scholarly journals Horizontal and Vertical Transmission of Human Immunodeficiency Virus Type 1 Dual Infections Caused by Viruses of Subtypes B and C

1998 ◽  
Vol 177 (1) ◽  
pp. 227-231 ◽  
Author(s):  
Luiz M. Janini ◽  
Amilcar Tanuri ◽  
Mauro Schechter ◽  
Jose M. Peralta ◽  
Ana C. P. Vicente ◽  
...  
2000 ◽  
Vol 4 (3) ◽  
pp. 148-152 ◽  
Author(s):  
Sayomporn Sirinavin ◽  
Winit Phaupradit ◽  
Surasak Taneepanichskul ◽  
Kalayanee Atamasirikul ◽  
Priyasuda Hetrakul ◽  
...  

1994 ◽  
Vol 94 (5) ◽  
pp. 2060-2067 ◽  
Author(s):  
A B van't Wout ◽  
N A Kootstra ◽  
G A Mulder-Kampinga ◽  
N Albrecht-van Lent ◽  
H J Scherpbier ◽  
...  

2008 ◽  
Vol 27 (3) ◽  
pp. 278-280 ◽  
Author(s):  
Mireille Henry ◽  
Isabelle Thuret ◽  
Caroline Solas ◽  
Sèverine Genot ◽  
Philippe Colson ◽  
...  

2021 ◽  
Vol 15 (10) ◽  
pp. 1547-1550
Author(s):  
Dinamene Oliveira ◽  
João Piedade ◽  
Rita Castro ◽  
Ângela Lopes ◽  
Maria do Rosário Martins ◽  
...  

Introduction: Sexually transmitted infections are among the most frequent infections affecting pregnant women. We assessed the transmission of hepatitis B virus, human immunodeficiency virus type 1 and Treponema pallidum to newborns from infected parturients. Methodology: An observational, cross-sectional, analytical facility-based survey was conducted among 57 newborns in Irene Neto Maternity, Lubango city, Huíla province, Angola. Hepatitis B virus DNA molecular identification was done through nested PCR. Human immunodeficiency virus type 1 proviral DNA detection was carried out by two successive nested PCRs. Real-time PCR was performed to examine the presence of T. pallidum DNA. Amplicons from PCR positive samples were sequenced for identity search and genotype assignment. Results: Hepatitis B virus DNA genotype E was detected in 3/41 (7.3%) newborns from HBsAg (hepatitis B surface antigen) positive mothers. To analyse the association between mothers HBeAg (hepatitis B e antigen) positivity and hepatitis B virus vertical transmission to newborns, a Fisher's exact test was performed, showing a highly significant association (p = 0.006). Human immunodeficiency virus type 1 provirus or T. pallidum DNA was not detected in any newborn. Conclusions: To prevent hepatitis B virus vertical transmission in Angola it is important to promote universal antenatal screening, expanding hepatitis B virus markers (viral load and/or HBeAg), risk-based infected mothers’ antiviral therapy and newborn passive immunoprophylaxis.


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