scholarly journals Hepatitis C Virus Prevalence among Patients Infected with Human Immunodeficiency Virus: A Cross-Sectional Analysis of the US Adult AIDS Clinical Trials Group

2002 ◽  
Vol 34 (6) ◽  
pp. 831-837 ◽  
Author(s):  
Kenneth E. Sherman ◽  
Susan D. Rouster ◽  
Raymond T. Chung ◽  
Natasa Rajicic
Keyword(s):  
Human Immunodeficiency Virus ◽  
Clinical Trials ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Cross Sectional ◽  
Virus Prevalence ◽  
Immunodeficiency Virus ◽  
The Us ◽  
Aids Clinical Trials ◽  
Sectional Analysis

scholarly journals Prevalence and Characteristics of Hepatitis C Virus Coinfection in a Human Immunodeficiency Virus Clinical Trials Group: The Terry Beirn Community Programs for Clinical Research on AIDS

2003 ◽  
Vol 36 (10) ◽  
pp. 1313-1317 ◽  
Author(s):  
Ellen M. Tedaldi ◽  
Katherine Huppler Hullsiek ◽  
Carlos D. Malvestutto ◽  
Roberto C. Arduino ◽  
Evelyn J. Fisher ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Clinical Trials ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Clinical Research ◽  
Community Programs ◽  
Immunodeficiency Virus

scholarly journals FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KECELAKAAN KERJA TERTUSUK JARUM SUNTIK ATAU BENDA TAJAM LAINNYA PADA PERAWAT DI RSUD LEUWILIANG KABUPATEN BOGOR TAHUN 2018

PROMOTOR ◽  
2019 ◽  
Vol 2 (2) ◽  
pp. 163
Author(s):  
Sylvia Puspitasari ◽  
Supriyanto . ◽  
Rubi Ginanjar
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Random Sampling ◽  
Simple Random Sampling ◽  
P Value ◽  
Needle Stick Injury ◽  
Cross Sectional ◽  
B Virus ◽  
Immunodeficiency Virus

<p>Petugas kesehatan berisiko tertular penyakit dari darah/cairan tubuh (bloodborne pathogen) melalui berbagai cara, salah satunya melalui luka tusuk jarum atau yang dikenal dengan istilah Needle Stick Injury (NSI). Risiko yang dapat terjadi jika tertusuk jarum dapat menimbulkan infeksi HBV<br />(Hepatitis B Virus), HCV (Hepatitis C Virus) dan HIV (Human Immunodeficiency Virus). Tujuan dari penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan kecelakaan kerja tertusuk jarum suntik atau benda tajam lainnya pada Perawat di RSUD Leuwiliang Kabupaten Bogor tahun 2018. Penelitian ini menggunakan desain studi cross sectional. Teknik pengambilan sampel menggunakan simple random sampling dengan jumlah responden sebanyak 71 orang. Pengambilan data dalam penelitian ini menggunakan kuesioner dan menganalisis data dengan uji statistik chisquare<br />menggunakan perangkat lunak aplikasi statistic (SPSS 16). Hasil penelitian menunjukkan bahwa tidak ada hubungan antara tindakan tidak aman (p-value = 0,461), kondisi tidak aman (p-value = 0,301, masa kerja (p-value = 0,757), pengetahuan (p-value = 0,190), pengawasan (p-value = 0,090)<br />dengan kecelakaan kerja tertusuk jarum suntik atau benda tajam lainnya. Sedangkan untuk variabel lainnya, ada hubungan antara keterampilan (p-value = 0,010) OR = 0,237 (95% CI: 0,085-0,662), pelatihan (p value = 0,022) OR = 3,566 (95% CI: 1,313-9,688) dengan kecelakaan kerja tertusuk<br />jarum suntik atau benda tajam lainnya. Kesimpulan penelitian ini adalah kurangnya keterampilan dan pelatihan mempengaruhi perawat dalam kecelakaan kerja, karena keterampilan dan pelatihan dibutuhkan seseorang dalam setiap pekerjaan untuk meningkatkan kemampuan dan keahliannya<br />sehingga mampu menyelesaikan tugas dengan baik dan dapat terhindar dari risiko kecelakaan kerja</p>

scholarly journals Soluble T-Cell Immunoglobulin Mucin Domain-3 Is Associated With Hepatitis C Virus Coinfection and Low-Grade Inflammation During Chronic Human Immunodeficiency Virus Infection

2020 ◽  
Vol 7 (2) ◽  
Author(s):  
Hedda Hoel ◽  
Thor Ueland ◽  
Malene Hove-Skovsgaard ◽  
Hans Jakob Hartling ◽  
Marco Gelpi ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
T Cell ◽  
Virus Infection ◽  
Cross Sectional ◽  
Art Initiation ◽  
Immune Exhaustion ◽  
Immunodeficiency Virus ◽  
Domain 3

Abstract Background In well treated human immunodeficiency virus infection (HIV), there is a residual immune activation and immune exhaustion that may contribute to increased risk of comorbidities. T-cell immunoglobulin mucin domain-3 (Tim-3) is an inhibitory molecule involved in HIV-associated T-cell dysfunction. The Tim-3 can be cleaved to soluble Tim-3 (sTim-3) that may serve as a soluble marker of immune exhaustion. Methods We measured sTim-3 with enzyme-linked immunosorbent assay DuoSets in a cross-sectional cohort of 1010 people with HIV (PWH) on antiretroviral therapy (ART), and 76 controls from the Copenhagen Co-Morbidity in HIV Infection (COCOMO) study, and in a longitudinal cohort of 60 PWH before and during ART. Results In the cross-sectional cohort, levels of sTim-3 were elevated in PWH on ART compared with controls, especially in hepatitis C virus (HCV)-coinfected individuals, and were associated with HCV viremia and inflammation. In the longitudinal cohort, pretreatment sTim-3 correlated with HIV viral load and decreased after ART initiation. Pretreatment sTim-3 correlated inversely with CD4 counts, but it did not predict immunological response in multivariable analyses. Conclusions Levels of sTim-3 decreased after ART initiation. In a cross-sectional cohort, levels of sTIM-3 were higher in PWH than in controls and were independently associated with HCV coinfection and high-sensitivity C-reactive protein, representing a potential link between immune exhaustion, inflammation, and risk of comorbidities.

scholarly journals Seroprevalence of hepatitis B virus, hepatitis C virus and human immunodeficiency virus in the western region of Nepal

2017 ◽  
Vol 5 (1) ◽  
pp. 6-10
Author(s):  
Umid Kumar Shrestha ◽  
Bhup Dev Bhatta
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Western Region ◽  
Cross Sectional ◽  
B Virus ◽  
Immunodeficiency Virus ◽  
The Western Region

Background and aims: The hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) are associated with major public health concerns. The aim of the study was to determine the seroprevalence of HBV, HCV and HIV in the western region of Nepal.Methods: This was a cross-sectional observational study, in which 15,791 patients, attending to Manipal Teaching Hospital, Pokhara, Nepal, were investigated for HBV, HCV and HIV from June 2013 to March 2016; demographic and biochemical profile were studied among the patients with positive test results.Results: Among 15,791 patients [male 6614 (41.9%) and female 9177 (58.1%)], HBV was found in 180 (1.1%), HCV in 52 (0.3%) and HIV in 77 (0.5%). The HBV was found in 63.9% of males and 36.1% of females, HCV in 67.3% of males and 32.7% of females, and HIV in 61% of males and 39% of females which showed that males had more positivity of HBV (P<0.001), HCV (P<0.001) and HIV (P 0.001) than that of female. The HBV was found more in 20-29 years age group (27.2%), HCV in 30-39 years (32.7%), and HIV in 40-49 years (28.6%), with all having p<0.001. Among the patients of HBV, HCV and HIV, the mean values of total bilirubin were 1.4 mg/dl, 0.8 mg/dl and 2.6 mg/dl, Aspartate Transaminase 75.9 U/L, 54.3 U/L and 92.7 U/L, Alanine Transaminase 54.6 U/L, 55.5 U/L and 56.1 U/L, and Alkaline Phosphatase 124.2 U/L, 109.2 U/L and 107.2 U/L, respectively. The majority of patients with HCV had a history of intravenous drug abuse and HIV had concomitant alcoholic liver disease.Conclusion: The HBV was more prevalent followed by HIV and HCV in the western region of Nepal with more prevalence seen in males than in females. Regular screening of HBV, HCV and HIV among the selected patients can help detecting many new cases in Nepal.Journal of Advances in Internal Medicine 2016;05(01):6-10

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