scholarly journals Multipoint Linkage-Disequilibrium Mapping with Haplotype-Block Structure

2007 ◽  
Vol 80 (1) ◽  
pp. 112-125 ◽  
Author(s):  
Maoxia Zheng ◽  
Mary Sara McPeek
Keyword(s):  
Linkage Disequilibrium ◽  
Haplotype Block ◽  
Block Structure ◽  
Linkage Disequilibrium Mapping ◽  
Multipoint Linkage ◽  
Haplotype Block Structure

scholarly journals Evaluation of Linkage Disequilibrium, Effective Population Size and Haplotype Block Structure in Chinese Cattle

Animals ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 83 ◽  
Author(s):  
Lei Xu ◽  
Bo Zhu ◽  
Zezhao Wang ◽  
Ling Xu ◽  
Ying Liu ◽  
...  
Keyword(s):  
Linkage Disequilibrium ◽  
Genomic Selection ◽  
Haplotype Block ◽  
Block Structure ◽  
Effective Population ◽  
Chinese Cattle ◽  
Genome Wide ◽  
Population Sizes ◽  
Haplotype Block Structure ◽  
Selection For

Understanding the linkage disequilibrium (LD) across the genome, haplotype structure, and persistence of phase between breeds can enable us to appropriately design and implement the genome-wide association (GWAS) and genomic selection (GS) in beef cattle. We estimated the extent of genome-wide LD, haplotype block structure, and the persistence of phase in 10 Chinese cattle population using high density BovinHD BeadChip. The overall LD measured by r2 between adjacent SNPs were 0.60, 0.67, 0.58, 0.73, and 0.71 for South Chinese cattle (SCHC), North Chinese cattle (NCC), Southwest Chinese cattle (SWC), Simmental (SIM), and Wagyu (WAG). The highest correlation (0.53) for persistence of phase across groups was observed for SCHC vs. SWC at distances of 0–50 kb, while the lowest correlation was 0.13 for SIM vs. SCHC at the same distances. In addition, the estimated current effective population sizes were 27, 14, 31, 34, and 43 for SCHC, NCC, SWC, SIM, and WAG, respectively. Our result showed that 58K, 87K, 95K, 52K, and 52K markers were required for implementation of GWAS and GS in SCHC, NCC, SWC, SIM, and WAG, respectively. Also, our findings suggested that the implication of genomic selection for multipopulation with high persistence of phase is feasible for Chinese cattle.

scholarly journals Linkage disequilibrium and haplotype block structure in a composite beef cattle breed

BMC Genomics ◽  
2014 ◽  
Vol 15 (Suppl 7) ◽  
pp. S6 ◽  
Author(s):  
Fabiana Mokry ◽  
Marcos Buzanskas ◽  
Maurício de Alvarenga Mudadu ◽  
Daniela do Amaral Grossi ◽  
Roberto Higa ◽  
...  
Keyword(s):  
Linkage Disequilibrium ◽  
Beef Cattle ◽  
Haplotype Block ◽  
Block Structure ◽  
Cattle Breed ◽  
Haplotype Block Structure

Linkage disequilibrium and haplotype block structure in Limousin, Simmental and native Polish Red cattle

2016 ◽  
Vol 191 ◽  
pp. 57-63 ◽  
Author(s):  
I. Jasielczuk ◽  
A. Gurgul ◽  
T. Szmatoła ◽  
T. Ząbek ◽  
K. Pawlina ◽  
...  
Keyword(s):  
Linkage Disequilibrium ◽  
Haplotype Block ◽  
Block Structure ◽  
Haplotype Block Structure

scholarly journals Linkage Disequilibrium Decay and Haplotype Block Structure in the Pig

Genetics ◽  
2008 ◽  
Vol 179 (1) ◽  
pp. 569-579 ◽  
Author(s):  
Andreia J. Amaral ◽  
Hendrik-Jan Megens ◽  
Richard P. M. A. Crooijmans ◽  
Henri C. M. Heuven ◽  
Martien A. M. Groenen
Keyword(s):  
Linkage Disequilibrium ◽  
Haplotype Block ◽  
Block Structure ◽  
Linkage Disequilibrium Decay ◽  
Haplotype Block Structure

scholarly journals Linkage disequilibrium and haplotype block structure in six commercial pig lines

2013 ◽  
Vol 91 (8) ◽  
pp. 3493-3501 ◽  
Author(s):  
R. Veroneze ◽  
P. S. Lopes ◽  
S. E. F. Guimarães ◽  
F. F. Silva ◽  
M. S. Lopes ◽  
...  
Keyword(s):  
Linkage Disequilibrium ◽  
Haplotype Block ◽  
Block Structure ◽  
Haplotype Block Structure

scholarly journals Erratum: Significant variation in haplotype block structure but conservation in tagSNP patterns among global populations

2007 ◽  
Vol 15 (7) ◽  
pp. 818-818 ◽  
Author(s):  
Sheng Gu ◽  
Andrew J Pakstis ◽  
Hui Li ◽  
William C Speed ◽  
Judith R Kidd ◽  
...  
Keyword(s):  
Significant Variation ◽  
Haplotype Block ◽  
Block Structure ◽  
Haplotype Block Structure
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