scholarly journals Intravenous Immunoglobulin Therapy for Streptococcal Toxic Shock Syndrome—A Comparative Observational Study

1999 ◽  
Vol 28 (4) ◽  
pp. 800-807 ◽  
Author(s):  
Rupert Kaul ◽  
Allison McGeer ◽  
Anna Norrby‐Teglund ◽  
Malak Kotb ◽  
Benjamin Schwartz ◽  
...  
Keyword(s):  
Observational Study ◽  
Intravenous Immunoglobulin ◽  
Toxic Shock Syndrome ◽  
Immunoglobulin Therapy ◽  
Streptococcal Toxic Shock Syndrome ◽  
Toxic Shock ◽  
Intravenous Immunoglobulin Therapy

Early intravenous immunoglobulin therapy for group A β-haemolytic streptococcal meningitis with toxic shock syndrome

2021 ◽  
Vol 14 (3) ◽  
pp. e238472
Author(s):  
Derick Adigbli ◽  
Valerie Rozen ◽  
Archie Darbar ◽  
Pierre Janin
Keyword(s):  
Supportive Care ◽  
Intravenous Immunoglobulin ◽  
Toxic Shock Syndrome ◽  
Immunoglobulin Therapy ◽  
High Dose ◽  
Streptococcal Toxic Shock Syndrome ◽  
Full Time ◽  
Toxic Shock ◽  
Intravenous Immunoglobulin Therapy ◽  
Group A

A woman in her forties was transferred to a Sydney (Australia)-based tertiary hospital, following presentation to a regional hospital with group A Streptococcus (GAS) otomastoiditis; complicated by meningitis, venous sinus thrombosis, haemorrhagic cerebral infarction and subdural empyema. She rapidly deteriorated with profound cardiovascular collapse. Despite initiation of high dose vasoactive therapy, she remained shocked and developed multiorgan dysfunction syndrome. Early intravenous immunoglobulin therapy (140 g in two doses) was initiated as an adjunct to antimicrobial, surgical and supportive care for refractory streptococcal toxic shock syndrome. Over the course of a twelve-day intensive care unit stay she made good progress with de-escalation of her vasoactive supportive care and reversal of her organ injuries. She was subsequently discharged to ward-based care. At her three-month follow-up appointment she had significantly reduced neurological deficit. Five months following her presentation to hospital she had returned to full-time work.

Adjunctive Treatment of Streptococcal Toxic Shock Syndrome Using Intravenous Immunoglobulin: Case Report and Review

1997 ◽  
Vol 102 (1) ◽  
pp. 111-112 ◽  
Author(s):  
Carlos M Perez ◽  
Bernard M Kubak ◽  
Henry G Cryer ◽  
Saleh Salehmugodam ◽  
Paul Vespa ◽  
...  
Keyword(s):  
Case Report ◽  
Intravenous Immunoglobulin ◽  
Toxic Shock Syndrome ◽  
Adjunctive Treatment ◽  
Streptococcal Toxic Shock Syndrome ◽  
Toxic Shock
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