scholarly journals Concerning the localization of steroids in centrioles and basal bodies by immunofluorescence.

1978 ◽  
Vol 76 (2) ◽  
pp. 255-260 ◽  
Author(s):  
I Nenci ◽  
E Marchetti
Keyword(s):  
Cell Growth ◽  
Basal Bodies ◽  
Immunofluorescence Technique ◽  
Cell Growth And Differentiation ◽  
Affect Cell Growth

Specific steroid antibodies, by the immunofluorescence technique, regularly reveal fluorescent centrioles and cilia-bearing basal bodies in target and nontarget cells. Although the precise identity of the immunoreactive steroid substance has not yet been established, it seems noteworthy that exogenous steroids can be vitally concentrated by centrioles, perhaps by exchange with steroids already present at this level. This unexpected localization suggests that steroids may affect cell growth and differentiation in some way different from the two-step receptor mechanism.

scholarly journals IL-4 and anti-CD40 protect against Fasmediated B cell apoptosis and induce B cell growth and differentiation

1996 ◽  
Vol 8 (5) ◽  
pp. 791-798 ◽  
Author(s):  
Kenji Nakanishi ◽  
Kiyoshi Matsui ◽  
Shin-ichiro Kashiwamura ◽  
Yasuhiro Nishioka ◽  
Jun Nomura ◽  
...  
Keyword(s):  
Cell Growth ◽  
B Cell ◽  
Cell Apoptosis ◽  
Cell Growth And Differentiation

Immunologic Control of Vascular Cell Growth and Differentiation

1989 ◽  
Vol 14 ◽  
pp. S82-S84
Author(s):  
Göran K. Hansson ◽  
Jan Holm ◽  
Lena Jonasson ◽  
Paul S. Seifert ◽  
Sten Stemme
Keyword(s):  
Cell Growth ◽  
Vascular Cell ◽  
Cell Growth And Differentiation ◽  
Immunologic Control

scholarly journals p300 Alters Keratinocyte Cell Growth and Differentiation through Regulation of p21Waf1/CIP1

PLoS ONE ◽  
2010 ◽  
Vol 5 (1) ◽  
pp. e8369 ◽  
Author(s):  
Ping-Pui Wong ◽  
Adam Pickard ◽  
Dennis J. McCance
Keyword(s):  
Cell Growth ◽  
Keratinocyte Cell ◽  
Cell Growth And Differentiation

scholarly journals Prohibitins Regulate Membrane Protein Degradation by the m-AAA Protease in Mitochondria

1999 ◽  
Vol 19 (5) ◽  
pp. 3435-3442 ◽  
Author(s):  
Gregor Steglich ◽  
Walter Neupert ◽  
Thomas Langer
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Cell Growth ◽  
Membrane Proteins ◽  
Eukaryotic Cells ◽  
Mitochondrial Morphology ◽  
Regulatory Effect ◽  
Inner Membrane ◽  
Functional Activities ◽  
Native Molecular Mass ◽  
Affect Cell Growth

ABSTRACT Prohibitins comprise a protein family in eukaryotic cells with potential roles in senescence and tumor suppression. Phb1p and Phb2p, members of the prohibitin family in Saccharomyces cerevisiae, have been implicated in the regulation of the replicative life span of the cells and in the maintenance of mitochondrial morphology. The functional activities of these proteins, however, have not been elucidated. We demonstrate here that prohibitins regulate the turnover of membrane proteins by the m-AAA protease, a conserved ATP-dependent protease in the inner membrane of mitochondria. The m-AAA protease is composed of the homologous subunits Yta10p (Afg3p) and Yta12p (Rca1p). Deletion ofPHB1 or PHB2 impairs growth of Δyta10 or Δyta12 cells but does not affect cell growth in the presence of the m-AAA protease. A prohibitin complex with a native molecular mass of approximately 2 MDa containing Phb1p and Phb2p forms a supercomplex with them-AAA protease. Proteolysis of nonassembled inner membrane proteins by the m-AAA protease is accelerated in mitochondria lacking Phb1p or Phb2p, indicating a negative regulatory effect of prohibitins on m-AAA protease activity. These results functionally link members of two conserved protein families in eukaryotes to the degradation of membrane proteins in mitochondria.

Clonal Selection in B-Cell Growth and Differentiation

1987 ◽  
Vol 99 (1) ◽  
pp. 53-69 ◽  
Author(s):  
Tomas Leanderson ◽  
Jan Andersson ◽  
Ramanujam Rajasekar
Keyword(s):  
Cell Growth ◽  
B Cell ◽  
Clonal Selection ◽  
Cell Growth And Differentiation
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