scholarly journals The Influence of High‐Efficiency Particulate Air Filtration on Mortality and Fungal Infection among Highly Immunosuppressed Patients: A Systematic Review

2006 ◽  
Vol 193 (10) ◽  
pp. 1408-1419 ◽  
Author(s):  
Tim Eckmanns ◽  
Henning Rüden ◽  
Petra Gastmeier
Energies ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3530
Author(s):  
Fukang Ma ◽  
Shuanlu Zhang ◽  
Zhenfeng Zhao ◽  
Yifang Wang

The hydraulic free-piston engine (HFPE) is a kind of hybrid-powered machine which combines the reciprocating piston-type internal combustion engine and the plunger pump as a whole. In recent years, the HFPE has been investigated by a number of research groups worldwide due to its potential advantages of high efficiency, energy savings, reduced emissions and multi-fuel operation. Therefore, our study aimed to assess the operating characteristics, core questions and research progress of HFPEs via a systematic review and meta-analysis. We included operational control, starting characteristics, misfire characteristics, in-cylinder working processes and operating stability. We conducted the literature search using electronic databases. The research on HFPEs has mainly concentrated on four kinds of free-piston engine, according to piston arrangement form: single piston, dual pistons, opposed pistons and four-cylinder complex configuration. HFPE research in China is mainly conducted in Zhejiang University, Tianjin University, Jilin University and the Beijing Institute of Technology. In addition, in China, research has mainly focused on the in-cylinder combustion process while a piston is free by considering in-cylinder combustion machinery and piston dynamics. Regarding future research, it is very important that we solve the instabilities brought about by chance fluctuations in the combustion process, which will involve the hydraulic system’s efficiency, the cyclical variation, the method of predicting instability and the recovery after instability.


BDJ Open ◽  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Nashib Pandey ◽  
Buddha Bahadur Basnet ◽  
Sushmit Koju ◽  
Anju Khapung ◽  
Alka Gupta

Abstract Objective To access the awareness of dental practitioners of Nepal towards COVID-19 transmission through aerosols. Materials and methods The study involved 384 dentists from all over Nepal and was conducted for a period of 3 months. A self-reported online questionnaire was developed using Google forms and the link was shared. It emphasized the awareness related to the aerosol and ventilation system in their daily practices was prepared. The data were analyzed in Statistical Package for Social Sciences version 20.0 software. Results The majority of participants were female 52.9% (n = 203) and within the age groups of <30 years 57% (n = 219). Participants from Bagmati Province were 60.4% (n = 232), with least from Sudurpaschim Province 0.5% (n = 2). 60% of participants provided only emergency services during the COVID-19 pandemic and few (7%) provided consultations via telephone. The current ventilation system used was a well-ventilated room with open windows 65.4% (n = 251). However, 52.8% (n = 203) preferred specialized operatory incorporating high-efficiency particulate air (HEPA) filters and ultraviolet (UV) light. More than 60% of respondents were unaware of the particle size of the aerosol. Conclusions The obtained results signify the need for the proper ventilation system with appropriate air filtration systems in dental clinical setups.


2021 ◽  
pp. 014556132110141
Author(s):  
Marios Stavrakas ◽  
Ioannis Koskinas ◽  
Jannis Constantinidis ◽  
Petros D Karkos

Mucormycosis is a type of fungal infection more prevalent among immunosuppressed patients, requires prompt identification and surgical treatment, as it can is associated with local and distant spread. This case is aiming to highlight the importance of early identification of subtle symptoms in immunocompromised patients. The clinician should be aware of fungal sinusitis, consider it in the differential diagnosis, and seek for an ear, nose, and throat opinion.


Author(s):  
Carlo Lajolo ◽  
Rupe Cosimo ◽  
Schiavelli Anna ◽  
Gioco Gioele ◽  
Metafuni Elisabetta ◽  
...  

Background: Saprochaete clavata infection is an emerging issue in immunosuppressed patients, causing fulminant fungaemia. The purpose of this systematic review of cases is to retrieve all cases of S. clavata infection and describe oral lesions as the first manifestation of S. clavata infection. Methods: We report the first case of intraoral S. clavata infection in Acute Myeloid Leukemia (AML) affected subject, presenting as multiple grayish rapidly growing ulcerated swellings, and provide a review of all published cases of infection caused by S. clavata, according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, conducted by searching SCOPUS, Medline, and CENTRAL databases. Only articles in English were considered. Individual patient data were analyzed to identify risk factors for S. clavata infection. Results: Seventeen of 68 retrieved articles were included in the review reporting data on 96 patients (mean age 51.8 years, 57 males and 38 females). Most cases were disseminated (86) with a 60.2% mortality rate. Ninety-five were hematological patients, with AML being the most common (57 cases). Conclusions:S. clavata infection in immunosuppressed patients has a poor prognosis: middle-age patients, male gender and Acute Myeloid Leukemia should be considered risk factors. In immunosuppressed patients, the clinical presentation can be particularly unusual, imposing difficult differential diagnosis, as in the reported case.


2021 ◽  
Vol 32 (24) ◽  
pp. 245707
Author(s):  
Jiaxin Jiang ◽  
Zungui Shao ◽  
Xiang Wang ◽  
Ping Zhu ◽  
Shiqing Deng ◽  
...  

2009 ◽  
Vol 46 (4) ◽  
pp. 22-25 ◽  
Author(s):  
Ned Galka ◽  
Abhishek Saxena

2017 ◽  
Vol 138 ◽  
pp. 124-133 ◽  
Author(s):  
Xiaobing Liu ◽  
Hamid Souzandeh ◽  
Yudong Zheng ◽  
Yajie Xie ◽  
Wei-Hong Zhong ◽  
...  

Author(s):  
Christopher A. Perullo ◽  
Josh Barron ◽  
Dale Grace ◽  
Leonard Angello ◽  
Tim Lieuwen

Gas turbines ingest large quantities of air during operation. As a result, large quantities of foreign particles ranging in size from smoke (0.01 to 1.0 micron) to pollen (10 micron) enter the unit and can contribute to both fouling and erosion depending on particle size. Fouling and erosion both lead to reductions in unit output and efficiency resulting in increased operational cost. Operators have historically combatted fouling through a combination of online water washes, more effective off-line water washes, and air filtration. As is the case with almost all engineering problems, the trade-off between the cost and effectiveness of these methods must be evaluated. Online washing is somewhat effective but has led to first stage blade erosion and unit trips in some cases. Off-line washing is more effective at cleaning the unit, but requires the unit to be shut down for extended periods of time. Air filtration can help prevent foreign particles from entering the unit, but higher efficiency filters are generally associated with a larger inlet pressure drop, leading to decreased unit output; this is balanced against reduced fouling rates. These tradeoffs between the costs associated with higher efficiency filters and the frequency of compressor washing need to be evaluated on a plant-by-plant basis to determine the best combination of air filtration and compressor washing programs. This paper presents a field study carried out to determine the effectiveness of high efficiency filters in preventing compressor fouling. Fourteen units at four sites were monitored over a 9 month to 3 year time period to determine the changes in unit performance and the impact of water washes on unit performance for both pre and final filters of lower and higher efficiency ratings. Results to date indicate that higher efficiency filters are effective at reducing the need for off-line water washes and potentially reduce life-cycle cost. Reduced output from the higher pressure drop, high efficiency filters is offset by the better performance retention offered from reduced fouling rates.


Medicina ◽  
2007 ◽  
Vol 43 (4) ◽  
pp. 278 ◽  
Author(s):  
Arūnė Wallin ◽  
Živilė Lukšienė ◽  
Kęstutis Žagminas ◽  
Genė Šurkienė

Bioterrorism is one of the main public health categorical domains. According to sociological analytics, in postmodern society terrorism is one of the real threats of the 21st century. While rare, the use of biological weapons has a long history. Recently, anthrax has been evaluated as one of the most dangerous biological weapons. Naturally occurring anthrax in humans is a disease acquired from contact with anthrax-infected animals or anthrax-contaminated animal products. Usually anthrax infection occurs in humans by three major routes: inhalational, cutaneous, and gastrointestinal. Inhalational anthrax is expected to account for most serious morbidity and most mortality. The clinical presentation of inhalation anthrax has been described as a two-stage illness. Many factors contribute to the pathogenesis of Bacillus anthracis. Antibiotics, anthrax globulin, corticosteroids, mechanical ventilation, vaccine are possible tools of therapy. Smallpox existed in two forms: variola major, which accounted for most morbidity and mortality, and a milder form, variola minor. Smallpox spreads from person to person primarily by droplet nuclei or aerosols expelled from the oropharynx of infected persons and by direct contact. In the event of limited outbreak with few cases, patients should be admitted to the hospital and confined to rooms that are under negative pressure and equipped with high-efficiency particulate air filtration. In larger outbreaks, home isolation and care should be the objective for most patients. Progress in detection, suitable vaccines, postexposure prophylaxis, infection control, and decontamination might be serious tools in fight against the most powerful biological weapon. To assure that the public health and healthcare system can respond to emergencies, the government should direct resources to strengthen the emergency-response system, create medication stockpiles, and improve the public health infrastructure.


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