Clostridium difficile -Associated Disease in Long-Term Care Facilities

1990 ◽  
Vol 11 (8) ◽  
pp. 434-438 ◽  
Author(s):  
David W. Bentley

Clostridium difficile is a major cause of gastrointestinal infections. In 1978, Bartlett and colleagues identified C difficile and its toxin as the cause of the antibiotic-associated pseudomembranous colitis (PMC). Within a few years, there was the development of a diagnostic assay, a description of a clinical and pathological spectrum of the disease, a definition of risk factors and characterization of the two toxins that account for the pathological event. Additional information regarding the microbiology, pathogenesis, clinical manifestations, diagnosis and treatment has rapidly developed. These features are beyond the scope of this report, and the reader is referred to several recent reviews.

2021 ◽  
Vol 26 (48) ◽  
Author(s):  
Françoise Renard ◽  
Aline Scohy ◽  
Johan Van der Heyden ◽  
Ilse Peeters ◽  
Sara Dequeker ◽  
...  

Background COVID-19-related mortality in Belgium has drawn attention for two reasons: its high level, and a good completeness in reporting of deaths. An ad hoc surveillance was established to register COVID-19 death numbers in hospitals, long-term care facilities (LTCF) and the community. Belgium adopted broad inclusion criteria for the COVID-19 death notifications, also including possible cases, resulting in a robust correlation between COVID-19 and all-cause mortality. Aim To document and assess the COVID-19 mortality surveillance in Belgium. Methods We described the content and data flows of the registration and we assessed the situation as of 21 June 2020, 103 days after the first death attributable to COVID-19 in Belgium. We calculated the participation rate, the notification delay, the percentage of error detected, and the results of additional investigations. Results The participation rate was 100% for hospitals and 83% for nursing homes. Of all deaths, 85% were recorded within 2 calendar days: 11% within the same day, 41% after 1 day and 33% after 2 days, with a quicker notification in hospitals than in LTCF. Corrections of detected errors reduced the death toll by 5%. Conclusion Belgium implemented a rather complete surveillance of COVID-19 mortality, on account of a rapid investment of the hospitals and LTCF. LTCF could build on past experience of previous surveys and surveillance activities. The adoption of an extended definition of ‘COVID-19-related deaths’ in a context of limited testing capacity has provided timely information about the severity of the epidemic.


2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S182-S182
Author(s):  
Suganya Chandramohan ◽  
Amar Krishna ◽  
Parminder Virdi ◽  
Jordon Polistico ◽  
Nikhila Thammineni ◽  
...  

2020 ◽  
Vol 48 (10) ◽  
pp. 1144-1147
Author(s):  
Eva Leitner ◽  
Elisabeth Schreiner ◽  
Maria Neuhold ◽  
Michael Bozic ◽  
Christian Pux ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document