Bacteremia Due to Persistent Strains of Coagulase-Negative Staphylococci in a Neonatal Intensive-Care Unit

1999 ◽  
Vol 20 (05) ◽  
pp. 349-351 ◽  
Author(s):  
Lillian Sung ◽  
Karam Ramotar ◽  
Lindy M. Samson ◽  
Baldwin Toye
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Case Control Study ◽  
Case Control ◽  
Retrospective Case ◽  
Coagulase Negative Staphylococci ◽  
Control Study

AbstractThis retrospective case-control study was performed to determine risk factors for bacteremia due to persistent coagulase-negative staphylococci in our neonatal intensive-care unit. Enteral nutrition and the presence of a nasogastric tube were identified as possible risk factors for coagulase-negative staphylococcal bacteremia involving one of the persistent strains.

scholarly journals 1176 RISK FACTORS FOR CANDIDEMIA IN THE NEONATAL INTENSIVE CARE UNIT (NICU): A CASE-CONTROL STUDY

1985 ◽  
Vol 19 (4) ◽  
pp. 306A-306A
Author(s):  
Debra E Weese-Mayer ◽  
Diane Wheeler Fondriest ◽  
Robert T Brouillette ◽  
Stanford T Shulman
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals RISK FACTORS FOR CANDIDEMIA IN A NEONATAL INTENSIVE CARE UNIT: A CASE-CONTROL STUDY 1328

1997 ◽  
Vol 41 ◽  
pp. 224-224
Author(s):  
Luís Eduardo Vaz Miranda ◽  
Márcio Nucci ◽  
Samura Maura Barreto E Silva ◽  
Lúcia de Fátima Guimarães ◽  
Simone Xavier
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Clustering ofSerratia marcescensInfections in a Neonatal Intensive Care Unit

2004 ◽  
Vol 25 (9) ◽  
pp. 723-729 ◽  
Author(s):  
Emmi Sarvikivi ◽  
Outi Lyytikäinen ◽  
Saara Salmenlinna ◽  
Jaana Vuopio-Varkila ◽  
Päivi Luukkainen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Case Control Study ◽  
Tertiary Care ◽  
Case Control ◽  
Pfge Analysis ◽  
Control Study

AbstractObjectives:To study clusters of infections caused bySerratia marcescensin a neonatal intensive care unit (NICU) and to determine risk factors forS. marcescensinfection or colonization.Design:Genotyping ofS. marcescensisolates was performed by pulsed-field gel electrophoresis (PFGE). A retrospective case-control study was conducted.Setting:A tertiary-care pediatric hospital with a 16-bed NICU.Patients:All neonates with at least one culture positive forS. marcescensin the NICU during December 1999 to July 2002. Case-patients (n = 11) treated in the NICU during December 1999 to February 2000 were included in the case-control study. Neonates treated in the NICU for at least 72 hours during the same period with cultures negative forS. marcescenswere used as control-patients (n = 27).Results:S. marcescenswas cultured from 19 neonates; 9 were infected and 10 were colonized. PFGE analysis identified three epidemic strains; each cluster consisted of identical isolates, except one isolate in the first cluster that was different. The risk factors identified were low birth weight, prematurity, prolonged respiratory therapy, prolonged use of antibiotics, and maternal infection prior to delivery. Overcrowding and understaffing were recorded simultaneously with the clusters.Conclusions:PFGE analysis showed three independent clusters. Several factors contributed to spread of the epidemic strains: (1) there were many severely premature and susceptible neonates, (2) the NICU was overcrowded during the clusters, and (3) transmission was likely to occur via the hands of staff. Cohorting and improvement of routine infection control measures led to the cessation of each cluster.

Vancomycin-resistant Enterococcus (VRE) outbreak in a neonatal intensive care unit and special care nursery at a tertiary-care hospital in Australia—A retrospective case-control study

2019 ◽  
Vol 40 (05) ◽  
pp. 551-558 ◽  
Author(s):  
Patiyan Andersson ◽  
Wendy Beckingham ◽  
Claire Louise Gorrie ◽  
Karina Kennedy ◽  
Kathryn Daveson ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Case Control Study ◽  
Tertiary Care ◽  
Case Control ◽  
Retrospective Case ◽  
Vancomycin Resistant ◽  
Control Study

AbstractObjective:We investigated the risk factors and origins of the first known occurrence of VRE colonization in the neonatal intensive care unit (NICU) at the Canberra Hospital.Design:A retrospective case-control study.Setting:A 21-bed neonatal intensive care unit (NICU) and a 15-bed special care nursey (SCN) in a tertiary-care adult and pediatric hospital in Australia.Patients:All patients admitted to the NICU and SCN over the outbreak period: January–May 2017. Of these, 14 were colonized with vancomycin-resistant Enterococcus (VRE) and 77 were noncolonized.Methods:Demographic and clinical variables of cases and controls were compared to evaluate potential risk factors for VRE colonization. Whole-genome sequencing of the VRE isolates was used to determine the origin of the outbreak strain.Results:Swift implementation of wide-ranging infection control measures brought the outbreak under control. Multivariate logistic regression revealed a strong association between early gestational age and VRE colonization (odds ratio [OR], 3.68; 95% confidence interval [CI], 1.94–7.00). Whole-genome sequencing showed the isolates to be highly clonal Enterococcus faecium ST1421 harboring a vanA gene and to be closely related to other ST1421 previously sequenced from the Canberra Hospital and the Australian Capital Territory.Conclusion:The colonization of NICU patients was with a highly successful clone endemic to the Canberra Hospital likely introduced into the NICU environment from other wards, with subsequent cross-contamination spreading among the neonate patients. Use of routine surveillance screening may have identified colonization at an earlier stage and have now been implemented on a 6-monthly schedule.

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