scholarly journals Intravenous Itraconazole Followed by Oral Itraconazole in the Treatment of Invasive Pulmonary Aspergillosis in Patients with Hematologic Malignancies, Chronic Granulomatous Disease, or AIDS

2001 ◽  
Vol 33 (8) ◽  
pp. e83-e90 ◽  
Author(s):  
D. Caillot ◽  
H. Bassaris ◽  
A. McGeer ◽  
C. Arthur ◽  
H. G. Prentice ◽  
...  
Keyword(s):  
Chronic Granulomatous Disease ◽  
Invasive Pulmonary Aspergillosis ◽  
Hematologic Malignancies ◽  
Granulomatous Disease ◽  
Pulmonary Aspergillosis ◽  
Oral Itraconazole

scholarly journals A Case of Chronic Granulomatous Disease with a Necrotic Mass in the Bronchus: A Case Report and a Review of Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Ali Cheraghvandi ◽  
Majid Marjani ◽  
Saeid Fallah Tafti ◽  
Logman Cheraghvandi ◽  
Davoud Mansouri
Keyword(s):  
Case Report ◽  
Chronic Granulomatous Disease ◽  
Medical Therapy ◽  
Unusual Case ◽  
Fungal Infections ◽  
Invasive Pulmonary Aspergillosis ◽  
Granulomatous Disease ◽  
Review Of Literature ◽  
Pulmonary Aspergillosis ◽  
The Right

Chronic granulomatous disease is a rare phagocytic disorder with recurrent, severe bacterial and fungal infections. We describe an unusual case of chronic granulomatous disease manifesting as an invasive pulmonary aspergillosis with an obstructive necrotic mass at the right middle bronchus. The patient was successfully treated with a bronchoscopic intervention for the removal of the obstructive mass and a medical therapy.

Failure To Detect Circulating Aspergillus Markers in a Patient with Chronic Granulomatous Disease and Invasive Aspergillosis

2000 ◽  
Vol 38 (10) ◽  
pp. 3900-3901 ◽  
Author(s):  
Paul E. Verweij ◽  
Corry M. Weemaes ◽  
Jo H. A. J. Curfs ◽  
Stephane Bretagne ◽  
Jacques F. G. M. Meis
Keyword(s):  
Invasive Aspergillosis ◽  
Chronic Granulomatous Disease ◽  
Invasive Pulmonary Aspergillosis ◽  
Granulomatous Disease ◽  
Subphrenic Abscess ◽  
Pulmonary Aspergillosis ◽  
Circulating Antigen

We report a patient with chronic granulomatous disease who developed invasive pulmonary aspergillosis and a subphrenic abscess. During treatment, high levels of Aspergillus antigen were detected in the abscess, but circulating antigen andAspergillus DNA were undetectable in the serum.

A neonatal case of chronic granulomatous disease, initially presented with invasive pulmonary aspergillosis

2014 ◽  
Vol 20 (3) ◽  
pp. 220-223 ◽  
Author(s):  
Sachiko Saito ◽  
Arata Oda ◽  
Masashi Kasai ◽  
Kisei Minami ◽  
Haruo Nagumo ◽  
...  
Keyword(s):  
Chronic Granulomatous Disease ◽  
Invasive Pulmonary Aspergillosis ◽  
Granulomatous Disease ◽  
Pulmonary Aspergillosis

Successful Medical Therapy of Aspergillus Osteomyelitis of the Spine in an 11-Year-Old Boy With Chronic Granulomatous Disease

PEDIATRICS ◽  
1994 ◽  
Vol 93 (5) ◽  
pp. 830-835
Author(s):  
Mark W. Kline ◽  
Mary E. Paul ◽  
Howard M. Rosenblatt ◽  
William T. Shearer ◽  
Florante C. Bocobo
Keyword(s):  
Chronic Granulomatous Disease ◽  
Vertebral Osteomyelitis ◽  
Granulomatous Disease ◽  
Lipid Complex ◽  
Serious Infection ◽  
Common Causes ◽  
Oral Itraconazole ◽  
Amphotericin B Lipid Complex ◽  
Intravenous Amphotericin ◽  
Contiguous Spread

Aspergillus is one of the most common causes of serious infection and death in individuals with chronic granulomatous disease (CGD).1 Clinically evident infection often begins in the lung with pneumonia; contiguous spread or dissemination of infection may occur. Vertebral osteomyelitis in individuals with CGD usually is caused by Aspergillus.2 Unfortunately, despite aggressive medical and surgical therapy of this condition, reported cases have been associated with treatment failure, recurrence, severe disabling orthopedic or neurologic complications and death.2-5 In this report we describe a unique case in which therapy with intravenous amphotericin B lipid complex (AmBLC), oral itraconazole, and granulocyte transfusions resulted in complete clinical and radiographic resolution of Aspergillus fumigatus osteomyelitis of the spine.

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