scholarly journals Prevalence, Associated Factors, and Prognostic Determinants of AIDS‐Related Toxoplasmic Encephalitis in the Era of Advanced Highly Active Antiretroviral Therapy

2004 ◽  
Vol 39 (11) ◽  
pp. 1681-1691 ◽  
Author(s):  
Andrea Antinori ◽  
Dora Larussa ◽  
Antonella Cingolani ◽  
Patrizia Lorenzini ◽  
Simona Bossolasco ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Associated Factors ◽  
Toxoplasmic Encephalitis ◽  
Highly Active

scholarly journals Viral Suppression and Its Associated Factors in HIV Patients on Highly Active Antiretroviral Therapy (HAART): A Retrospective Study in the Ho Municipality, Ghana

2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Sylvester Yao Lokpo ◽  
Patrick Jnr Ofori-Attah ◽  
Louis Selassie Ameke ◽  
Christian Obirikorang ◽  
Verner Ndudiri Orish ◽  
...  
Keyword(s):  
Viral Load ◽  
Medication Adherence ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Associated Factors ◽  
Viral Suppression ◽  
Similar Proportion ◽  
Clinic Attendance ◽  
Hiv Patients ◽  
Highly Active

Background. The WHO targets to end HIV/AIDS as a public health problem by 2030. The introduction of the ambitious “90-90-90” strategy to attain this target is expected to be achieved by the year 2020. However, there is lack of regional data, especially on the third “90.” This study sought to assess the rate and associated factors of viral suppression among people living with HIV (PLWH) on highly active antiretroviral therapy (HAART) at the Antiretroviral Therapy (ART) Clinic in a Ghanaian health facility. Method. The study design was a retrospective analysis of secondary data of 284 HIV registrants on HAART for at least 6 months at the ART Clinic from July 2016 to April 2019. Data on sociodemography including age, gender, marital status, education, and occupation as well as pharmacological (type of medication and duration on medication) and laboratory variable (current viral load results) were extracted from patients’ folders. Viral suppression and failure were determined using the WHO definitions (viral suppression as viral load <1000 copies/ml and virologic failure ≥1000 copies/ml). Regular clinic attendance (used as a proxy measure for medication adherence) was defined as consistent monthly clinic attendance for HAART medication and other clinical management within the past 12 months. Results. Out of the 284 HIV patients, 195 (69%) achieved viral suppression. Of the 195 who were virally suppressed, 77 (39.5%) had undetectable levels, with a similar proportion (39.5%) achieving viral load results ranging from 20 to 200 copies/ml. Moreover, 27 (13.8%) patients had viral load ranging from 201 to 500 copies/ml while 14 (7.2%) recorded viral load from 501 to 1000 copies/ml. No clear pattern in the viral suppression rate was associated with the age groups (p=0.1152). However, regular clinic attendance (used as proxy for medication adherence) (p<0.0001) and being on HAART for more than three (3) years (p=0.03) were associated with viral suppression. Conclusion. The rate of viral suppression among PLWH on HAART in the Ho municipality fell short of the WHO target. However, the study identified regular ART clinic attendance and treatment >3 years as factors associated with viral suppression.

HIV-1 Drug Resistance and Associated Factors Among Adults Failing First-Line Highly Active Antiretroviral Therapy in Ho Chi Minh City, Vietnam

2013 ◽  
Vol 14 (1) ◽  
pp. 34-44 ◽  
Author(s):  
Quang Duy Pham ◽  
Thu Khanh Hoang Huynh ◽  
Tram Thu Luong ◽  
Ton Tran ◽  
Thinh Xuan Vu ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Associated Factors ◽  
Ho Chi Minh City ◽  
First Line ◽  
Highly Active ◽  
Hiv 1
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