scholarly journals Higher Frequency of HIV‐1–Specific T Cell Immune Responses in African American Children Vertically Infected with HIV‐1

2005 ◽  
Vol 192 (10) ◽  
pp. 1772-1780 ◽  
Author(s):  
Elizabeth R. Sharp ◽  
Jason D. Barbour ◽  
R. Karl Karlsson ◽  
Kimberly A. Jordan ◽  
Johan K. Sandberg ◽  
...  
Keyword(s):  
African American ◽  
T Cell ◽  
Immune Responses ◽  
African American Children ◽  
T Cell Immune Responses ◽  
American Children ◽  
Hiv 1

scholarly journals P16-44. Investigating T cell immune responses in Cameroon, a country with broad HIV-1 genetic diversity

Retrovirology ◽  
2009 ◽  
Vol 6 (S3) ◽  
Author(s):  
M Tongo ◽  
E Ebong ◽  
L Zembe ◽  
E Mpoudi Ngole ◽  
W Burgers
Keyword(s):  
Genetic Diversity ◽  
T Cell ◽  
Immune Responses ◽  
T Cell Immune Responses ◽  
Hiv 1

scholarly journals Heterologous Combination of VSV-GP and NYVAC Vectors Expressing HIV-1 Trimeric gp145 Env as Vaccination Strategy to Induce Balanced B and T Cell Immune Responses

2019 ◽  
Vol 10 ◽  
Author(s):  
Beatriz Perdiguero ◽  
Carmen Elena Gómez ◽  
Juan García-Arriaza ◽  
Cristina Sánchez-Corzo ◽  
Carlos Óscar S. Sorzano ◽  
...  
Keyword(s):  
T Cell ◽  
Immune Responses ◽  
Vaccination Strategy ◽  
T Cell Immune Responses ◽  
Hiv 1

scholarly journals Priming with Recombinant BCG Expressing HTI Enhances the Magnitude and Breadth of the T-Cell Immune Responses Elicited by MVA.HTI in BALB/c Mice

Vaccines ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 678
Author(s):  
Narcís Saubi ◽  
Athina Kilpeläinen ◽  
Yoshiki Eto ◽  
Chun-Wei Chen ◽  
Àlex Olvera ◽  
...  
Keyword(s):  
T Cell ◽  
Immune Responses ◽  
T Cell Responses ◽  
Vaccine Platform ◽  
Cell Responses ◽  
Total Magnitude ◽  
T Cell Immune Responses ◽  
Ifn Γ ◽  
Hiv 1 ◽  
Recombinant Bcg

The use of Mycobacterium bovis bacillus Calmette–Guérin (BCG) as a live vaccine vehicle is a promising approach for HIV-1-specific T-cell induction. In this study, we used recombinant BCG expressing HIVACAT T-cell immunogen (HTI), BCG.HTI2auxo.int. BALB/c mice immunization with BCG.HTI2auxo.int prime and MVA.HTI boost was safe and induced HIV-1-specific T-cell responses. Two weeks after boost, T-cell responses were assessed by IFN-γ ELISpot. The highest total magnitude of IFN-γ spot-forming cells (SFC)/106 splenocytes was observed in BCG.HTI2auxo.int primed mice compared to mice receiving MVA.HTI alone or mice primed with BCGwt, although the differences between the vaccination regimens only reached trends. In order to evaluate the differences in the breadth of the T-cell immune responses, we examined the number of reactive peptide pools per mouse. Interestingly, both BCG.HTI2auxo.int and BCGwt primed mice recognized an average of four peptide pools per mouse. However, the variation was higher in BCG.HTI2auxo.int primed mice with one mouse recognizing 11 peptide pools and three mice recognizing few or no peptide pools. The recognition profile appeared to be more spread out for BCG.HTI2auxo.int primed mice and mice only receiving MVA.HTI. Here, we describe a useful vaccine platform for priming protective responses against HIV-1/TB and other prevalent infectious diseases.

scholarly journals Effect ofSchistosoma mansoniInfection on Innate and HIV-1-Specific T-Cell Immune Responses in HIV-1-Infected Ugandan Fisher Folk

2016 ◽  
Vol 32 (7) ◽  
pp. 668-675 ◽  
Author(s):  
Andrew Ekii Obuku ◽  
Gershim Asiki ◽  
Andrew Abaasa ◽  
Isaac Ssonko ◽  
Alexandre Harari ◽  
...  
Keyword(s):  
T Cell ◽  
Immune Responses ◽  
T Cell Immune Responses ◽  
Hiv 1

scholarly journals Cross‐Reactivity of Anti–HIV‐1 T Cell Immune Responses among the Major HIV‐1 Clades in HIV‐1–Positive Individuals from 4 Continents

2005 ◽  
Vol 191 (9) ◽  
pp. 1427-1434 ◽  
Author(s):  
Paul M. Coplan ◽  
Swati B. Gupta ◽  
Sheri A. Dubey ◽  
Punnee Pitisuttithum ◽  
Alex Nikas ◽  
...  
Keyword(s):  
T Cell ◽  
Immune Responses ◽  
Cross Reactivity ◽  
T Cell Immune Responses ◽  
Anti Hiv ◽  
Hiv 1

A new antigen scanning strategy for monitoring HIV-1 specific T-cell immune responses

2012 ◽  
Vol 375 (1-2) ◽  
pp. 46-56 ◽  
Author(s):  
Mauro S. Malnati ◽  
Silvia Heltai ◽  
Antonio Cosma ◽  
Peter Reitmeir ◽  
Simone Allgayer ◽  
...  
Keyword(s):  
T Cell ◽  
Immune Responses ◽  
Scanning Strategy ◽  
T Cell Immune Responses ◽  
Hiv 1

scholarly journals T-Cell Immune Responses Against Env from CRF12_BF and Subtype B HIV-1 Show High Clade-Specificity that Can Be Overridden by Multiclade Immunizations

PLoS ONE ◽  
2011 ◽  
Vol 6 (2) ◽  
pp. e17185 ◽  
Author(s):  
Daniela C. Mónaco ◽  
Ana M. Rodríguez ◽  
María F. Pascutti ◽  
Mauricio Carobene ◽  
Juliana Falivene ◽  
...  
Keyword(s):  
T Cell ◽  
Immune Responses ◽  
Subtype B ◽  
T Cell Immune Responses ◽  
Hiv 1

T cell immune responses to HIV-1

10.2741/2235 ◽  
2007 ◽  
Vol 12 (1) ◽  
pp. 2330 ◽  
Author(s):  
Sandhya Vasan
Keyword(s):  
T Cell ◽  
Immune Responses ◽  
T Cell Immune Responses ◽  
Hiv 1

scholarly journals Assessment of T cell immune responses towards HIV-1 epitopes designed by reverse immunogenetic approach: proof-of-concept in HIV+ Cameroonian children

Retrovirology ◽  
2012 ◽  
Vol 9 (S2) ◽  
Author(s):  
E Nemes ◽  
M Amicosante ◽  
F Ateba Ndongo ◽  
N Fainguem ◽  
S Moyo Tetang ◽  
...  
Keyword(s):  
T Cell ◽  
Immune Responses ◽  
Proof Of Concept ◽  
T Cell Immune Responses ◽  
Hiv 1

Detection of HIV-1-specific T-cell immune responses in highly HIV-exposed uninfected individuals by in-vitro dendritic cell co-culture

AIDS ◽  
2015 ◽  
Vol 29 (11) ◽  
pp. 1309-1318 ◽  
Author(s):  
Alberto C. Guardo ◽  
Marta Ruiz-Riol ◽  
Emma Fernández ◽  
Maria J. Maleno ◽  
Manel E. Bargalló ◽  
...  
Keyword(s):  
T Cell ◽  
Dendritic Cell ◽  
Immune Responses ◽  
T Cell Immune Responses ◽  
Hiv Exposed ◽  
Exposed Uninfected ◽  
Hiv 1
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