Nosocomial Infection Rates at an Oncology Center

1988 ◽  
Vol 9 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Coleman Rotstein ◽  
K. Michael Cummings ◽  
Andreas L. Nicolaou ◽  
Joyce Lucey ◽  
John Fitzpatrick
Keyword(s):  
Nosocomial Infection ◽  
Nosocomial Infections ◽  
Blood Stream ◽  
Myelogenous Leukemia ◽  
Infection Rates ◽  
Coagulase Negative Staphylococci ◽  
Underlying Malignancy ◽  
Acute Myelogenous ◽  
Tract Infections ◽  
Oncology Center

AbstractNosocomial infection rates were computed for 5,031 patients at an oncology center during a 20-month period. Twelve percent of the patients developed nosocomial infections, accounting for a total of 802 infections. The overall incidence of nosocomial infections during this study period was 6.27 infections per 1,000 patient days. The highest incidence of nosocomial infections was found in patients having acute myelogenous leukemia (30.49 infections per 1,000 patient days); bone and joint cancer (27.27 infections per 1,000 patient days); and liver cancer (26.58 infections per 1,000 patient days). The respiratory tract was the most common site of infection, followed by blood-stream, surgical wound, and urinary tract infections. Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, and coagulase-negative staphylococci were most frequently implicated as pathogens. The distribution of specific types of infection according to underlying malignancy was also tabulated. These data provide nosocomial infection rates, common pathogens, and sites of infection for cancer patients, thus assisting in directing appropriate therapy for these patients.

scholarly journals NUTRITIONALLY VARIANT STREPTOCOCCI BACTEREMIA IN CANCER PATIENTS: A RETROSPECTIVE STUDY, 1999-2014

2015 ◽  
Vol 7 ◽  
pp. e2015030 ◽  
Author(s):  
Abraham Tareq Yacoub ◽  
Jayasree Krishnan ◽  
Ileana M. Acevedo ◽  
Joseph Halliday ◽  
John Norman Greene
Keyword(s):  
Cancer Patients ◽  
Clinical Characteristics ◽  
Blood Stream Infection ◽  
Hematologic Malignancies ◽  
Blood Stream ◽  
Lymphocytic Leukemia ◽  
Myelogenous Leukemia ◽  
Cancer Center ◽  
Underlying Malignancy ◽  
Acute Myelogenous

BackgoundNutritionally variant Streptococci (NVS), Abiotrophia and Granulicatella are implicated in causing endocarditis and blood stream infections more frequently than other sites of infection. Neutropenia and mucositis are the most common predisposing factors for infection with other pathogens in cancer patients. In this study we investigated the clinical characteristics of NVS bacteremia in cancer patients and identified risk factors and outcomes associated with these infections. Materials and MethodsWe retrospectively reviewed all cases of NVS bacteremia occurring from June 1999 to April 2014 at H. Lee Moffitt Cancer Center and Research Institute. The computerized epidemiology report provided by the microbiology laboratory identified thirteen cancer patients with NVS bacteremia. We collected data regarding baseline demographics and clinical characteristics such as age, sex, underlying malignancy, neutropenic status, duration of neutropenia, treatment, and outcome.ResultsThirteen patients were identified with positive NVS blood stream infection. Ten patients (77%) had hematologic malignancies, including chronic lymphocytic leukemia (CLL) (1), multiple myeloma (MM) (1), acute myelogenous leukemia (AML) (4), and non Hodgkin’s lymphoma (NHL) (4).  The non-hematologic malignancies included esophageal cancer (2) and bladder cancer (1).ConclusionNVS should be considered as a possible agent of bacteremia in cancer patients with neutropenia and a breach in oral, gastrointestinal and genitourinary mucosa (gingivitis/mucositis).

scholarly journals Device-Associated Nosocomial Infection Rates in Intensive Care Units of Argentina

2004 ◽  
Vol 25 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Victor Daniel Rosenthal ◽  
Sandra Guzmán ◽  
Christopher Crnich
Keyword(s):  
Developing Countries ◽  
Intensive Care ◽  
Nosocomial Infection ◽  
Infection Control ◽  
Nosocomial Infections ◽  
Public Health Problem ◽  
Infection Rates ◽  
Infection Control Program ◽  
Surgical Icus ◽  
Tract Infections

AbstractBackground:Nosocomial infections are an important public health problem in many developing countries, particularly in the intensive care unit (ICU) setting. No previous data are available on the incidence of device-associated nosocomial infections in different types of ICUs in Argentina.Methods:We performed a prospective nosocomial infection surveillance study during the first year of an infection control program in six Argentinean ICUs. Nosocomial infections were identified using the Centers for Disease Control and Prevention National Nosocomial Infections Surveillance System definitions, and site-specific nosocomial infection rates were calculated.Results:The rate of catheter-associated bloodstream infections in medical-surgical ICUs was 30.3 per 1,000 device days; it was 14.2 per 1,000 device-days in coronary care units (CCUs). The rate of ventilator-associated pneumonia in medical-surgical ICUs was 46.3 per 1,000 device-days; it was 45.5 per 1,000 device-days in CCUs. The rate of symptomatic catheter-associated urinary tract infections in medical-surgical ICUs was 18.5 per 1,000 device-days; it was 12.1 per 1,000 device-days in CCUs.Conclusion:The high rate of nosocomial infections in Argentinean ICUs found during our surveillance suggests that ongoing targeted surveillance and implementation of proven infection control strategies is needed in developing countries such as Argentina.

Nosocomial Infections Among Neonates in High-risk Nurseries in the United States

PEDIATRICS ◽  
1996 ◽  
Vol 98 (3) ◽  
pp. 357-361 ◽  
Author(s):  
Robert P. Gaynes ◽  
Jonathan R. Edwards ◽  
William R. Jarvis ◽  
David H. Culver ◽  
James S. Tolson ◽  
...  
Keyword(s):  
Birth Weight ◽  
High Risk ◽  
Nosocomial Infection ◽  
Nosocomial Infections ◽  
Bloodstream Infections ◽  
Infection Site ◽  
Group B Streptococci ◽  
Coagulase Negative Staphylococci ◽  
Group B ◽  
Weight Groups

Background. Nosocomial infections result in considerable morbidity and mortality among neonates in high-risk nurseries (HRNs). Purpose. To examine the epidemiology of nosocomial infections among neonates in level III HRNs. Methods. Data were collected from 99 hospitals with HRNs participating in the National Nosocomial Infections Surveillance system, which uses standard surveillance protocols and nosocomial infection site definitions. The data included information on maternal acquisition of and risk factors for infection, such as device exposure, birth weight category (≤1000, 1001 through 1500, 1501 through 2500, and >2500 g), mortality, and the relationship of the nosocomial infection to death. Results. From October 1986 through September 1994, these hospitals submitted data on 13 179 nosocomial infections. The bloodstream was the most frequent site of nosocomial infection in all birth weight groups. Nosocomial pneumonia was the second most common infection site, followed by the gastrointestinal and eye, ear, nose, and throat sites. The most common nosocomial pathogens among all neonates were coagulase-negative staphylococci, Staphylococcus aureus, enterococci, Enterobacter sp, and Escherichia coli. Group B streptococci were associated with 46% of bloodstream infections that were maternally acquired; coagulase-negative staphylococci were associated with 58% of bloodstream infections that were not maternally acquired, most of which (88%) were associated with umbilical or central intravenous catheters. Conclusions. Bloodstream infections, the most frequent nosocomial infections in all birth weight groups, should be a major focus of surveillance and prevention efforts in HRNs. For bloodstream infections, stratification of surveillance data by maternal acquisition will help focus prevention efforts for group B streptococci outside the HRN. Within the nursery, bloodstream infection surveillance should focus on umbilical or central intravenous catheter use, a major risk factor for infection.

Device-Associated Nosocomial Infection Rates in Turkish Medical-Surgical Intensive Care Units

2006 ◽  
Vol 27 (4) ◽  
pp. 343-348 ◽  
Author(s):  
Dilara Inan ◽  
Rabin Saba ◽  
Ata Nevzat Yalcin ◽  
Murat Yilmaz ◽  
Gozde Ongut ◽  
...  
Keyword(s):  
Intensive Care ◽  
Urinary Tract ◽  
Nosocomial Infection ◽  
Infection Rate ◽  
Nosocomial Infections ◽  
University Hospital ◽  
Infection Rates ◽  
Surgical Intensive Care ◽  
The Mean ◽  
Device Associated Infection

Objective.To describe the incidence of device-associated nosocomial infections in medical-surgical intensive care units (MS ICUs) in a university hospital in Turkey and compare it with National Nosocomial Infections Surveillance (NNIS) system rates.Design.Prospective surveillance study during a period of 27 months. Device utilization ratios and device-associated infection rates were calculated using US Centers for Disease Control and Prevention and NNIS definitions.Setting.Two separate MS ICUs at Akdeniz University Hospital, Antalya, Turkey.Patients.All patients were included who presented with no signs and symptoms of infection within the first 48 hours after admission.Results.Data on 1,985 patients with a total of 16,892 patient-days were analyzed. The mean overall infection rate per 100 patients was 29.1 infections, and the mean infection rate per 1,000 patient-days was 34.2 infections. The rate of ventilator-associated pneumonia was 20.76 infections per 1,000 ventilator-days, the rate of catheter-associated urinary tract infection was 13.63 infections per 1,000 urinary catheter–days, and the rate of catheter-associated bloodstream infection was 9.69 infections per 1,000 central line–days. The most frequently isolated pathogens were Pseudomonas species among patients with ventilator-associated pneumonias (35.8% of cases), Candida species among patients with catheter-associated urinary tract infections (37.1% of cases), and coagulase-negative staphylococci among patients with catheter-associated bloodstream infections (20.0% of cases).Conclusion.We found both higher device-associated infection rates and higher device utilization ratios in our MS ICUs than those reported by the NNIS system. To reduce the rate of infection, implementation of infection control practices and comprehensive education are required, and an appropriate nationwide nosocomial infection and control system is needed in Turkey.

A Decade of Prevalence Surveys in a Tertiary-Care Center: Trends in Nosocomial Infection Rates, Device Utilization, and Patient Acuity

1999 ◽  
Vol 20 (8) ◽  
pp. 543-548 ◽  
Author(s):  
Jeffrey W. Weinstein ◽  
Dorothy Mazon ◽  
Elizabeth Pantelick ◽  
Patricia Reagan-Cirincione ◽  
Louise M. Dembry ◽  
...  
Keyword(s):  
Nosocomial Infection ◽  
Bloodstream Infection ◽  
Acute Care ◽  
Nosocomial Infections ◽  
Tertiary Care ◽  
Infection Rates ◽  
Nosocomial Bloodstream Infection ◽  
Abnormal Laboratory ◽  
Infection Surveillance ◽  
The Mean

AbstractObjective:To evaluate the usefulness of repeated prevalence surveys to determine trends in the rates of nosocomial infections and to detect changes in risk factors (eg, use of invasive devices) associated with nosocomial infections.Patients And Methods:Ten annual prevalence surveys were conducted by trained infection control practitioners between 1985 and 1995 for acute-care patients on the medical, surgical, pediatric, and obstetric-gynecologic services at a 900-bed, tertiary-care, teaching hospital with 750 acute-care beds. The same methods of chart review and concurrent reporting from nursing, the microbiology and clinical laboratory, and the pharmacy were used each year to collect data on the prevalence of nosocomial infections, invasive-device utilization, and abnormal laboratory indicators. Although data were collected on a single day, a period-prevalence study approach was used, because charts were reviewed for any infection data occurring within the 7 days prior to the survey.Results:The hospital census for acute-care patients, as measured by the prevalence surveys, declined sharply over the 10 years, from 673 to 575 patients (P=.02). However, the medical service census increased from 150 to 188 patients (P=.01). During the same period, there was a significant decrease in the mean length of stay, from 7.3 to 6.0 days (P=.01), and a concomitant increase in the mean diagnosis-related-group case-mix index, from 1.03 to 1.24 (P=.001). Overall, nosocomial infection rates remained unchanged over the study period (mean of 9.85 infections per 100 patients), but rates of nosocomial bloodstream infection increased from 0.0% in 1985 to 2.3% in 1995 (P=.05). Nosocomial infection rates were significantly higher on the medical and surgical services than on other services (P<.001). Utilization rates increased significantly for Foley catheters (9.0% to 16.0%, P=.002) and ventilators (5.0% to 8.0%, P=.05).Conclusions:Despite apparent increases in the severity of illness of our patients, overall rates of nosocomial infection remained stable during a decade of study. Rates of nosocomial bloodstream infection increased, in parallel with National Nosocomial Infection Surveillance System data. We found repeated prevalence surveys to be useful in following trends and rates of infection, device utilization, and abnormal laboratory values among patients at our institution. Such methodologies can be valuable and low-cost components of a comprehensive infection surveillance, prevention, and control program and other potential quality-improvement initiatives, because they enable better annual planning of departmental strategies to meet hospital needs

Multicenter Study of the Prevalence of Nosocomial Infections in Italian Hospitals

2004 ◽  
Vol 25 (1) ◽  
pp. 85-87 ◽  
Author(s):  
Carlo Di Pietrantonj ◽  
Lorenza Ferrara ◽  
G. Lomolino
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Multicenter Study ◽  
Nosocomial Infections ◽  
Point Prevalence ◽  
Prevalence Study ◽  
Infection Rates ◽  
Point Prevalence Study ◽  
Tract Infections

AbstractA point-prevalence study of nosocomial infections was conducted in 10 generai hospitals in northwestern Italy in June and July 2000. Infection rates were compared by type and site among the different hospitals. Urinary tract infections were most frequent, accounting for 57.8% of 128 nosocomial infections.

Handwashing Program for the Prevention of Nosocomial Infections in a Neonatal Intensive Care Unit

2004 ◽  
Vol 25 (9) ◽  
pp. 742-746 ◽  
Author(s):  
Sau-Pin Won ◽  
Hung-Chieh Chou ◽  
Wu-Shiun Hsieh ◽  
Chien-Yi Chen ◽  
Shio-Min Huang ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Hand Hygiene ◽  
Nosocomial Infection ◽  
Respiratory Tract ◽  
Neonatal Intensive Care Unit ◽  
Nosocomial Infections ◽  
Neonatal Intensive Care ◽  
Statistical Significance ◽  
Tract Infections

AbstractObjective:To evaluate the effects of a hand hygiene program on compliance with hand hygiene and the rate of nosocomial infections in a neonatal intensive care unit (NICU).Design:Open trial.Setting:A level-III NICU in a teaching hospital.Participants:Nurses, physicians, and other healthcare workers in the NICU.Interventions:A multimodal campaign for hand hygiene promotion was conducted beginning in September 1998. This program consisted of formal lectures, written instructions and posted reminders regarding hand hygiene and proper handwashing techniques, covert observation, financial incentives, and regular group feedback on compliance. Surveillance of handwashing compliance and nosocomial infections before and during the program was analyzed.Results:Overall compliance with hand hygiene improved from 43% at baseline to 80% during the promotion program. The rate of nosocomial infections decreased from 15.13 to 10.69 per 1,000 patient-days (P = .003) with improved handwashing compliance. In particular, respiratory tract infections decreased from 3.35 to 1.06 per 1,000 patient-days during the handwashing campaign (P = .002). Furthermore, the correlation between nosocomial infection of the respiratory tract and handwashing compliance also reached statistical significance (r = -0.385; P = .014).Conclusions:Improved compliance with handwashing was associated with a significant decrease in overall rates of nosocomial infection and respiratory infections in particular. Washing hands is a simple, economical, and effective method for preventing nosocomial infections in the NICU

Risk factors for bacteremia and central line-associated blood stream infections in children with acute myelogenous leukemia: A single-institution report

2016 ◽  
Vol 64 (3) ◽  
pp. e26254 ◽  
Author(s):  
Ashley E. J. Rogers ◽  
Kristen M. Eisenman ◽  
Susan A. Dolan ◽  
Kristin M. Belderson ◽  
Jocelyn R. Zauche ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Myelogenous Leukemia ◽  
Blood Stream ◽  
Central Line ◽  
Myelogenous Leukemia ◽  
Single Institution ◽  
Blood Stream Infections ◽  
Acute Myelogenous

scholarly journals Control and prevention of nosocomial infection

2020 ◽  
Vol 7 (7) ◽  
pp. 2528
Author(s):  
Palle Lokhnah Reddy ◽  
Aluka Anand Chand
Keyword(s):  
Nosocomial Infection ◽  
Nosocomial Infections ◽  
Great Majority ◽  
Blood Stream ◽  
Blood Stream Infections ◽  
Hospital Acquired Infection ◽  
Infection Surveillance ◽  
Control And Prevention ◽  
Prevention Of Nosocomial Infection ◽  
Hospital Acquired

Background: The center for disease control and prevention estimates that 1.5 million people suffer from hospital acquired infection every year and hereby one lack people die. Major nosocomial infections (NIs) are ventilator associated pneumonia (VAP), urinary tract infection (UTI), surgical site infection (SSI) and blood stream infections (BSI).Methods: This was a retrospective multicenter descriptive study involving 2000 consecutive patients in ICU for a period of 2 years. The data was compared with the data available from National Nosocomial infection surveillance. NIs were analyzed by infection site and pathogen distribution.Results: The main factors responsible for NI are both hospital and patients. Almost 40% UTI’s contribute to NI’s, 30% VAP’s, 20% SSI and 10% BSI respectively. Nosocomial infections can be reduced by better surveillance system and infection control. Primary blood stream infections, pneumonia and UTI associated with invasive devises made up the great majority of nosocomial infections.Conclusion: We can reduce NI’s by proper use and care of urine catheters, proper use and care of vascular accesses lines, by proper surveillance of surgical procedure and by proper hand and hygiene standard precautions.

scholarly journals Lesson learned from the pandemic: Isolation and hygiene measures for COVID-19 could reduce the nosocomial infection rates in oncology wards

2021 ◽  
pp. 107815522110438
Author(s):  
Deniz C Guven ◽  
Imdat Eroglu ◽  
Rashad Ismayilov ◽  
Ege Ulusoydan ◽  
Oktay H Aktepe ◽  
...  
Keyword(s):  
Nosocomial Infection ◽  
Nosocomial Infections ◽  
Time Frame ◽  
Interquartile Range ◽  
Infection Rates ◽  
Palliative Oncology ◽  
Hygiene Measures ◽  
Different Types ◽  
Palliative Care Units ◽  
Intraabdominal Infections

Introduction It was previously demonstrated that seasonal influenza incidence was significantly decreased during the COVID-19 pandemic, possibly due to respiratory and hygiene precautions. From this point, we hypothesized that the COVID-19 precautions could lead to a decrease in nosocomial infection rates in oncology inpatient wards. Methods We evaluated the nosocomial infection rates in an inpatient palliative oncology ward in the first 3 months of the COVID-19 pandemic in our country and compared this rate with the same time frame of the previous year in our institution. Results The percentage of nosocomial infections complicating the hospitalization episodes were significantly reduced in the first 3 months of the pandemic compared to the previous year (43 vs. 55 nosocomial infection episodes; 18.6% vs. 32.2%, p = 0.002). The decrease in the nosocomial infections was consistent in the different types of infections, namely pneumonia (4.8% vs. 7.6%), urinary tract infection (5.2% vs. 7.6%), bacteremia (5.2% vs. 7%) and intraabdominal infections (2.6% vs. 3.5%). The median monthly disinfectant use was significantly increased to 98 liters (interquartile range: 82 – 114) in 2020 compared to 72 L (interquartile range: 36 – 72) in 2019 ( p = 0.046). Conclusion The continuation of the simple and feasible hygiene and distancing measures for healthcare workers and patient relatives and adaptations for earlier discharge could be beneficial for preventing nosocomial infections in oncology wards. These measures could be implemented routinely even after the COVID-19 pandemic for patient safety, especially in settings with higher nosocomial infection rates like inpatients palliative care units.

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