scholarly journals A Prospective Nationwide Study of Clostridium difficile‐Associated Diarrhea in Sweden

1998 ◽  
Vol 26 (1) ◽  
pp. 141-145 ◽  
Author(s):  
Olle Karlström ◽  
Birgitta Fryklund ◽  
Kjell Tullus ◽  
Lars G. Burman ◽  
Keyword(s):  
Clostridium Difficile ◽  
Nationwide Study ◽  
Clostridium Difficile Associated Diarrhea

Risk Factors for Recurrence of Clostridium Difficile-associated Diarrhea in the Elderly

2002 ◽  
Vol 34 (8) ◽  
pp. 594-597 ◽  
Author(s):  
Sari Tal ◽  
Alexander Gurevich ◽  
Vladimir Guller ◽  
Irina Gurevich ◽  
David Berger ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
The Elderly ◽  
Risk Factors For Recurrence ◽  
Clostridium Difficile Associated Diarrhea

Clostridium difficile—Associated Diarrhea, an Emerging Epidemic: Therapeutic Options

2007 ◽  
Vol 20 (4) ◽  
pp. 347-353
Author(s):  
Christopher R. Emerson
Keyword(s):  
Clostridium Difficile ◽  
Hospital Admissions ◽  
Treatment Options ◽  
Infectious Diarrhea ◽  
First Line ◽  
Oral Vancomycin ◽  
Considerable Morbidity ◽  
Clostridium Difficile Associated Diarrhea ◽  
Pharmacologic Agents ◽  
Oral Metronidazole

Clostridum difficile—associated disease (CDAD) is the leading cause of infectious diarrhea and is associated with considerable morbidity and mortality. The incidence is estimated to range from 3.4 to 8.4 cases per 1000 hospital admissions, and it has become a growing problem at many institutions. Treatment options for CDAD are limited due to a paucity of new pharmacologic agents and studies examining other potential treatments. Historically oral metronidazole and oral vancomycin have been used as first-line agents in the treating CDAD, however recent reports of treatment failure and recurrence with these agents have surfaced. These reports illustrate a need for novel pharmacologic agents and a thorough review of currently available agents that may have activity against C difficile. Available data on the treatment of CDAD were extracted and reviewed to outline the appropriate management of CDAD.

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