scholarly journals Development, Acceptance, and Use of Immunologic Correlates of Protection in Monitoring the Effectiveness of Combination Vaccines

2001 ◽  
Vol 33 (s4) ◽  
pp. S274-S277 ◽  
Author(s):  
Kathryn M. Edwards
Keyword(s):  
Correlates Of Protection ◽  
Combination Vaccines

Combination Vaccines: Simpler or More Complex?

2007 ◽  
Vol 37 (13) ◽  
pp. 16
Author(s):  
MICHAEL E. PICHICHERO
Keyword(s):  
Combination Vaccines

scholarly journals 1400. Physician Attitudes towards Combination Vaccine Use in Infants up to 24 months of age in the United States (US)

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S708-S709
Author(s):  
Ya-Ting Chen ◽  
Xinyi Ng ◽  
Tanaz Petigara ◽  
Jyoti Aggarwal ◽  
Jenna Bhaloo ◽  
...  
Keyword(s):  
Research Study ◽  
Scientific Research ◽  
Physician Attitudes ◽  
Combination Vaccine ◽  
Hexavalent Vaccine ◽  
Family Practitioners ◽  
Study Investigator ◽  
Vaccine Schedule ◽  
Combination Vaccines ◽  
Number Of Injections

Abstract Background Combination vaccines reduce the number of injections and improve the timeliness of vaccination coverage. US Advisory Committee on Immunization Practices (ACIP) recommendations state that combination vaccines are generally preferred over equivalent individual component vaccines. Healthcare providers strongly influence parental decisions about vaccination. We sought a contemporary understanding of physician’s attitudes towards combination vaccine use in infants. Methods We conducted an online survey of US physicians (70 pediatricians and 30 family practitioners) who administer vaccines to infants aged 0-24 months and spend at least 2 days a week providing patient care. Information was collected on attitudes towards combination vaccines and factors that influence the choice of combination vaccine used in clinical practice. Descriptive analyses were performed. Results Physicians (mean age=50.2 years, range 30.0-70.0; 66% white; 37% women) reported a median of 4 injections (range 2-9) as the maximum that parents would accept at a single visit, and 71% routinely explained what combination vaccines are to parents. When deciding which pentavalent vaccine to use, physicians considered how the brand fits into the current vaccine schedule (71%); upfront purchase costs (64%); and availability as a prefilled syringe (61%). The main reasons for using combination vaccines were to reduce the number of injections (96%); ensure the infant is up-to-date with vaccinations (86%); and reduce the pain that the infant experiences with multiple injections (68%). More than half reported that their institution or practice has a program to incentivize infant vaccination according to schedule. If a hexavalent vaccine-based schedule was available, 76% of physicians said they would choose it over their current schedule comprising pentavalent or equivalent component vaccines. Conclusion Choice of pentavalent combination vaccine among pediatricians and family practitioners was largely dependent on convenience and cost-related factors. Over three-quarters would be inclined to use a hexavalent vaccine schedule if available. Disclosures Ya-Ting Chen, PhD, Merck & Co., Inc. (Employee, Shareholder) Xinyi Ng, PhD, Merck & Co., Inc. (Consultant) Tanaz Petigara, PhD, Merck & Co., Inc. (Employee, Shareholder) Jyoti Aggarwal, MHS, Merck & Co., Inc. (Consultant) Jenna Bhaloo, MPH, Merck & Co., Inc. (Consultant) Michelle Goveia, MD, Merck & Co., Inc (Employee, Shareholder) David Johnson, MD, MPH, Sanofi Pasteur (Employee, Shareholder) Gary S. Marshall, MD, GlaxoSmithKline (Consultant, Scientific Research Study Investigator)Merck (Consultant, Scientific Research Study Investigator)Pfizer (Consultant, Scientific Research Study Investigator)Sanofi Pasteur (Consultant, Grant/Research Support, Scientific Research Study Investigator, Honorarium for conference lecture)Seqirus (Consultant, Scientific Research Study Investigator)

Antibodies to parvovirus, distemper virus and adenovirus conferred to household dogs using commercial combination vaccines containing Leptospira bacterin

2010 ◽  
Vol 167 (24) ◽  
pp. 931-934 ◽  
Author(s):  
M. Taguchi ◽  
K. Namikawa ◽  
T. Maruo ◽  
J. Lynch ◽  
H. Sahara
Keyword(s):  
Combination Vaccines

Correlates of Protection Following Vaccination with Inactivated Porcine Circovirus 2 Vaccines

2015 ◽  
Vol 28 (10) ◽  
pp. 600-608 ◽  
Author(s):  
Cinzia Zanotti ◽  
Nicola Martinelli ◽  
Davide Lelli ◽  
Massimo Amadori
Keyword(s):  
Porcine Circovirus ◽  
Correlates Of Protection ◽  
Porcine Circovirus 2

Predictive models and correlates of protection for testing biodefence vaccines

2010 ◽  
Vol 9 (5) ◽  
pp. 527-537 ◽  
Author(s):  
E Diane Williamson ◽  
MG Duchars ◽  
Robert Kohberger
Keyword(s):  
Predictive Models ◽  
Correlates Of Protection
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