scholarly journals 16th FASEB Science Research Conference on Calcium and Cell Function: Calcium channels and signaling in health and disease

2016 ◽  
Vol 148 (5) ◽  
pp. 359-365
Author(s):  
Murali Prakriya ◽  
Stefan Feske
Keyword(s):  
Calcium Channels ◽  
Cell Function ◽  
Science Research ◽  
Research Conference ◽  
Health And Disease

scholarly journals Thyroid Hormone and the Neuroglia: Both Source and Target

2011 ◽  
Vol 2011 ◽  
pp. 1-16 ◽  
Author(s):  
Petra Mohácsik ◽  
Anikó Zeöld ◽  
Antonio C. Bianco ◽  
Balázs Gereben
Keyword(s):  
Thyroid Hormone ◽  
Cell Function ◽  
Hormone Regulation ◽  
Mediobasal Hypothalamus ◽  
Iodothyronine Deiodinase ◽  
Neuronal Gene ◽  
Health And Disease ◽  
And Function ◽  
The Brain

Thyroid hormone plays a crucial role in the development and function of the nervous system. In order to bind to its nuclear receptor and regulate gene transcription thyroxine needs to be activated in the brain. This activation occurs via conversion of thyroxine to T3, which is catalyzed by the type 2 iodothyronine deiodinase (D2) in glial cells, in astrocytes, and tanycytes in the mediobasal hypothalamus. We discuss how thyroid hormone affects glial cell function followed by an overview on the fine-tuned regulation of T3 generation by D2 in different glial subtypes. Recent evidence on the direct paracrine impact of glial D2 on neuronal gene expression underlines the importance of glial-neuronal interaction in thyroid hormone regulation as a major regulatory pathway in the brain in health and disease.

2020 FASEB Science Research Conference on Microbial Glycobiology, July 13‐14, 2020

2020 ◽  
Vol 34 (11) ◽  
pp. 14069-14072
Author(s):  
Nathalie Juge ◽  
Fikri Avci ◽  
Nichollas E. Scott ◽  
Carole Creuzenet ◽  
Miguel A. Valvano
Keyword(s):  
Science Research ◽  
Research Conference

scholarly journals Regulation of B-cell function by NF-kappaB c-Rel in health and disease

2020 ◽  
Vol 77 (17) ◽  
pp. 3325-3340
Author(s):  
Shrikanth C. Basavarajappa ◽  
Parameswaran Ramakrishnan
Keyword(s):  
B Cell ◽  
Cell Function ◽  
B Cell Function ◽  
Health And Disease ◽  
Nf Kappab
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