scholarly journals THE DISTRIBUTION IN THE BLOOD AND LYMPH OF PNEUMOCOCCUS TYPE III INJECTED INTRAVENOUSLY IN RABBITS, AND THE EFFECT OF TREATMENT WITH SPECIFIC ANTISERUM ON THE INFECTION OF THE LYMPH

1937 ◽  
Vol 65 (4) ◽  
pp. 469-485 ◽  
Author(s):  
Madeleine E. Field ◽  
Morris F. Shaffer ◽  
John F. Enders ◽  
Cecil K. Drinker
Keyword(s):  
Specific Antibody ◽  
Thoracic Duct ◽  
Pneumococcal Infection ◽  
Thoracic Duct Lymph ◽  
Lymphatic Endothelium ◽  
Type Iii ◽  
Virulent Type ◽  
Duct Lymph ◽  
Effect Of Treatment ◽  
Pneumococcus Type

Experiments are described which show that in rabbits infected intravenously with virulent Type III pneumococci, these organisms are found not only in the thoracic duct lymph, as previously reported, but also in lymph from the cervical and leg lymphatics. The nonmotile bacteria must have crossed both vascular and lymphatic endothelium in reaching the lymph. Intracellular transportation by phagocytes is apparently not the means by which this is effected. The intravenous and intraperitoneal injection of large amounts of homologous type-specific antibody fails even after many hours to terminate or permanently reduce the pneumococcal infection of the lymph. The failure of antiserum to sterilize the lymph is discussed.

scholarly journals THE EMIGRATION OF PNEUMOCOCCI TYPE III FROM THE BLOOD INTO THE THORACIC DUCT LYMPH OF RABBITS, AND THE SURVIVAL OF THESE ORGANISMS IN THE LYMPH FOLLOWING INTRAVENOUS INJECTION OF SPECIFIC ANTISERUM

1935 ◽  
Vol 62 (6) ◽  
pp. 849-860 ◽  
Author(s):  
Cecil K. Drinker ◽  
John F. Enders ◽  
Morris F. Shaffer ◽  
Octa C. Leigh
Keyword(s):  
Intravenous Injection ◽  
Thoracic Duct ◽  
Intact Animal ◽  
Horse Serum ◽  
High Titre ◽  
Thoracic Duct Lymph ◽  
Type Iii ◽  
Virulent Type ◽  
Duct Lymph ◽  
Living Organisms

1. Rabbits injected intravenously with a large dose of a virulent Type III Pneumococcus develop a bacteremia, and within an hour organisms may be cultivated from the thoracic duct lymph. The rapidity with which entrance into the lymph occurs appears to be correlated with the size of the dose injected. 2. The organisms may become more numerous in the lymph than in the blood. 3. If homologous or heterologous antisera are injected, the blood may be sterilized, but though the organisms may be lessened in the lymph, sterilization at least within 4 hours is not secured, and in the intact animal living organisms must continue to enter the blood with the thoracic duct lymph. 4. In infected rabbits after intravenous injection of considerable quantities of antisera containing moderate amounts of agglutinin, no antibody appears in the thoracic duct lymph although the presence of horse serum may be detected. The injection of a very large quantity of antiserum containing a high titre of agglutinin is followed by the penetration of antibody into the lymph. This, however, has failed to sterilize the lymph or to permanently affect the rate of multiplication of the pneumococci.

Measurement of Pancreatic Enzymes in Human Thoracic Duct Lymph

1960 ◽  
Vol 38 (6) ◽  
pp. 954-956 ◽  
Author(s):  
Allan E. Dumont ◽  
John H. Mulholland
Keyword(s):  
Thoracic Duct ◽  
Pancreatic Enzymes ◽  
Thoracic Duct Lymph ◽  
Duct Lymph

Thoracic duct lymph. Relative contribution from splanchnic and muscle tissue

Diabetes ◽  
1993 ◽  
Vol 42 (5) ◽  
pp. 720-731 ◽  
Author(s):  
G. M. Steil ◽  
M. A. Meador ◽  
R. N. Bergman
Keyword(s):  
Muscle Tissue ◽  
Thoracic Duct ◽  
Thoracic Duct Lymph ◽  
Relative Contribution ◽  
Duct Lymph

Dynamics of glucose production and uptake are more closely related to insulin in hindlimb lymph than in thoracic duct lymph

Diabetes ◽  
1994 ◽  
Vol 43 (2) ◽  
pp. 180-190 ◽  
Author(s):  
R. A. Poulin ◽  
G. M. Steil ◽  
D. M. Moore ◽  
M. Ader ◽  
R. N. Bergman
Keyword(s):  
Thoracic Duct ◽  
Glucose Production ◽  
Thoracic Duct Lymph ◽  
Duct Lymph

Lymphatic pump treatment mobilizes leukocytes from the gut associated lymphoid tissue into thoracic duct lymph

2008 ◽  
Vol 11 (4) ◽  
pp. 149 ◽  
Author(s):  
Artur Schander ◽  
Melissa K. Bearden ◽  
Jamie B. Huff ◽  
Arthur Williams ◽  
Scott T. Stoll ◽  
...  
Keyword(s):  
Thoracic Duct ◽  
Lymphoid Tissue ◽  
Thoracic Duct Lymph ◽  
Lymphatic Pump Treatment ◽  
Duct Lymph
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