scholarly journals Cytomegalovirus Glycoprotein B Groups in Human Immunodeficiency Virus–Infected Patients with Incident Retinitis

2002 ◽  
Vol 186 (1) ◽  
pp. 114-117 ◽  
Author(s):  
W. Lawrence Drew ◽  
Sunwen Chou ◽  
Richard C. Miner ◽  
Beth A. Mohr ◽  
Michael P. Busch ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Glycoprotein B ◽  
Immunodeficiency Virus

scholarly journals Salivary Cytomegalovirus (CMV) Shedding, Glycoprotein B Genotype Distribution, and CMV Disease in Human Immunodeficiency Virus–Seropositive Patients

2001 ◽  
Vol 33 (8) ◽  
pp. 1406-1411 ◽  
Author(s):  
N. Fidouh‐Houhou ◽  
X. Duval ◽  
F. Bissuel ◽  
V. Bourbonneux ◽  
P. Flandre ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Glycoprotein B ◽  
Genotype Distribution ◽  
Immunodeficiency Virus ◽  
Cmv Disease

scholarly journals Candidate Topical Microbicides Bind Herpes Simplex Virus Glycoprotein B and Prevent Viral Entry and Cell-to-Cell Spread

2004 ◽  
Vol 48 (6) ◽  
pp. 2025-2036 ◽  
Author(s):  
Natalia Cheshenko ◽  
Marla J. Keller ◽  
Veronica MasCasullo ◽  
Gary A. Jarvis ◽  
Hui Cheng ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Glycoprotein B ◽  
Resistant Variant ◽  
Herpes Simplex Virus Glycoprotein ◽  
Immunodeficiency Virus ◽  
Topical Microbicides ◽  
Simplex Virus ◽  
Cell Spread

ABSTRACT Topical microbicides designed to prevent acquisition of sexually transmitted infections are urgently needed. Nonoxynol-9, the only commercially available spermicide, damages epithelium and may enhance human immunodeficiency virus transmission. The observation that herpes simplex virus (HSV) and human immunodeficiency virus bind heparan sulfate provided the rationale for the development of sulfated or sulfonated polymers as topical agents. Although several of the polymers have advanced to clinical trials, the spectrum and mechanism of anti-HSV activity and the effects on soluble mediators of inflammation have not been evaluated. The present studies address these gaps. The results indicate that PRO 2000, polystyrene sulfonate, cellulose sulfate, and polymethylenehydroquinone sulfonate inhibit HSV infection 10,000-fold and are active against clinical isolates, including an acyclovir-resistant variant. The compounds formed stable complexes with glycoprotein B and inhibit viral binding, entry, and cell-to-cell spread. The effects may be long lasting due to the high affinity and stability of the sulfated compound-virus complex, as evidenced by surface plasmon resonance studies. The candidate microbicides retained their antiviral activities in the presence of cervical secretions and over a broad pH range. There was little reduction in cell viability following repeated exposure of human endocervical cells to these compounds, although a reduction in secretory leukocyte protease inhibitor levels was observed. These studies support further development and rigorous evaluation of these candidate microbicides.

Human Immunodeficiency Virus (HIV) Infection in Children

1987 ◽  
Vol 1 (3) ◽  
pp. 381-395 ◽  
Author(s):  
Beverly Ryan ◽  
Edward Connor ◽  
Anthony Minnefor ◽  
Frank Desposito ◽  
James Oleske
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hiv Infection ◽  
Immunodeficiency Virus

Effect of Human Immunodeficiency Virus on the Outcome of Hepatitis C Virus Infection

2001 ◽  
Vol 36 (3) ◽  
pp. 225-234
Author(s):  
Ramazan Idilman ◽  
Alessandra Colantoni ◽  
Nicola De Maria ◽  
James M. Harig ◽  
David H. van Thiel
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Hepatitis C Virus Infection ◽  
Immunodeficiency Virus

Rapid diameter expansion of aortic aneurysm after human immunodeficiency virus infection

VASA ◽  
2015 ◽  
Vol 44 (5) ◽  
pp. 387-390
Author(s):  
Thomas Kotsis ◽  
Louizos-Alexandros Louizos ◽  
Spyridon Mylonas ◽  
Evangelos Pappas ◽  
Karandrea Despoina ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Aortic Aneurysm ◽  
Virus Infection ◽  
Human Immunodeficiency Virus Infection ◽  
Immunodeficiency Virus
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