Aminoglycoside Toxicity: Daily versus Thrice-Weekly Dosing for Treatment of Mycobacterial Diseases

C. A. Peloquin; S. E. Berning; A. T. Nitta; P. M. Simone; M. Goble; G. A. Huitt; M. D. Iseman; J. L. Cook; D. Curran-Everett

doi:10.1086/420742

Aminoglycoside Toxicity: Daily versus Thrice-Weekly Dosing for Treatment of Mycobacterial Diseases

Clinical Infectious Diseases ◽

10.1086/420742 ◽

2004 ◽

Vol 38 (11) ◽

pp. 1538-1544 ◽

Cited By ~ 129

Author(s):

C. A. Peloquin ◽

S. E. Berning ◽

A. T. Nitta ◽

P. M. Simone ◽

M. Goble ◽

...

Keyword(s):

Mycobacterial Diseases ◽

Aminoglycoside Toxicity

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LOSS-OF-FUNCTION OF THE PROTEIN KINASE C δ (PKC- δ) CAUSES MENDELIAN SUSCEPTIBILITY TO MYCOBACTERIAL DISEASES WITH RESPIRATORY BURST DEFECT

10.26226/morressier.57bc1754d462b80290b4d61f ◽

2016 ◽

Author(s):

Kunihiko Moriya

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Respiratory Burst ◽

Loss Of Function ◽

Kinase C ◽

Mycobacterial Diseases

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The double-sided effects of Mycobacterium Bovis bacillus Calmette–Guérin vaccine

npj Vaccines ◽

10.1038/s41541-020-00278-0 ◽

2021 ◽

Vol 6 (1) ◽

Author(s):

Junli Li ◽

Lingjun Zhan ◽

Chuan Qin

Keyword(s):

Literature Review ◽

Experimental Evidence ◽

Mycobacterium Bovis ◽

Virus Disease ◽

Bcg Vaccine ◽

Bacillus Calmette Guerin ◽

Mycobacterial Infections ◽

Specific Effects ◽

Mycobacterial Diseases ◽

Protection Mechanisms

AbstractBacillus Calmette–Guérin (BCG), the only vaccine proven to be effective against tuberculosis (TB), is the most commonly used vaccine globally. In addition to its effects on mycobacterial diseases, an increasing amount of epidemiological and experimental evidence accumulated since its introduction in 1921 has shown that BCG also exerts non-specific effects against a number of diseases, such as non-mycobacterial infections, allergies and certain malignancies. Recent Corona Virus Disease 2019 (COVID-19) outbreak has put BCG, a classic vaccine with significant non-specific protection, into the spotlight again. This literature review briefly covers the diverse facets of BCG vaccine, providing new perspectives in terms of specific and non-specific protection mechanisms of this old, multifaceted, and controversial vaccine.

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