scholarly journals Tonsillopharyngitis Caused by Foodborne Group A Streptococcus: A Prison‐Based Outbreak

2003 ◽  
Vol 36 (2) ◽  
pp. 175-182 ◽  
Author(s):  
Michael Levy ◽  
Christine G. Johnson ◽  
Ed Kraa
Keyword(s):  
Group A Streptococcus ◽  
Group A ◽  
Streptococcus A

scholarly journals The most common causative bacteria in maternal sepsis-related deaths in Japan were group A Streptococcus: A nationwide survey

2019 ◽  
Vol 25 (1) ◽  
pp. 41-44 ◽  
Author(s):  
Hiroaki Tanaka ◽  
Shinji Katsuragi ◽  
Junichi Hasegawa ◽  
Kayo Tanaka ◽  
Kazuhiro Osato ◽  
...  
Keyword(s):  
Group A Streptococcus ◽  
Nationwide Survey ◽  
Group A ◽  
Maternal Sepsis ◽  
Streptococcus A

scholarly journals Biofilm formation by group A Streptococcus: a role for the streptococcal regulator of virulence (Srv) and streptococcal cysteine protease (SpeB)

Microbiology ◽  
2009 ◽  
Vol 155 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Christopher D. Doern ◽  
Amity L. Roberts ◽  
Wenzhou Hong ◽  
Jessica Nelson ◽  
Slawomir Lukomski ◽  
...  
Keyword(s):  
Cysteine Protease ◽  
Biofilm Formation ◽  
Group A Streptococcus ◽  
Immunoblot Analysis ◽  
Wild Type ◽  
Flow Conditions ◽  
Group A ◽  
Streptococcus A ◽  
Insight Into ◽  
Western Immunoblot Analysis

Recently, biofilms have become a topic of interest in the study of the human pathogen group A Streptococcus (GAS). In this study, we sought to learn more about the make-up of these structures and gain insight into biofilm regulation. Enzymic studies indicated that biofilm formation by GAS strain MGAS5005 required an extracellular protein and DNA component(s). Previous results indicated that inactivation of the transcriptional regulator Srv in MGAS5005 resulted in a significant decrease in virulence. Here, inactivation of Srv also resulted in a significant decrease in biofilm formation under both static and flow conditions. Given that production of the extracellular cysteine protease SpeB is increased in the srv mutant, we tested the hypothesis that increased levels of active SpeB may be responsible for the reduction in biofilm formation. Western immunoblot analysis indicated that SpeB was absent from MGAS5005 biofilms. Complementation of MGAS5005Δsrv restored the biofilm phenotype and eliminated the overproduction of active SpeB. Inhibition of SpeB with E64 also restored the MGAS5005Δsrv biofilm to wild-type levels.

scholarly journals Oral cavity swabbing for diagnosis of group a Streptococcus: a prospective study

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Limor Adler ◽  
Miriam Parizade ◽  
Gideon Koren ◽  
Ilan Yehoshua
Keyword(s):  
Oral Cavity ◽  
Prospective Study ◽  
Group A Streptococcus ◽  
Group A ◽  
A Prospective Study ◽  
Streptococcus A

An unusual presentation of group A streptococcus infection in a newborn: with acute mastoiditis with no obvious clinical manifestation

2017 ◽  
Vol 6 (2) ◽  
Author(s):  
Peymaneh Alizadeh Taheri ◽  
Mohsen Jafari ◽  
Fouzieh Mehrazmai
Keyword(s):  
Computed Tomography ◽  
Ct Scan ◽  
Clinical Manifestation ◽  
Group A Streptococcus ◽  
Term Neonate ◽  
Unusual Presentation ◽  
Acute Mastoiditis ◽  
Group A ◽  
Temporal Bones ◽  
Streptococcus A

Abstract Acute mastoiditis (AM) is rarely seen in newborns. It is characterized by retroauricular pain, swelling, tenderness and protrusion of the auricle. This is the first report of the neonatal mastoiditis in a 17-day-old term neonate with no obvious clinical manifestation of mastoiditis and no associated malformation of the ears and mastoids. A computed tomography (CT) scan of the temporal bones revealed right mastoiditis without osteitis, destruction of the mastoid bone or abscess formation. Discharge culture revealed streptococcus A colonies sensitive to ampicillin, ceftriaxone, vancomycin and chloramphenicol. She was successfully treated with intravenous ampicillin and ceftizoxime. No complication or recurrence was reported.

scholarly journals Perianal streptococcal disease in childhood: systematic literature review

2021 ◽  
Author(s):  
Renato Gualtieri ◽  
Gabriel Bronz ◽  
Mario G. Bianchetti ◽  
Sebastiano A. G. Lava ◽  
Elena Giuliano ◽  
...  
Keyword(s):  
Rectal Bleeding ◽  
Predictive Value ◽  
Group A Streptococcus ◽  
National Library ◽  
Asymptomatic Group ◽  
Time To Diagnosis ◽  
Long Time ◽  
Group A ◽  
Defecation Disorders ◽  
Streptococcus A

AbstractGroup A Streptococcus has been associated with a perianal infection. We conducted a systematic review of the literature on childhood streptococcal perianitis in three databases: Excerpta Medica, National Library of Medicine, and Web of Science. The main purposes were to document the clinical features, the tendency to recur, the association with an asymptomatic streptococcal throat carriage, the accuracy of rapid streptococcal tests, and the mechanism possibly underlying the acquisition of this infection. More than 80% of cases are boys ≤7.0 years of age with defecation disorders, perianal pain, local itch, rectal bleeding, or fissure and a sharply demarcated perianal redness. Perianitis is associated with a streptococcal tonsillopharyngitis in about every fifth case. The time to diagnosis is ≥3 weeks in 65% of cases. Recurrences occur within 3½ months in about 20% of cases. An asymptomatic group A streptococcal throat carriage occurs in 63% of cases. As compared with perianal Streptococcus A culture, the rapid streptococcal tests have a positive predictive value of 80% and a negative predictive value of 96%. It is hypothesized that digital inoculation from nasopharynx to anus underlies perianitis. Many cases are likely caused directly by children, who are throat and nasal carriers of Streptococcus A. Some cases might occur in children, who have their bottoms wiped by caregivers with streptococcal tonsillopharyngitis or carriage of Streptococcus.Conclusion: Perianitis is an infection with a distinctive presentation and a rather long time to diagnosis. There is a need for a wider awareness of this condition among healthcare professionals. What is Known:• Group A Streptococcus may cause perianitis in childhood.• Systemic antimicrobials (penicillin V, amoxycillin, or cefuroxime) are superior to topical treatment. What is New:• The clinical presentation is distinctive (defecation disorders, perianal pain, local itch, rectal bleeding, or fissure and a sharply demarcated perianal redness).• The time to diagnosis is usually ≥3 weeks.Recurrences occur in about 20% of cases.

Neonatal bacteremia caused by emm type 80 group A Streptococcus : A case report

2020 ◽  
Vol 62 (11) ◽  
pp. 1305-1306
Author(s):  
Yu Shinoda ◽  
Tomohiro Hori ◽  
Hideo Sasai ◽  
Tadayoshi Ikebe ◽  
Hidenori Ohnishi
Keyword(s):  
Case Report ◽  
Group A Streptococcus ◽  
Group A ◽  
Streptococcus A ◽  
Emm Type

Group A streptococcus: A continued threat

2006 ◽  
Vol 26 (7) ◽  
pp. 593-595 ◽  
Author(s):  
S. Hopkins ◽  
A. B. MaClean
Keyword(s):  
Group A Streptococcus ◽  
Group A ◽  
Streptococcus A

scholarly journals The feasibility of measuring calprotectin from a throat swab as a marker of infections caused by group A streptococcus: a case–control feasibility study

BJGP Open ◽  
2020 ◽  
Vol 4 (2) ◽  
pp. bjgpopen20X101006
Author(s):  
Behnaz Schofield ◽  
Clive Gregory ◽  
Micaela Gal ◽  
David Gillespie ◽  
Gurudutt Naik ◽  
...  
Keyword(s):  
Primary Care ◽  
Healthy Volunteers ◽  
Sore Throat ◽  
Throat Swab ◽  
Group A Streptococcus ◽  
Case Control ◽  
Antibiotic Prescribing ◽  
Group A ◽  
Primary Care Patients ◽  
Streptococcus A

BackgroundMost people with sore throat do not benefit from antibiotic treatment, but nearly three-quarters of those presenting in primary care are prescribed antibiotics. A test that is predictive of bacterial infection could help guide antibiotic prescribing. Calprotectin is a biomarker of neutrophilic inflammation, and may be a useful marker of bacterial throat infections.AimTo assess the feasibility of measuring calprotectin from throat swabs, and assess whether individuals with sore throats likely to be caused by streptococcal infections have apparently higher throat calprotectin levels than other individuals with sore throat and healthy volunteers.Design & settingA proof of concept case–control study was undertaken, which compared primary care patients with sore throats and healthy volunteers.MethodBaseline characteristics and throat swabs were collected from 30 primary care patients with suspected streptococcal sore throat, and throat swabs were taken from 10 volunteers without sore throat. Calprotectin level determination and rapid antigen streptococcal testing were conducted on the throat swab eluents. Calprotectin levels in the following groups were compared: volunteers without a sore throat; all patients with a sore throat; patients with a sore throat testing either negative or positive for streptococcal antigen; and those with lower and higher scores on clinical prediction rules for streptococcal sore throat.ResultsCalprotectin was detected in all throat swab samples. Mean calprotectin levels were numerically higher in patients with sore throat compared with healthy volunteers, and sore throat patients who had group A streptococci antigen detected compared with those who did not.ConclusionCalprotectin can be measured from throat swab samples and levels are consistent with the hypothesis that streptococcal infection leads to higher throat calprotectin levels. This hypothesis will be tested in a larger study.

Sign in / Sign up

Export Citation Format

Share Document