scholarly journals AN ELECTRON MICROSCOPE STUDY OF MOUSE MAST CELLS ARISING IN VIVO AND IN VITRO

1971 ◽  
Vol 48 (3) ◽  
pp. 676-683 ◽  
Author(s):  
John W. Combs
1952 ◽  
Vol 96 (2) ◽  
pp. 107-114 ◽  
Author(s):  
Thomas G. Morrione

Collagen fibers have been formed in vitro by the action of heparm on solutions of collagen. Heparin was found to be effective in inducing collagen fiber formation when present in concentrations as low as 1–80,000. It is postulated that mast cells, by virtue of the heparin which they produce, may play a role in the formation of collagen.


1967 ◽  
Vol 2 (3) ◽  
pp. 371-376
Author(s):  
J. A. CHAPMAN ◽  
J. GOUGH ◽  
M. W. ELVES

Macrophages which develop in cultures of human peripheral blood have the typical ultrastructural features of macrophages occurring in other situations, in vivo and in vitro. The cultured cells usually have irregular nuclei and the cytoplasm possesses numerous digestion vacuoles containing debris; the cell outline is irregular with many filopodia. Other cells were laden with membrane-bounded granular bodies containing periodic-structured material of regular outline. Although it is concluded that no evidence about cell ancestry can be adduced from this morphological study, it seems likely from other work that many of these macrophages arise from lymphocytes.


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