The Lactoperoxidase System: Chemistry and Biological Significance.Kenneth M. Pruitt , Jorma O. Tenovuo

1986 ◽  
Vol 61 (1) ◽  
pp. 160-160
Author(s):  
Henry Rosen
Keyword(s):  
Lactoperoxidase System ◽  
System Chemistry

Inactivation of microbiota and selected spoilage and pathogenic bacteria in milk by combinations of ultrasound, hydrogen peroxide, and active lactoperoxidase system

2016 ◽  
Vol 61 ◽  
pp. 120-125 ◽  
Author(s):  
Ahamed Kamal Shamila-Syuhada ◽  
Li-Oon Chuah ◽  
Wan Abdullah Wan-Nadiah ◽  
Lai Hoong Cheng ◽  
Abbas F.M. Alkarkhi ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Pathogenic Bacteria ◽  
Lactoperoxidase System

scholarly journals The effect of activation of the lactoperoxidase system and souring on certain potential human pathogens in cows' milk

1997 ◽  
Vol 68 (4) ◽  
Author(s):  
J.G.K. Kangumba ◽  
E.H. Venter ◽  
J.A.W. Coetzer
Keyword(s):  
Rural Communities ◽  
Alternative Methods ◽  
Human Consumption ◽  
Socioeconomic Conditions ◽  
Human Pathogens ◽  
Pathogenic Potential ◽  
E Coli ◽  
Lactoperoxidase System ◽  
Potential Alternative ◽  
System Activation

Conventional methods of ensuring the safety and soundness of cows' milk for human consumption, such as pasteurisation, are not always practical in poor socioeconomic conditions or in rural communities that lack modern amenities. Activation of lactoperoxidase (LP) system and souring of milk were investigated as potential alternative methods to sustain the safety of milk by inhibiting certain microorganisms with known pathogenic potential. The activation of the LP-system inhibited the growth of Staphylococcus aureus and Escherichia coli by the order of 2 log values. The inhibition of Brucella abortus was negligible. The replication of Coxiella burnetti in milk was not disturbed even after 17 h of LP-system activation at 20 oC, but the outcome of the LP-system treatment on Mycobacterium bovis could not be determined as the conventional culturing technique used to grow this organism did not allow full recovery. Souring inhibited the growth of S. aureus and E. coli also by the order of 2 log values. From the results obtained in this investigation are concluded that the activation of the LP-system and souring can be used to inhibit the growth of S. aureus and E. coli in cows' milk, thereby increasing its safety.

scholarly journals HUBUNGAN ASUPAN ENERGI DAN ASUPAN LEMAK TERHADAP PROFIL LIPID PADA PENDERITA DISLIPIDEMIA

2019 ◽  
Vol 11 (25) ◽  
pp. 96-102
Author(s):  
Sugini
Keyword(s):  
Food Recall ◽  
Total P ◽  
System Chemistry

Latar Belakang : Asupan tinggi energi dari lemak jenuh meningkatkan risiko CHD khususnya pada wanita. Kelainan profil lipid ini erat hubungannya dengan proses perkembangan atherosklerosis. Penelitian epidemiologi, laboratorium dan klinik menunjukkan hubungan peningkatan kejadian penyakit kardiovaskular dan penyakit degeneratif lainnya dengan kadar kolesterol yang tinggi. Metode : Rancangan Penelitian adalah crossecional. Subyek penelitian adalah 30 karyawati RSUD Kendal umur 35 – 50 tahun.Pemeriksaan kadar kolesterol total, kadar kolesterol LDL diukur dengan vitros system chemistry analyser 300 di laboratorium patologi klinik RSUD Kendal. Asupan gizi diukur dengan metode food recall 24 dihitung dengan program Nutrisurvey. Analisis data menggunakan uji Shapiro Wilk dan uji korelasi Spearman. Hasil dan Pembahasan : Hasil analisa data adalah ada hubungan asupan energi dengan kadar kolesterol total (p=0,016, r=0,434), ada hubungan kuat asupan lemak dengan kadar kolesterol total (p=0,01, r=0,593), ada hubungan asupan lemak dengan kadar LDL (p=0,011, r=0,456) dan tidak ada hubungan asupan energi dengan kadar LDL (p=0,1119, r=0,291), Asupan tinggi energi mengakibatkan penimbunan lemak terutama trigliserida. Hal ini akan meningkatkan VLDL dan IDL darah yang akan berujung dengan peningkatan kolesterol total. Semakin tinggi seseorang mengkonsumsi makanan berlemak, maka timbunan kadar lemak dan trigliserida di dalam tubuh akan meningkat. Hal ini akan meningkatkan VLDL dan IDL darah. Simpulan : Ada hubungan asupan energi dengan kadar kolesterol total (p=0,016, r=0,434), ada hubungan kuat asupan lemak dengan kadar kolesterol total (p=0,01, r=0,593) dan kadar LDL (p=0,011, r=0,456).

scholarly journals Lactoperoxidase system in the dairy industry: Challenges and opportunities

2020 ◽  
Vol 38 (No. 6) ◽  
pp. 337-346
Author(s):  
Emmanuelle Silva ◽  
Juliana Oliveira ◽  
Yhelda Silva ◽  
Stela Urbano ◽  
Danielle Sales ◽  
...  
Keyword(s):  
Dairy Industry ◽  
Antimicrobial Properties ◽  
Quality Standard ◽  
Biological Properties ◽  
Scientific Publications ◽  
Promising Alternative ◽  
Action Mechanisms ◽  
Comprehensive Literature Review ◽  
Lactoperoxidase System ◽  
Challenges And Opportunities

The objective of this review was to search the literature for studies on the lactoperoxidase system (LPS) as milk natural preservation, action mechanisms, usage methods and perspectives for the dairy industry. A comprehensive literature review approach was conducted for collecting evidence in scientific publications. The biological properties of milk promote the development of microorganisms which compromise its quality, therefore demanding the use of techniques for preserving the milk matrix from its collection until processing. Within this context, LPS could represent an alternative to guarantee the safety of this food in are as where refrigeration is not possible; in addition, studies on applying this system in the dairy industry have been explored, as is the case in the test for verifying pasteurisation efficiency according to determining the lactoperoxidase enzyme activity. Natural antimicrobial properties of LPS make it a promising alternative for the industrial preservation and processing of milk, especially when considering the current quality standard demanded by the market. However, the potential of LPS as a biopreservative is still little technically and scientifically explored, which implies the need to develop new studies.

Atmospheric reactive oxygen species and some aspects of the antiviral protection of the respiratory epithelium

2021 ◽  
Vol 67 (5) ◽  
pp. 383-393
Author(s):  
V.V. Salmin ◽  
A.V. Morgun ◽  
R.Ya. Olovyannikova ◽  
V.A. Kutyakov ◽  
E.V. Lychkovskaya ◽  
...  
Keyword(s):  
Molecular Mechanisms ◽  
Expression Profiles ◽  
Respiratory Epithelium ◽  
Antibacterial Effects ◽  
Pharmacological Agents ◽  
Pathological Conditions ◽  
Lactoperoxidase System ◽  
Biochemical Mechanisms ◽  
Atmospheric Factors ◽  
Molecular And Biochemical Mechanisms

The review focuses on molecular and biochemical mechanisms of nonspecific protection of respiratory epithelium. The authors provide a comprehensive analysis of up-to-date data on the activity of the lactoperoxidase system expressed on the surface of the respiratory epithelium which provides the generation of hypothiocyanate and hypoiodite in the presence of locally produced or inhaled hydrogen peroxide. Molecular mechanisms of production of active compounds with antiviral and antibacterial effects, expression profiles of enzymes, transporters and ion channels involved in the generation of hypothiocyanite and hypoiodate in the mucous membrane of the respiratory system in physiological and pathological conditions (inflammation) are discussed. In the context of antibacterial and antiviral defense special attention is paid to recent data confirming the effects of atmospheric air composition on the efficiency of hypothiocyanite and hypoiodate synthesis in the respiratory epithelium. The causes and outcomes of lactoperoxidase system impairment due to the action of atmospheric factors are discussed in the context of controlling the sensitivity of the epithelium to the action of bacterial agents and viruses. Restoration of the lactoperoxidase system activity can be achieved by application of pharmacological agents aimed to compensate for the lack of halides in tissues, and by the control of chemical composition of the inhaled air.

Effect of Lactoperoxidase System on Keeping Quality of Raw Cow`s Milk in Thailand

2008 ◽  
Vol 3 (2) ◽  
pp. 112-116 ◽  
Author(s):  
Katekan Dajanta ◽  
Ekachai Chukeatiro ◽  
Arunee Apichartsr
Keyword(s):  
Lactoperoxidase System ◽  
Keeping Quality

Effects of Mono- and Disaccharides on the Antimicrobial Activity of Bovine Lactoperoxidase System

2011 ◽  
Vol 74 (1) ◽  
pp. 134-139 ◽  
Author(s):  
AHMAD NIMATULLAH AL-BAARRI ◽  
MAKOTO HAYASHI ◽  
MASAHIRO OGAWA ◽  
SHIGERU HAYAKAWA
Keyword(s):  
Antimicrobial Activity ◽  
Catalytic Activity ◽  
Kinetic Study ◽  
Salmonella Enteritidis ◽  
Sugar Content ◽  
The Other ◽  
Inhibitory Potency ◽  
Lactoperoxidase System ◽  
Noncompetitive Inhibitor

The effects of mono- and disaccharides on the antimicrobial activity of the lactoperoxidase (LPO) system against Salmonella Enteritidis were investigated. The results clearly reveal that most of the sugars inhibit the antimicrobial activity of the LPO system. The inhibitory potency varies depending on the structure of sugar. l-Fructose and d-allose were strongly inhibitive to the action of the LPO system, while sucrose was the weakest inhibitor. The decreased antimicrobial activity is due to the reduction of LPO catalytic activity by sugar. An inhibitory kinetic study showed the noncompetitive inhibitor. d-Allose and L-fructose yielded strikingly low Ki values of 0.36 and 0.42 mM, respectively, while the Ki values of the other sugars ranged from 1.37 to 3.60 mM. Since LPO activity is inhibited by the saccharides, the sugar content in food should be considered when the LPO system is applied to the preservation of food.

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