scholarly journals THE EFFECT OF PHYTOHEMAGGLUTININ ON RIBONUCLEIC ACID SYNTHESIS AND HISTONE ACETYLATION IN EQUINE LEUKOCYTES

1967 ◽  
Vol 35 (2) ◽  
pp. 477-482 ◽  
Author(s):  
B. G. T. Pogo ◽  
V. G. Allfrey ◽  
A. E. Mirsky
Keyword(s):  
Histone Acetylation ◽  
Ribonucleic Acid ◽  
Acid Synthesis

scholarly journals Regulation of ribonucleic acid synthesis by polyamines. Reversal by spermine of inhibition by methylglyoxal bis(guanylhydrazone) of ribonucleic acid synthesis and histone acetylation in rabbit heart

1975 ◽  
Vol 152 (1) ◽  
pp. 91-98 ◽  
Author(s):  
C M Caldarera ◽  
A Casti ◽  
C Guarnier ◽  
G Moruzzi
Keyword(s):  
Histone Acetylation ◽  
Ribonucleic Acid ◽  
Specific Radioactivity ◽  
Acid Synthesis ◽  
Rabbit Heart ◽  
Decarboxylase Activity ◽  
Perfused Heart ◽  
Rna Transcription ◽  
Adenosylmethionine Decarboxylase ◽  
The Relationship

The relationship between polyamines and RNA synthesis was studied by considering the action of spermine on histone acetylation in perfused heart. In addition, the effect of methylglyoxal bis(guanylhydrazone), inhibitor of putrescine-activated S-adenosylmethionine decarboxylase activity, on RNA and polyamine specific radioactivity and on acetylation of histone fractions was also investigated in perfused heart. Different concentrations of spermine and/or methylglyoxas bis(guanylhydrazone) were injected into the heart, 15 min after beginning the perfusion. The results demonstrate that spermine stimulates the specific radioactivity of RNA of subcellular fractions. Acetylation of the arginine-rich histone fractions, involved in the regulation of RNA transcription, is enhanced by spermine. The perfusion with methylglyoxal bis(guanylhydrazone) causes a decrease in the specific radioactivity of polyamines and RNA, and in acetylation of histone fractions. However, spermine is able to reverse the methylglyoxal bis(guanylhydrazone) inhibition when injected simultaneously. From these results we may assume a possible role for spermine in the regulation of RNA transcription.

scholarly journals Patterns of Ribonucleic Acid Synthesis in T5-infected Escherichia coli

1970 ◽  
Vol 245 (10) ◽  
pp. 2679-2692
Author(s):  
David A. Sirbasku ◽  
John M. Buchanan
Keyword(s):  
Escherichia Coli ◽  
Ribonucleic Acid ◽  
Acid Synthesis

scholarly journals The Control of Ribonucleic Acid Synthesis in Escherichia coli

1970 ◽  
Vol 245 (9) ◽  
pp. 2309-2318 ◽  
Author(s):  
Michael Cashel ◽  
Barbara Kalbacher
Keyword(s):  
Escherichia Coli ◽  
Ribonucleic Acid ◽  
Acid Synthesis

scholarly journals Regulation of Host Ribonucleic Acid Synthesis in Bacteriophage T3-infected Cells

1974 ◽  
Vol 249 (6) ◽  
pp. 1787-1791
Author(s):  
S.P. Mahadik ◽  
B. Dharmgrongartama ◽  
P.R. Srinivasan
Keyword(s):  
Ribonucleic Acid ◽  
Acid Synthesis ◽  
Infected Cells

scholarly journals Patterns of Ribonucleic Acid Synthesis in T5-infected Escherichia coli

1971 ◽  
Vol 246 (6) ◽  
pp. 1665-1676
Author(s):  
David A. Sirbasku ◽  
John M. Buchanan
Keyword(s):  
Escherichia Coli ◽  
Ribonucleic Acid ◽  
Acid Synthesis
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