Social Psychology.Knight DunlapAn Introduction to Social Psychology.L. L. BernardOutlines of Abnormal Psychology.William McDougallProblems of Personality. Studies Presented to Dr. Morton Prince, Pioneer in American Psychopathology.C. MacFie Campbell , H. S. Langfeld , William McDougall , R. A. Roback , E. W. TaylorThe Meaning of Psychology.C. K. OgdenBrains of Rats and Men. A Survey of the Origin and Biological Significance of the Cerebral Cortex.C. Judson Herrick

1926 ◽  
Vol 32 (3) ◽  
pp. 482-486
Author(s):  
Ellsworth Faris
Author(s):  
Vitthal S. Kulkarni ◽  
Wayne H. Anderson ◽  
Rhoderick E. Brown

The biological significance of the sphingomyelins (SM) and monoglycosylated sphingolipids like galactosylceramides (GalCer) are well documented Our recent investigation showed tubular bilayers in the aqueous dispersions of N-nervonoyl GalCer [N-(24:lΔ15,cls) GalCer] (a major fatty acyl moiety of natural GalCer). To determine the influence of lipid head groups on the resulting mesophasic morphology, we investigated microstructural self-assemblies of N-nervonoyl-SM [N-(24:1 Δ15,cls) SM; the second most abundant sphingomyelin in mammalian cell membranes], 1- palmitoyl-2-nervonoyl phosphatidylcholine [PNPC] (the lipid species with the same acyl chain configuration as in N-(24: 1) GalCer) and also compared it with egg-SM by freeze-fracture EM.Procedures for synthesizing and purifying N-(24:1) GalCer, N-(24:1) SM, and PNPC have been reported . Egg-SM was purchased from Avanti Polar Lipids, Alabaster AL. All lipids were >99% pure as checked by thin layer chromatography. Lipid dispersions were prepared by hydrating dry lipid with phosphate buffer (pH 6.6) at 80-90°C (3-5 min), vigorously vortexing (1 min) and repeating this procedure for three times prior to three freeze-thaw cycles.


Author(s):  
Dong Yuming ◽  
Yang Guanglin ◽  
Wu Jifeng ◽  
Chen Xiaolin

On the basis of light microscopic observation, the ultrastructural localization of CEA in gastric cancer was studied by immunoelectron microscopic technique. The distribution of CEA in gastric cancer and its biological significance and the mechanism of abnormal distribution of CEA were further discussed.Among 104 surgically resected specimens of gastric cancer with PAP method at light microscopic level, the incidence of CEA(+) was 85.58%. All of mucinous carcinoma exhibited CEA(+). In tubular adenocarcinoma the incidence of CEA(+) showed a tendency to rising with the increase of degree of differentiation. In normal epithelia and intestinal metaplasia CEA was faintly present and was found only in the luminal surface. The CEA staining patterns in cancer cells were of three types--- cytoplasmic, membranous and weak reactive type. The ultrastructural localization of CEA in 14 cases of gastric cancer was studied by immunoelectron microscopic technique.There was a little or no CEA in the microvilli of normal epithelia. In intestinal metaplasia CEA was found on the microvilli of absorptive cells and among the mucus particles of goblet cells. In gastric cancer CEA was also distributed on the lateral and basal surface or even over the entire surface of cancer cells and lost their polarity completely. Many studies had proved that the alterations in surface glycoprotein were characteristic changes of tumor cells. The antigenic determinant of CEA was glycoprotein, so the alterations of tumor-associated surface glycoprotein opened up a new way for the diagnosis of tumors.


1973 ◽  
Vol 74 (Suppl) ◽  
pp. S130-S167 ◽  
Author(s):  
O. P. Samarina ◽  
E. M. Lukanidin ◽  
G. P. Georgiev

ABSTRACT This paper is a review of the data concerning the nature, structural organization, properties and biological significance of the particles, containing mRNA and pre-mRNA (precursor of mRNA), i. e., (1) nuclear pre-mRNA-containing particles (2) free cytoplasmic mRNP (ribonucleoproteins), or informosomes (3) polysome-bound mRNP. Some new data on the comparison of nuclear and cytoplasmic particles, the nature of poly A-containing structures, involvement of informofers in Adenovirusspecific RNA transfer are presented. The general scheme of mRNA transport from nucleus to cytoplasm is discussed.


2010 ◽  
Vol 17 (1) ◽  
pp. 17-30 ◽  
Author(s):  
Katarzyna J. Chwedorzewska

ABSTRACTThe geographic position, astronomic factors (e.g. the Earth’s maximum distance from the Sun during winter), ice cover and altitude are the main factors affecting the climate of the Antarctic, which is the coldest place on Earth. Parts of Antarctica are facing the most rapid rates of anthropogenic climate change currently seen on the planet. Climate changes are occurring throughout Antarctica, affecting three major groups of environmental variables of considerable biological significance: temperature, water, UV-B radiation.Low diversity ecosystems are expected to be more vulnerable to global changes than high diversity ecosystems


2020 ◽  
Vol 6 (2) ◽  
pp. 64-68
Author(s):  
Nondira Khondhodjayeva ◽  
◽  
Nurmamat Rajabov ◽  

This article reveals the essence of the concept of "pheromones" and their biological significance. In the article variants of their application in agriculture for struggle against insects-pests are presented. The definition of term and classification of pheromones and their types are given: feromons of insects, feromons of fish, feromons of vertebrates, feromons of humans, fermons of plants, sexual feromons, anxiety feromons, trace feromons, epidemic feromons and their functions and significance for the representative's organism and the environment as a whole


10.2741/2124 ◽  
2007 ◽  
Vol 12 (1) ◽  
pp. 1041 ◽  
Author(s):  
María, C. Carreras

2020 ◽  
pp. 122-124
Author(s):  
Зиля Ахмерова

Аннотация. Деятельностный подход к организации учебных занятий при профессиональной подготовке специалистов представляет технологию индивидуализированного обучения. В данной статье проведен экскурс по проблеме деятельности. Деятельность рассматривается как способ участия индивида в преобразовании существующей действительности, как метод познания, как условие проявления и развития личности, как условие конструирования отношений между людьми. Функции деятельности непосредственно связаны не только с проектной деятельностью, но и с развитием личности. Поэтому деятельностная организация процесса проектирования как метода развития личности является актуальной. Кроме этого отмечается, что роль преподавателя в ходе осуществления личностно-деятельностного подхода заключается в умелой организации образовательно- профессиональной среды. Ключевые слова: деятельность, личность, учебная деятельность, проектная деятельность, личностно-деятельностные технологии. Аннотация. Адистерди кесиптик даярдоо учурунда окуу сабактарын уюштуруунун ишмердик ыкмасы жеке инсанга багытталган окутуу технологиясы болуп эсептелет. Бул макалада ишмердик маселеси боюнча экскурс жүргүзүлгөн. Ишмердүүлүк учурдагы чындыкты кайра өзгөртүп түзүүдөгү индивиддин катышуу жолу катары, таануу методу катары, инсандын өзүн көрсөтүүсүнүн жана өнүгүүсүнүн шарты катары, адамдар ортосунда мамиле түзүү ыкмасы катары каралат. Ишмердүүлүктүн функциялары долбоордук иштер менен гана эмес, инсандын өнүгүүсү менен да түздөн-түз байланыштуу. Ошондуктан инсанды өнүктүрүүнүн ыкмасы катары долбоорлоо процессинин ишмердик уюштурулушу актуалдуу. Мындан тышкары, жеке инсанга багытталган – ишмердик ыкмасын ишке ашыруудагы окутуучунун ролу билим берүүчүлүк-кесиптик чөйрөнү эптүү уюштуруу экендиги белгиленет. Түйүндүү сөздөр: ишмердүүлүк, инсан, окуу иши, долбоордук иш, жеке инсанга багытталган – ишмердик технологиялар. Annotation. The activity approach to organization of study in the profession- al training of specialists represents the individualized training technique. This article makes the insight into the activity issue. The activity is considered as a way of person’s participation in transformation of existing reality, as a way of learning, as a condition for personality demonstration and development, as a condition for building relations be- tween people. The functions of the activity are immediately associated with not only de- signing activity but with development of the personality. That is why activity organization of the designing process as a way of personality development is relevant. However, in the modern education, the personal and activity approach is to be com- bined with other approaches of the collective activity based on self-government and competitiveness. Key words: activity, personality, studies, designing activity, personal and activity techniques


2019 ◽  
Vol 26 (34) ◽  
pp. 6321-6338 ◽  
Author(s):  
Shuaimeng Guan ◽  
Kun Zhang ◽  
Jingan Li

Stem cell transplantation is an advanced medical technology, which brings hope for the treatment of some difficult diseases in the clinic. Attributed to its self-renewal and differential ability, stem cell research has been pushed to the forefront of regenerative medicine and has become a hot topic in tissue engineering. The surrounding extracellular matrix has physical functions and important biological significance in regulating the life activities of cells, which may play crucial roles for in situ inducing specific differentiation of stem cells. In this review, we discuss the stem cells and their engineering application, and highlight the control of the fate of stem cells, we offer our perspectives on the various challenges and opportunities facing the use of the components of extracellular matrix for stem cell attachment, growth, proliferation, migration and differentiation.


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