scholarly journals HIV‐1 Infection in Zambian Children Impairs the Development and Avidity Maturation of Measles Virus–Specific Immunoglobulin G after Vaccination and Infection

2009 ◽  
Vol 200 (7) ◽  
pp. 1031-1038 ◽  
Author(s):  
Nitya Nair ◽  
William J. Moss ◽  
Susana Scott ◽  
Nanthalile Mugala ◽  
Zaza M. Ndhlovu ◽  
...  
Keyword(s):  
Immunoglobulin G ◽  
Measles Virus ◽  
Specific Immunoglobulin ◽  
Hiv 1 ◽  
Avidity Maturation

Use of Protein a Conjugated to Peroxidase to Localize Immunoglobulin G in SSPE Ferret Brain

1982 ◽  
Vol 40 ◽  
pp. 350-351
Author(s):  
Hannah R. Brown ◽  
Anthony F. Nostro ◽  
Halldor Thormar
Keyword(s):  
Immunoglobulin G ◽  
Human Disease ◽  
Measles Virus ◽  
Subacute Sclerosing Panencephalitis ◽  
Protein A ◽  
Inflammatory Lesions ◽  
Sspe Virus ◽  
Specific Immunoglobulin ◽  
Antibody Titers ◽  
The Brain

Subacute sclerosing panencephalitis (SSPE) is a slowly progressing disease of the CNS in children which is caused by measles virus. Ferrets immunized with measles virus prior to inoculation with the cell associated, syncytiogenic D.R. strain of SSPE virus exhibit characteristics very similar to the human disease. Measles virus nucleocapsids are present, high measles antibody titers are found in the sera and inflammatory lesions are prominent in the brains. Measles virus specific immunoglobulin G (IgG) is present in the brain,and IgG/ albumin ratios indicate that the antibodies are synthesized within the CNS.

scholarly journals Measles Virus-Specific Immunoglobulin G Isotype Immune Response in Early and Late Infections

2001 ◽  
Vol 39 (1) ◽  
pp. 170-174 ◽  
Author(s):  
M. B. Isa ◽  
L. Martinez ◽  
M. Giordano ◽  
M. Zapata ◽  
C. Passeggi ◽  
...  
Keyword(s):  
Immune Response ◽  
Immunoglobulin G ◽  
Measles Virus ◽  
Specific Immunoglobulin

Measles virus-specific immunoglobulin G subclass response in serum and cerebrospinal fluid

1997 ◽  
Vol 8 (3) ◽  
pp. 233-239 ◽  
Author(s):  
Mitsuo Narita ◽  
Satoshi Yamada ◽  
Yoshihiro Matsuzono ◽  
Osamu Itakura ◽  
Takehiro Togashi ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Immunoglobulin G ◽  
Measles Virus ◽  
Specific Immunoglobulin ◽  
Immunoglobulin G Subclass

scholarly journals Spiramycin Treatment of Toxoplasma gondii Infection in Pregnant Women Impairs the Production and the Avidity Maturation of T. gondii-Specific Immunoglobulin G Antibodies

2009 ◽  
Vol 16 (10) ◽  
pp. 1517-1520 ◽  
Author(s):  
V. Meroni ◽  
F. Genco ◽  
C. Tinelli ◽  
P. Lanzarini ◽  
L. Bollani ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Pregnant Women ◽  
Immunoglobulin G ◽  
Adult Patients ◽  
Control Group ◽  
Igg Antibody ◽  
Specific Immunoglobulin ◽  
Specific Igg ◽  
Toxoplasma Gondii Infection ◽  
Avidity Maturation

ABSTRACT The aim of the study was to evaluate the influence of treatment with spiramycin on the increase of immunoglobulin G (IgG) titers and IgG avidity indexes (AI) in pregnant women with seroconversion from the beginning of therapy until delivery and after delivery. This group was compared with adult patients with recently acquired untreated toxoplasmosis. One hundred four samples from 32 pregnant women with seroconversion for toxoplasmosis and/or very low IgG AI were followed from the beginning of therapy with spiramycin until delivery. Twenty-nine women were further followed some months after delivery and interruption of therapy. Thirty-eight samples from 16 untreated, nonpregnant patients were evaluated as the control group. The Toxoplasma gondii-specific IgG antibody and the T. gondii-specific IgG AI were significantly delayed in pregnant women receiving therapy compared to nonpregnant, untreated controls, and the findings were consistent with the results of assays from two different manufacturers. The T. gondii-specific IgG AI increased in pregnant women after they gave birth. Avidity maturation is delayed during pregnancy and treatment, and low-avidity antibodies in pregnant women within 3 to 4 months cannot be taken as a sign of infection.

scholarly journals Salivary human immunodeficiency virus (HIV)-1-specific immunoglobulin A in HIV-1-exposed infants in Kenya

2008 ◽  
Vol 153 (1) ◽  
pp. 37-43 ◽  
Author(s):  
C. Farquhar ◽  
T. VanCott ◽  
R. Bosire ◽  
C. Bermudez ◽  
D. Mbori-Ngacha ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Immunoglobulin A ◽  
Immunodeficiency Virus ◽  
Specific Immunoglobulin ◽  
Hiv 1

scholarly journals Timing of Development of Measles-Specific Immunoglobulin M and G after Primary Measles Vaccination

1999 ◽  
Vol 6 (2) ◽  
pp. 178-180 ◽  
Author(s):  
Rita F. Helfand ◽  
Senait Kebede ◽  
Howard E. Gary ◽  
Hagos Beyene ◽  
William J. Bellini
Keyword(s):  
Positive Result ◽  
Measles Virus ◽  
Primary Vaccination ◽  
Immunoglobulin M ◽  
Measles Vaccine ◽  
Wild Type ◽  
Specific Antibodies ◽  
Specific Immunoglobulin ◽  
Measles Vaccination ◽  
Antibody Capture

ABSTRACT A standard method for diagnosing measles is to detect measles-specific immunoglobulin M (IgM) in the serum of infected persons. Interpreting a positive IgM result from a person with suspected measles can be difficult if the person has recently received a measles vaccine. We have previously demonstrated that measles-specific IgM may persist for at least 8 weeks after primary vaccination, but it is unknown how quickly IgM appears. This study determined the timing of the rise of measles-specific IgM and IgG after primary measles vaccination with Schwartz vaccine. Two hundred eighty 9-month-old children from Ethiopia presenting for routine measles vaccination were enrolled. Sera were collected before and either 1, 2, 3, or 4 weeks after vaccination and tested for measles-specific antibodies by an IgM capture enzyme immunoassay (EIA) and by an indirect IgG EIA. A total of 209 of the 224 children who returned for the second visit had prevaccination sera that were both IgM and IgG negative. The postvaccination IgM positivity rates for these 209 children were 2% at 1 week, 61% at 2 weeks, 79% at 3 weeks, and 60% at 4 weeks. The postvaccination IgG positivity rates were 0% at 1 week, 14% at 2 weeks, 81% at 3 weeks, and 85% at 4 weeks. We conclude that an IgM-positive result obtained by this antibody capture EIA is difficult to interpret if serum is collected between 8 days and 8 weeks after vaccination; in this situation, the diagnosis of measles should be based on an epidemiologic linkage to a confirmed case or on the detection of wild-type measles virus.

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