journals Subclinical Infection with the Novel Influenza A (H1N1) Virus

2009 ◽  
Vol 49 (10) ◽  
pp. 1622-1623 ◽  
Author(s):  
Jian Yang ◽  
Fan Yang ◽  
Fang Huang ◽  
Jianwei Wang ◽  
Qi Jin
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
The Novel ◽  
Subclinical Infection ◽  
Influenza A H1n1 ◽  
Novel Influenza A

scholarly journals Effect of the Novel Influenza A (H1N1) Virus in the Human Immune System

PLoS ONE ◽  
2009 ◽  
Vol 4 (12) ◽  
pp. e8393 ◽  
Author(s):  
Evangelos J. Giamarellos-Bourboulis ◽  
Maria Raftogiannis ◽  
Anastasia Antonopoulou ◽  
Fotini Baziaka ◽  
Pantelis Koutoukas ◽  
...  
Keyword(s):  
Immune System ◽  
Influenza A ◽  
H1n1 Virus ◽  
The Novel ◽  
Human Immune System ◽  
Influenza A H1n1 ◽  
Human Immune ◽  
Novel Influenza A

scholarly journals Immunophenotype Expressions and Cytokine Profiles of Influenza A H1N1 Virus Infection in Pediatric Patients in 2009

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Shih-Min Wang ◽  
Yu-Ting Liao ◽  
Yu-Shiang Hu ◽  
Tzong-Shiann Ho ◽  
Ching-Fen Shen ◽  
...  
Keyword(s):  
Influenza A ◽  
Pediatric Patients ◽  
Mononuclear Cells ◽  
H1n1 Virus ◽  
Influenza Pandemic ◽  
Influenza Infection ◽  
Plasma Concentrations ◽  
Pulmonary Complications ◽  
Cytokine Profiles ◽  
Influenza A H1n1

Background. A novel swine-origin influenza A H1N1 virus (S-OIV) caused human infection and acute respiratory illness in 2009, resulting in an influenza pandemic.Objectives. This study characterized the immune responses of S-OIV infection in pediatric patients at risk of pulmonary complications.Methods. All enrolled pediatric patients were confirmed virologically for S-OIV infection in 2009-2010, prospectively. Changes in cellular immunophenotypes were analyzed using flow cytometry. Plasma cytokine levels associated with S-OIV infection by pulmonary and without pulmonary complications were measured using cytokine cytometric bead assay kits.Results. A total of 85 patients with a mean age of 10.3 years were recruited. The level of C-reactive protein (CRP) was high in patients exhibiting pulmonary complications. The percentage of cellular immunophenotypes did not change between patients with and without pulmonary complications. The absolute numbers of peripheral blood mononuclear cells (PBMC), CD3, CD8, and CD16CD56 decreased with acute S-OIV pulmonary complications. Acute influenza infection with pulmonary complications was associated with high plasma concentrations of IL-1β, IL-6, IL-12, and IFN-γ.Conclusion. Immunophenotype studies have reported variability in immune response to the severity of S-OIV infections. Acute phase cytokine profiles of the 2009 S-OIV infection might have contributed to the pathogenesis of the pulmonary complications.

scholarly journals Effect of the novel influenza A (H1N1) virus in the human immune system

Critical Care ◽  
2009 ◽  
Vol 13 (Suppl 4) ◽  
pp. P24
Author(s):  
A Antonopoulou ◽  
M Raftogiannis ◽  
F Baziaka ◽  
P Koutoukas ◽  
A Savva ◽  
...  
Keyword(s):  
Immune System ◽  
Influenza A ◽  
H1n1 Virus ◽  
The Novel ◽  
Human Immune System ◽  
Influenza A H1n1 ◽  
Human Immune ◽  
Novel Influenza A

scholarly journals The novel influenza A (H1N1) virus pandemic: An update

2009 ◽  
Vol 4 (4) ◽  
pp. 163 ◽  
Author(s):  
N Petrosillo ◽  
S Di Bella ◽  
CM Drapeau ◽  
E Grilli
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
The Novel ◽  
Influenza A H1n1 ◽  
Novel Influenza A
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