scholarly journals NUTRITIONAL CYTOPENIA IN MONKEYS RECEIVING THE GOLDBERGER DIET

1940 ◽  
Vol 72 (4) ◽  
pp. 463-477 ◽  
Author(s):  
Paul L. Day ◽  
William C. Langston ◽  
William J. Darby ◽  
Joel G. Wahlin ◽  
Virginia Mims
Keyword(s):  
Ascorbic Acid ◽  
Nicotinic Acid ◽  
Rhesus Monkeys ◽  
Liver Extract ◽  
Normal Growth ◽  
Normal Blood ◽  
Blood Picture ◽  
Deficient Diet ◽  
The Face ◽  
The Relationship

Experiments are reported upon young rhesus monkeys which were given a diet essentially the same as the Goldberger black tongue-producing diet, supplemented in various ways. Those receiving the unsupplemented diet developed the syndrome characterized by leucopenia, anemia, gingivitis, diarrhea, and death, which has been previously described in monkeys receiving our diet of refined foodstuffs. An animal receiving the Goldberger diet supplemented with ascorbic acid and liver extract exhibited normal growth and development and has maintained a normal blood picture for approximately 2 years. Likewise, the feeding of a crude liver extract to an animal with profound anemia and leucopenia was followed by a dramatic reticulocyte response and ultimate recovery. However, the ash of liver extract failed to maintain a normal blood picture or to prolong life. Supplementing the diet with ascorbic acid, thiamin chloride, nicotinic acid (or amide), and riboflavin failed to prevent the leucopenia, gingivitis, diarrhea, and death. The combination of nicotinic acid and riboflavin, however, appeared to have a definite erythropoietic effect. Shigella paradysenteriae was isolated from the stools of several of the animals which received the deficient diet. Further studies are needed to clarify the relationship between the deficiency, the infection, and the blood picture. Three of the animals exhibited edema of the face. It is evident that the Goldberger diet, even when supplemented with nicotinic acid, riboflavin, thiamin, and ascorbic acid, is inadequate for maintenance of health in the young monkey. The nature of the deficiency manifestations would indicate that the diet is deficient in the substance or substances which we have previously termed vitamin M.

scholarly journals THE EFFECT OF DIET ON THE HEMOGLOBIN, ERYTHROCYTE, AND LEUKOCYTE CONTENT OF THE BLOOD OF THE RHESUS MONKEY (MACACA MULATTA)

Blood ◽  
1947 ◽  
Vol 2 (2) ◽  
pp. 154-163 ◽  
Author(s):  
EDITH SEYMOUR JONES ◽  
KEITH B. MCCALL ◽  
C. A. ELVEHJEM ◽  
P. F CLARK
Keyword(s):  
Ascorbic Acid ◽  
Macaca Mulatta ◽  
Rhesus Monkeys ◽  
Leukocyte Count ◽  
Liver Extract ◽  
Total Leukocyte Count ◽  
Blood Picture ◽  
Neutrophil Lymphocyte Ratio ◽  
B Vitamin ◽  
Nutritional Studies

Abstract 1. Rhesus monkeys fed purified rations supplemented with adequate amounts of the B vitamins, ascorbic acid, and whole liver substance maintained the following average blood picture: See PDF for Table 2. Natural diets or purified rations supplemented with liver extract do not support the above blood picture. The hemoglobin is lower and there is an increase in the range of the total leukocyte count and in the neutrophil-lymphocyte ratio to 2.0 ([unknown]). These figures are similar to the values in the literature and generally accepted as the normal. 3. Previous reports have shown the characteristic blood dyscrasias which develop when monkeys are fed certain B vitamin-deficient diets. These changes are summarized graphically in this paper. 4. The importance of determining the concentration of hemoglobin and the formed elements of the blood as a diagnostic test in nutritional studies has been shown.

scholarly journals NUTRITIONAL CYTOPENIA (VITAMIN M DEFICIENCY) IN THE MONKEY

1938 ◽  
Vol 68 (6) ◽  
pp. 923-940 ◽  
Author(s):  
William C. Langston ◽  
William J. Darby ◽  
Carroll F. Shukers ◽  
Paul L. Day
Keyword(s):  
Nicotinic Acid ◽  
Liver Extract ◽  
Vitamin B ◽  
Good Growth ◽  
Deficient Diet ◽  
Polished Rice ◽  
Whole Wheat ◽  
Body Development ◽  
Loss Of Weight ◽  
Brewers Yeast

Young rhesus monkeys (Macaca mulatta) were given a diet containing casein, polished rice, whole wheat, salt mixture, sodium chloride, cod liver oil, and ascorbic acid. They developed a syndrome characterized by anemia, leukopenia, and loss of weight. Ulceration of the gums and diarrhea were common, and death occurred between the 26th and 100th day. 4 monkeys were given the deficient diet supplemented with 1 mg. of riboflavin daily, and these developed the characteristic signs and died. in periods of time similar to the survival of monkeys receiving the deficient diet alone. Nicotinic acid, either alone or in combination with riboflavin and thiamin chloride, failed to alter appreciably the course of the deficiency manifestations. Thus, it is evident that this nutritional cytopenia is not the result of a deficiency of vitamin B, riboflavin, or nicotinic acid. The deficient diet supplemented with either 10 gm. of dried brewers' yeast or 2 gm. of liver extract (Cohn fraction G) daily supported good growth, permitted normal body development, and maintained a normal blood picture over long periods. It is obvious that yeast and liver extract contain a substance essential to the nutrition of the monkey which is not identical with any of those factors of the vitamin B complex that have been chemically identified. We have proposed the term vitamin M for this factor which prevents nutritional cytopenia in the monkey.

The Relationship between Seeker and Spiritual Guide as portrayed in contemporary Western Sufi Autobiographies

2011 ◽  
Vol 5 (2) ◽  
pp. 297-332
Author(s):  
Kate Zebiri
Keyword(s):  
Life Writing ◽  
New Age ◽  
The Self ◽  
Individual Autonomy ◽  
Religious Authority ◽  
The Face ◽  
The Relationship ◽  
Insight Into ◽  
Continuity And Discontinuity

This article aims to explore the Shaykh-mur?d (disciple) or teacher-pupil relationship as portrayed in Western Sufi life writing in recent decades, observing elements of continuity and discontinuity with classical Sufism. Additionally, it traces the influence on the texts of certain developments in religiosity in contemporary Western societies, especially New Age understandings of religious authority. Studying these works will provide an insight into the diversity of expressions of contemporary Sufism, while shedding light on a phenomenon which seems to fly in the face of contemporary social and religious trends which deemphasize external authority and promote the authority of the self or individual autonomy.

Mimetic Monsters

2010 ◽  
Vol 4 (1) ◽  
pp. 85-93
Author(s):  
Timothy Beal
Keyword(s):  
The Other ◽  
Jewish Tradition ◽  
Book Of Job ◽  
Edge Of Chaos ◽  
The Face ◽  
The Relationship

This article reads between two recent explorations of the relationship between religion, chaos, and the monstrous: Catherine Keller’s Face of the Deep and Author's Religion and Its Monsters. Both are oriented toward the edge of chaos and order; both see the primordial and chaotic as generative; both pursue monstrous mythological figures as divine personifications of primordial chaos; both find a deep theological ambivalences in Christian and Jewish tradition with regard to the monstrous, chaotic divine; both are critical of theological and cultural tendencies to demonize chaos and the monstrous; and finally, both read the divine speech from the whirlwind in the book of Job as a revelation of divine chaos. But whereas one sees it as a call for laughter, a chaotic life-affirming laughter with Leviathan in the face of the deep, the other sees it as an incarnation of theological horror, leaving Job and the reader overwhelmed and out-monstered by God. Must it be one way or the other? Can laughter and horror coincide in the face of the deep?

INTERCONNECTION OF SUSTAINABLE DEVELOPMENT COMPONENTS FOR THE INDIGENOUS PEOPLES OF THE NORTH

2020 ◽  
Vol 2 (8) ◽  
pp. 101-110
Author(s):  
N. N. ILYSHEVA ◽  
◽  
E. V. KARANINA ◽  
G. P. LEDKOV ◽  
E. V. BALDESKU ◽  
...  
Keyword(s):  
Climate Change ◽  
Sustainable Development ◽  
Economic Development ◽  
Indigenous Peoples ◽  
Ecological Footprint ◽  
Positive Relationship ◽  
The North ◽  
Strong Positive Relationship ◽  
The Face ◽  
The Relationship

The article deals with the problem of achieving sustainable development. The purpose of this study is to reveal the relationship between the components of sustainable development, taking into account the involvement of indigenous peoples in nature conservation. Climate change makes achieving sustainable development more difficult. Indigenous peoples are the first to feel the effects of climate change and play an important role in the environmental monitoring of their places of residence. The natural environment is the basis of life for indigenous peoples, and biological resources are the main source of food security. In the future, the importance of bioresources will increase, which is why economic development cannot be considered independently. It is assumed that the components of resilience are interrelated and influence each other. To identify this relationship, a model for the correlation of sustainable development components was developed. The model is based on the methods of correlation analysis and allows to determine the tightness of the relationship between economic development and its ecological footprint in the face of climate change. The correlation model was tested on the statistical materials of state reports on the environmental situation in the Khanty-Mansiysk Autonomous Okrug – Yugra. The approbation revealed a strong positive relationship between two components of sustainable development of the region: economy and ecology.

Plebiscitary Politics and the Threats to Legality

2019 ◽  
pp. 275-289
Author(s):  
Claudius Härpfer
Keyword(s):  
The State ◽  
Short Term ◽  
Political Processes ◽  
The Face ◽  
State Of Affairs ◽  
The Relationship

In recent times we find many plebiscitary acts that seek to democratically legitimize political processes in any direction. They have in common that they interrupt the normal routine of representative democracies to a certain degree and create an extra-daily state of affairs, which entails not only direct but also indirect consequences. The text attempts to systematize some of these mechanisms from a Weberian perspective using Brexit as an example. After a brief overview of Weber’s short-term politically inspired statements on plebiscitary democracy, the text systematizes Weber’s understanding of the state as a bureaucratic apparatus that requires any kind of leader to be controlled. Subsequently, the text discusses the relationship between domination, legality, and rationality in order to finally point out the danger of erosion of truth and legality through the emergence of competing consensus communities in the face of competing conceptions of order.

Alberto Blest Gana: Four Chronicles and a Novel

2021 ◽  
Vol 5 (1) ◽  
pp. 123-135
Author(s):  
Laura Janina Hosiasson
Keyword(s):  
Utopian Fiction ◽  
Alberto Blest Gana ◽  
Close Relationship ◽  
The Face ◽  
The Government ◽  
The Relationship ◽  
Shed Light

Abstract Four chronicles written by Alberto Blest Gana between April and May 1862 in the newspaper La voz de Chile, months before the publication of his novel Mariluán, shed light on the close relationship between his production as chronicler and writer. Among the various faits divers discussed in the columns, the issue of a Mapuche delegation’s arrival in Santiago to hold a parlamento with the government about border disputes arises. The oscillating attitude of the chronicler in the face of otherness and his prejudiced comments, which are at the same time full of doubts and perplexities, serve as an incentive for his composing a utopian fiction. This article aims to examine the connections in the relationship between Blest Gana chronicler and novelist to expand the reading possibilities of Mariluán.

Surgical Anatomy for Extended Facelift Techniques

2020 ◽  
Vol 36 (03) ◽  
pp. 309-316
Author(s):  
Ozcan Cakmak ◽  
Ismet Emrah Emre
Keyword(s):  
Facial Nerve ◽  
Soft Tissues ◽  
Extended Techniques ◽  
Surgical Anatomy ◽  
Superficial Musculoaponeurotic System ◽  
Increased Risk ◽  
The Face ◽  
Facial Soft Tissues ◽  
Relationship Of ◽  
The Relationship

AbstractPreservation of the facial nerve is crucial in any type of facial procedure. This is even more important when performing plastic surgery on the face. An intricate knowledge of the course of the facial nerve is a requisite prior to performing facelifts, regardless of the technique used. The complex relationship of the ligaments and the facial nerve may put the nerve at an increased risk of damage, especially if its anatomy is not fully understood. There are several danger zones during dissection where the nerve is more likely to be injured. These include the areas where the nerve branches become more superficial in the dissection plane, and where they traverse between the retaining ligaments of the face. Addressing these ligaments is crucial, as they prevent the transmission of traction during facelifts. Without sufficient release, a satisfying pull on the soft tissues may be limited. Traditional superficial musculoaponeurotic system techniques such as plication or imbrication do not include surgical release of these attachments. Extended facelift techniques include additional dissection to release the retaining ligaments to obtain a more balanced and healthier look. However, these techniques are often the subject of much debate due to the extended dissection that carries a higher risk of nerve complications. In this article we aim to present the relationship of both the nerve and ligaments with an emphasis on the exact location of these structures, both in regard to one another and to their locations within the facial soft tissues, to perform extended techniques safely.

Research on Choice of Logistics Mode of B2C Enterprises with FAHP

2014 ◽  
Vol 672-674 ◽  
pp. 2211-2216
Author(s):  
Yang Lv ◽  
Hong Sheng Sun ◽  
Xi Fu Wang
Keyword(s):  
Economic Integration ◽  
Analytical Hierarchy Process ◽  
Economic Globalization ◽  
Fuzzy Analytical Hierarchy Process ◽  
Logistics Services ◽  
Logistics Mode ◽  
The Face ◽  
Hierarchy Process ◽  
The Relationship

Under the background of economic globalization and regional economic integration, B2C enterprises begin to focus on how to handle the relationship between logistics services and E-commerce services in the face of intense competition from other companies. This paper proposes a fuzzy analytical hierarchy process (FAHP) approach to select the logistics mode of B2C electronic commerce companies. In addition, a case study is presented to demonstrate how the approach can help in solving such problems in practice.

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