scholarly journals Congenital Tuberculosis in a Neonatal Intensive Care Unit: Case Report, Epidemiological Investigation, and Management of Exposures

1998 ◽  
Vol 27 (3) ◽  
pp. 474-477 ◽  
Author(s):  
L. H. Lee ◽  
C. M. LeVea ◽  
P. S. Graman
2002 ◽  
Vol 23 (10) ◽  
pp. 573-579 ◽  
Author(s):  
Brent W. Laartz ◽  
Hugo J. Narvarte ◽  
Douglas Holt ◽  
Julie A. Larkin ◽  
William F. Pomputius

Objective:We report a case of congenital tuberculosis in a neonatal intensive care unit (NICU) and the management of exposure to other neonates in the hospital. We review the literature regarding congenital tuberculosis and management of exposures in the NICU.Design:Case report and a survey of exposures with a 3-month follow-up.Setting:Urban hospital.Patients:Neonates exposed to a case of congenital tuberculosis.Interventions:Exposure to tuberculosis was treated with isoniazid. Purified protein derivative tests were placed at base-line and 3 to 4 months after exposure. Chest radiographs were performed if clinically indicated.Results:Congenital tuberculosis was diagnosed in our patient at 21 days of age during a prolonged hospital course. After initiation of anti-tuberculous medications, the patient gradually recovered from his illness. While he was treated in the NICU, there were 37 potentially exposed infants. Of these, 36 were administered tuberculin skin tests (average age, 1.7 months), all of which were read as 0 mm of induration. Of those 37, 35 began prophylaxis with isoniazid, and 30 were able to complete treatment with a minimum of 3 months of isoniazid therapy. Of those 30, two infants received 6 months of therapy. Additionally, 29 of the 37 infants had chest radiographs, none of which showed suspicious infiltrates or adenopathy. Finally, 30 of the 36 infants had repeat tuberculin skin tests at 3 months, all of which were read as 0 mm of induration (average age, 3.7 months).Conclusion:Congenital tuberculosis is an uncommon disease that requires early diagnosis for successful therapy and vigilant follow-up of potential exposures in the NICU. (Infect Control Hosp Epidemiol 2002;23:573-579).


1988 ◽  
Vol 16 (4) ◽  
pp. 167-172 ◽  
Author(s):  
Beth Hewitt Stover ◽  
Karen M. Cost ◽  
Charles Hamm ◽  
Garrett Adams ◽  
Larry N. Cook

Author(s):  
Ibrahim A. Abdelazim ◽  
Sulaiman Al-Munaifi

<p>The incidence of multiple gestations increased after introduction of assisted reproduction techniques. Traditionally; in twin and/or triplet pregnancies; if one baby delivered preterm, this situation managed by delivery of the second and/or the third fetuses. This case report represents the suggested conservative management during the delayed delivery of the two remaining fetuses of triplet pregnancy, its outcome, and benefits.<br />The studied woman is 35-years old, G3 P2, triplet pregnancy after intra-cytoplasmic sperm injection trial, presented with preterm premature rupture of membranes of the first fetus at 20+2 weeks` gestation, who delivered as fresh still birth. The couple informed, and agreed for the conservative management of the two remaining fetuses. After delivery of the first fetus; the umbilical cord ligated as high as possible in the cervix. She received systemic antibiotics for one week, with follow up of; infections, and consumptive coagulopathy parameters, and wellbeing of the fetuses through the conservative treatment. She received betamethasone to accelerate the lung maturity, and Mg-Sulphate for fetal neuro-protection at 24 weeks. The conservative management discontinued, and she delivered by cesarean section at 25 weeks+1 after attack of ante-partum hemorrhage. The delivered neonates admitted to neonatal intensive care unit on ventilator support, surfactant therapy, and antibiotics. 80 days after neonatal intensive care unit admission; the neonates discharged from the neonatal intensive care unit with corrected age of 36 weeks+, on complete oral feeding, and room air. <br />The first fetus delivered at 20 weeks+2, fresh still birth (410 g), while the second, and third fetuses delivered at 25 weeks+1 (34 days of the conservative management), 780, and 840 g; respectively. Both fetuses survived, discharged from the neonatal intensive care unit after 80 days, at 2.2, and 2.3 kg weight; respectively. <br />The birth weight, and the survival rate of both fetuses increased after the conservative management. The suggested conservative management of the delayed delivery may be associated with reduced neonatal mortalities without any maternal complications.</p>


2004 ◽  
Vol 39 (11) ◽  
pp. 1719-1723 ◽  
Author(s):  
Maryanne Crockett ◽  
Susan M. King ◽  
Ian Kitai ◽  
Frances Jamieson ◽  
Susan Richardson ◽  
...  

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