scholarly journals A Cohort Study of the Effectiveness of Influenza Vaccine in Older People, Performed Using the United Kingdom General Practice Research Database

2004 ◽  
Vol 190 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Punam Mangtani ◽  
Phillippa Cumberland ◽  
Cathy R. Hodgson ◽  
Jennifer A. Roberts ◽  
Felicity T. Cutts ◽  
...  
Keyword(s):  
General Practice ◽  
Cohort Study ◽  
United Kingdom ◽  
Influenza Vaccine ◽  
Older People ◽  
General Practice Research Database ◽  
Practice Research ◽  
Research Database ◽  
The United Kingdom

Epidemiology and cost of herpes zoster and post-herpetic neuralgia in the United Kingdom

2008 ◽  
Vol 137 (1) ◽  
pp. 38-47 ◽  
Author(s):  
A. GAUTHIER ◽  
J. BREUER ◽  
D. CARRINGTON ◽  
M. MARTIN ◽  
V. RÉMY
Keyword(s):  
General Practice ◽  
United Kingdom ◽  
Herpes Zoster ◽  
Retrospective Analysis ◽  
General Practice Research Database ◽  
Practice Research ◽  
Research Database ◽  
Post Herpetic Neuralgia ◽  
The United Kingdom ◽  
The Uk

SUMMARYRecent information on epidemiology and management of herpes zoster (HZ) and post-herpetic neuralgia (PHN), a painful complication of HZ, is scarce. The objective of this study was to document the burden of HZ and PHN in the United Kingdom. This retrospective analysis of the UK General Practice Research Database aimed to estimate HZ incidence and proportion of HZ patients developing PHN and to assess management costs in immunocompetent individuals aged ⩾50 years. A cohort of 27 225 HZ patients was selected, corresponding to an incidence of 5·23/1000 person-years. Respectively 19·5% and 13·7% of patients developed PHN at least 1 and 3 months after HZ diagnosis. Mean direct cost was £103 per HZ patient and £341 and £397 per PHN episode (1- and 3-month definition respectively). Both HZ and PHN costs increased markedly with pain severity. This study confirms that HZ and PHN are frequent and costly diseases in the United Kingdom.

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