scholarly journals EXPERIMENTAL STREPTOBACILLUS MONILIFORMIS ARTHRITIS IN THE CHICK EMBRYO

1944 ◽  
Vol 80 (1) ◽  
pp. 59-64 ◽  
Author(s):  
G. John Buddingh

1. A strain of Streptobacillus moniliformis isolated from a case of rat bite fever in man has been found to produce infection of the developing chick embryo following inoculation of the chorio-allantois. 2. The disease in embryos is characterized by invasion of the blood stream and an almost exclusive localization of the infectious process to the synovial lining of the joints. 3. In the early stages of the development of the joint lesions the Streptobacillus moniliformis behaves as a facultative intracellular parasite within the cytoplasm of the synovial lining cells. Conditions favorable for the growth of the microorganisms are maintained only temporarily. The infection appears to be self-limiting in nature.

1989 ◽  
Vol 9 (2) ◽  
pp. 49-51 ◽  
Author(s):  
P. A. Revell

BMJ ◽  
1966 ◽  
Vol 1 (5497) ◽  
pp. 1213-1214 ◽  
Author(s):  
R. C. McGill ◽  
A. M. Martin ◽  
P. N. Edmunds

1995 ◽  
Vol 170 (2) ◽  
pp. 299-313 ◽  
Author(s):  
A.Ruiz i Altaba ◽  
M. Placzek ◽  
M. Baldassare ◽  
J. Dodd ◽  
T.M. Jessell

1973 ◽  
Vol 148 (3) ◽  
pp. 265-274 ◽  
Author(s):  
R.G. Butcher ◽  
Lucille Bitensky ◽  
B. Cashman ◽  
J. Chayen

1988 ◽  
Vol 222 (4) ◽  
pp. 401-407 ◽  
Author(s):  
Ruth Calvente ◽  
Ramón Carmona ◽  
Francisco Abadí-Molina ◽  
Francisco Abadía-Fenoll

Development ◽  
1960 ◽  
Vol 8 (4) ◽  
pp. 369-375
Author(s):  
P. H. S. Silver

It seems to be generally accepted that experimenting in ovo on the chick during the early stages of development (up to about 48 hours) is fraught with the greatest difficulty. After about this time no serious technical problems arise and a high proportion of successful results can be expected. It is natural to ask why there should be this change-over from extreme difficulty to reasonable simplicity. New (1955) attributed to this ‘inaccessibility of the chick embryo in the egg’ the invention of his own and many other in vitro methods during the last 30 years. There is no doubt that, when short-term experiments only are required, in vitro methods will probably always be preferred. But all in vitro methods suffer from the disadvantage that the embryo cannot be expected to survive for more than 48 hours or so after explantation.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Bethany A. Croker ◽  
Alexander Prudence ◽  
Paul A. Wilson ◽  
Rod Givney ◽  
Gabrielle O'Kane

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