scholarly journals Assessment of Intervention Measures for the 2003 SARS Epidemic in Taiwan by Use of a Back-Projection Method

2007 ◽  
Vol 28 (05) ◽  
pp. 525-530 ◽  
Author(s):  
Paul S. F. Yip ◽  
Y. H. Hsieh ◽  
Ying Xu ◽  
K. F. Lam ◽  
C. C. King ◽  
...  

Objectives. To reconstruct the infection curve for the 2003 severe acute respiratory syndrome (SARS) epidemic in Taiwan and to ascertain the temporal changes in the daily number of infections that occurred during the course of the outbreak. Method. Back-projection method. Results. The peaks of the epidemic correspond well with the occurrence of major infection clusters in the hospitals. The overall downward trend of the infection curve after early May corresponds well to the date (May 10) when changes in the review and classification procedure were implemented by the SARS Prevention and Extrication Committee. Conclusion. The major infection control measures taken by the Taiwanese government over the course of the SARS epidemic, particularly those regarding infection control in hospitals, played a crucial role in containing the outbreak.

Author(s):  
Kathleen Tsoi ◽  
Kate Chan ◽  
Chi Ngong Lawrence Chan ◽  
Geoffrey Mok ◽  
Albert Li ◽  
...  

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection usually causes no or mild coryzal symptoms in the paediatric population. In this letter, we describe a 21-month-old boy infected with SARS-CoV-2 who presented atypically with features compatible with croup. With the current Coronavirus Disease 2019 (COVID-19) pandemic, infection control measures need to be appropriately heightened and early diagnostic sampling for SARS-CoV-2 should be carried out even in symptomatology that is atypical of COVID-19.


2005 ◽  
Vol 18 (1) ◽  
pp. 63-70
Author(s):  
Anjly Sheth ◽  
Frank Romanelli

The severe acute respiratory syndrome (SARS) pandemic depicted the vulnerability of man and tested our ability to respond to a global emergency. The SARS-coronavirus has been postulated to originate in animals and subsequently spread to and infect humans. It is transmissible via direct and indirect contact with infected persons or their environment. Poor infection control practices have been responsible for numerous outbreaks. In the human host, the virus can cause pulmonary sequelae and can result in death. Collaborative international efforts between health care workers and scientists led to the detection and isolation of the virus. Use of available antiviral therapies and implementation of strict infection control measures became pivotal for disease containment, as the discovery for new agents to eradicate the virus emerged. To date, novel preventative or curativemedications and vaccines are lacking. Lessons learned from this pandemic must be remembered, as the emergence of another unknown infectious disease can occur instantaneously and, once again, endanger mankind.


2020 ◽  
Author(s):  
Yuan-Ti Lee ◽  
Shih-Ming Tsao ◽  
Chien-Feng Li ◽  
Ying-Hsiang Chou ◽  
Chien-Ning Huang ◽  
...  

Abstract The emergence of the coronavirus disease 2019 (COVID-19) caused a large-scale outbreak and has rapidly spread across China and multiple countries. We reported countermeasures in infection control for diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) infection and the experiences of point of care diagnostics and medical quarantine for presumed SARS-CoV-2-infected subjects. We conducted a retrospective cohort study on subjects came to Chung Shan Medical University Hospital with suspicion of SARS-CoV-2 infection during January to March, 2020. We performed the real-time reverse-transcription polymerase chain reaction testing (rRT-PCR) for SARS-CoV-2-infection and reported the results of testing and treatment. A total of 212 participants were enrolled due to suspicion of SARS-CoV-2 infection. Five of those were confirmed COVID-19 cases after monitoring for a period of 14 days and were cured. The time to rRT-PCR test conversion after treatment is variate. The infection control measures of home quarantine and mandatory medical quarantine combined with rapid diagnosis seem to postpone the speed of transmission of SARS-CoV-2 infection at once in Taiwan. Due to lack of vaccination and confirmed antiviral therapy, it is important to strictly abide by the infection control measures.


2004 ◽  
Vol 100 (6) ◽  
pp. 1394-1398 ◽  
Author(s):  
Victor Wei Ter Chee ◽  
Mark Li-Chung Khoo ◽  
Sow Fong Lee ◽  
Yeow Choy Lai ◽  
Ngek Mien Chin

Background Singapore reported its first case of Severe Acute Respiratory Syndrome (SARS) in early March 2003 and was placed on the World Health Organization's list of SARS-affected countries on March 15, 2003. During the outbreak, Tan Tock Seng Hospital was designated as the national SARS hospital in Singapore to manage all known SARS patients. Stringent infection control measures were introduced to protect healthcare workers and control intrahospital transmission of SARS. Work-flow processes for surgery were extensively modified. Methods The authors describe the development of infection control measures, the conduct of surgical procedures, and the management of high-risk procedures during the SARS outbreak. Results Forty-one operative procedures, including 15 high-risk procedures (surgical tracheostomy), were performed on SARS-related patients. One hundred twenty-four healthcare workers had direct contact with SARS patients during these procedures. There was no transmission of SARS within the operating room complex. Conclusions Staff personal protection, patient risk categorization, and reorganization of operating room workflow processes formed the key elements for the containment of SARS transmission. Lessons learned during this outbreak will help in the planning and execution of infection control measures, should another outbreak occur.


PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0257513
Author(s):  
Hiroshi Hori ◽  
Takahiko Fukuchi ◽  
Masamitsu Sanui ◽  
Takashi Moriya ◽  
Hitoshi Sugawara

Background Coronavirus disease (COVID-19) is associated with a high mortality rate in older adults; therefore, it is important for medical institutions to take measures to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. This study aimed to assess the risk of SARS-CoV-2 infection among healthcare workers (HCWs) and the effectiveness of infection control measures. Methods This study had a cross-sectional component and a prospective cohort component. The cross-sectional component comprised an anti-SARS-CoV-2 antibody survey among HCWs at a medical center in Saitama City, Japan. In the prospective cohort component, HCWs at the same medical center were tested for anti-SARS-CoV-2 antibodies monthly over a 3-month period (May to July 2020) to assess the effectiveness of infection prevention measures, including personal protective equipment use. All participants in the cohort study also participated in the antibody survey. The primary outcome was anti-SARS-CoV-2 antibody (measured using Elecsys® Anti-SARS-CoV-2) positivity based on whether participants were engaged in COVID-19-related medical care. Other risk factors considered included occupational category, age, and sex. Results In total, 607 HCWs participated in the antibody survey and 116 doctors and nurses participated in the cohort study. Only one of the 607 participants in the survey tested positive for anti-SARS-CoV-2 antibodies. All participants in the cohort study were anti-SARS-CoV-2 antibody negative at baseline and remained antibody negative. Engaging in the care of COVID-19 patients did not increase the risk of antibody positivity. During the study period, a total of 30 COVID-19 in-patients were treated in the hospital. Conclusions The infection control measures in the hospital protected HCWs from nosocomially acquired SARS-CoV-2 infection; thus, HCWs should engage in COVID-19-related medical care with confidence provided that they adhere to infectious disease precautions.


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