Acid‐Base Regulation in the South American LungfishLepidosiren paradoxa: Effects of Prolonged Hypercarbia on Blood Gases and Pulmonary Ventilation

2005 ◽  
Vol 78 (6) ◽  
pp. 908-915 ◽  
Author(s):  
A. P. Sanchez ◽  
H. Giusti ◽  
M. Bassi ◽  
M. L. Glass
2007 ◽  
Vol 155 (1) ◽  
pp. 35-40 ◽  
Author(s):  
J. Amin-Naves ◽  
H. Giusti ◽  
A. Hoffmann ◽  
M.L. Glass
Keyword(s):  

2016 ◽  
pp. 243-254
Author(s):  
Jalile Amin-Naves ◽  
A.P. Sanchez ◽  
M. Bassi ◽  
H. Giusti ◽  
F.T. Rantin ◽  
...  

1985 ◽  
Vol 114 (1) ◽  
pp. 37-51 ◽  
Author(s):  
M. L. Glass ◽  
R. G. Boutilier ◽  
N. Heisler

Freshwater turtles (Chrysemys picta bellii Gray) were acclimated to temperatures of 5, 10, 20 and 30°C for at least 12 days, and pulmonary ventilation, oxygen uptake and arterial pH, PCOCO2 and POO2 were determined in completely unrestrained specimens. Oxygen uptake (V·OO2) increased overproportionately (6.7-fold) as compared to pulmonary ventilation (V·1, 4.4-fold) when the temperature increased from 10 to 30°C. The observed rise in arterial PCOCO2 from 13 (5°C) to 32mmHg (30°C) was the result of a decrease in V·1/V·OO2, whereas an increase of arterial POO2 from 12Torr at 5°C to about 60Torr at 20 and 30°C mainly resulted from the effects of intracardiac blood shunting combined with temperature-dependent shifts of the oxygen dissociation curve. Arterial pH fell with rising temperature significantly less (ΔpH/Δt =−0.010U/°C) than required for constant relative alkalinity and for constant dissociation of imidazole. The changes of cerebrospinal fluid pH with temperature, calculated from the mean arterial PCOCO2 values, were even smaller [ΔpH/ΔtCSF = −0.008). It is concluded that the observed temperature dependence of the acid-base status is not in agreement with the alphastat hypothesis.


2008 ◽  
Vol 164 (3) ◽  
pp. 380-385 ◽  
Author(s):  
Glauber dos Santos Ferreira da Silva ◽  
Humberto Giusti ◽  
Adriana Paula Sanchez ◽  
Jussara Márcia do Carmo ◽  
Mogens Lesner Glass

1921 ◽  
Vol 33 (2) ◽  
pp. 201-222 ◽  
Author(s):  
J. H. Means ◽  
A. V. Bock ◽  
M. N. Woodwell

Carbon dioxide diagrams (Haggard and Henderson (9)) have been constructed for the blood of a series of hospital patients as a method of studying disturbances in their acid-base equilibrium. A diabetic with a low level of blood alkali, but with a normal blood reaction, a compensated acidosis in other words, showed a rapid return towards normal with no treatment but fasting and increased water and salt intake. A nephritic with a decompensated acidosis and a very low blood alkali was rapidly brought to a condition of decompensated alkalosis with a high blood alkali by the therapeutic administration of sodium bicarbonate. It is suggested that the therapeutic use of alkali in acidosis is probably only indicated in the decompensated variety, and that there it should be controlled carefully and the production of alkalosis avoided. The diagram obtained in three pneumonia patients suggested that they were suffering from a condition of carbonic acidosis, due perhaps to insufficient pulmonary ventilation. In two out of three cases of anemia the dissociation curve was found to lie at a higher level than normal. No explanation for this finding was offered.


2001 ◽  
Vol 290 (4) ◽  
pp. 421-425 ◽  
Author(s):  
Adriana Paula Sanchez ◽  
Anette Hoffmann ◽  
Francisco Tadeu Rantin ◽  
Mogens Lesner Glass

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