scholarly journals Distinct Mutations in the Receptor Tyrosine Kinase Gene ROR2 Cause Brachydactyly Type B

2000 ◽  
Vol 67 (4) ◽  
pp. 822-831 ◽  
Author(s):  
Georg C. Schwabe ◽  
Sigrid Tinschert ◽  
Christian Buschow ◽  
Peter Meinecke ◽  
Gerhard Wolff ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Receptor Tyrosine Kinase ◽  
Type B ◽  
Kinase Gene ◽  
Tyrosine Kinase Gene ◽  
Receptor Tyrosine Kinase Gene

FLT4 Receptor Tyrosine Kinase Gene Mapping to Chromosome Band 5q35 in Relation to the t(2;5), t(5;6), and t(3;5) Translocations

1993 ◽  
Vol 7 (3) ◽  
pp. 144-151 ◽  
Author(s):  
Elina Armstrong ◽  
Kumar Kastury ◽  
Olga Aprelikova ◽  
Florencia Bullrich ◽  
Christian Nezelof ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Gene Mapping ◽  
Receptor Tyrosine Kinase ◽  
Chromosome Band ◽  
Kinase Gene ◽  
Tyrosine Kinase Gene ◽  
Receptor Tyrosine Kinase Gene

scholarly journals Multiple functions of let-23, a Caenorhabditis elegans receptor tyrosine kinase gene required for vulval induction.

Genetics ◽  
1991 ◽  
Vol 128 (2) ◽  
pp. 251-267 ◽  
Author(s):  
R V Aroian ◽  
P W Sternberg
Keyword(s):  
Caenorhabditis Elegans ◽  
Tyrosine Kinase ◽  
Receptor Tyrosine Kinase ◽  
Egf Receptor ◽  
Kinase Gene ◽  
Multiple Functions ◽  
Tyrosine Kinase Gene ◽  
Receptor Tyrosine Kinase Gene ◽  
Epidermal Growth ◽  
Mutant Phenotypes

Abstract The let-23 gene, which encodes a putative tyrosine kinase of the epidermal growth factor (EGF) receptor subfamily, has multiple functions during Caenorhabditis elegans development. We show that let-23 function is required for vulval precursor cells (VPCs) to respond to the signal that induces vulval differentiation: a complete loss of let-23 function results in no induction. However, some let-23 mutations that genetically reduce but do not eliminate let-23 function result in VPCs apparently hypersensitive to inductive signal: as many as five of six VPCs can adopt vulval fates, in contrast to the three that normally do. These results suggest that the let-23 receptor tyrosine kinase controls two opposing pathways, one that stimulates vulval differentiation and another that negatively regulates vulval differentiation. Furthermore, analysis of 16 new let-23 mutations indicates that the let-23 kinase functions in at least five tissues. Since various let-23 mutant phenotypes can be obtained independently, the let-23 gene is likely to have tissue-specific functions.

scholarly journals The receptor tyrosine kinase gene linotte is required for neuronal pathway selection in the Drosophila mushroom bodies

1998 ◽  
Vol 78 (1-2) ◽  
pp. 47-61 ◽  
Author(s):  
Caroline Moreau-Fauvarque ◽  
Emmanuel Taillebourg ◽  
Elisabeth Boissoneau ◽  
Jacqueline Mesnard ◽  
Jean-Maurice Dura
Keyword(s):  
Tyrosine Kinase ◽  
Receptor Tyrosine Kinase ◽  
Mushroom Bodies ◽  
Kinase Gene ◽  
Neuronal Pathway ◽  
Tyrosine Kinase Gene ◽  
Receptor Tyrosine Kinase Gene

Genomic Structure and Promoter Analysis of the Mouse EphA8 Receptor Tyrosine Kinase Gene

2000 ◽  
Vol 19 (5) ◽  
pp. 291-300 ◽  
Author(s):  
Jaemin Jeong ◽  
Sunga Choi ◽  
Changkyu Gu ◽  
Hansoo Lee ◽  
Soochul Park
Keyword(s):  
Tyrosine Kinase ◽  
Receptor Tyrosine Kinase ◽  
Promoter Analysis ◽  
Genomic Structure ◽  
Kinase Gene ◽  
Tyrosine Kinase Gene ◽  
Receptor Tyrosine Kinase Gene

scholarly journals The HER-2/neu receptor tyrosine kinase gene encodes a secreted autoinhibitor

1999 ◽  
Vol 96 (19) ◽  
pp. 10869-10874 ◽  
Author(s):  
J. K. Doherty ◽  
C. Bond ◽  
A. Jardim ◽  
J. P. Adelman ◽  
G. M. Clinton
Keyword(s):  
Tyrosine Kinase ◽  
Receptor Tyrosine Kinase ◽  
Kinase Gene ◽  
Tyrosine Kinase Gene ◽  
Receptor Tyrosine Kinase Gene ◽  
Her 2
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